L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-07

AUTHORS

A. Slominski, R. Costantino

ABSTRACT

Exposure of hamster amelanotic melanoma cells to L-tyrosine caused a time-dependent increase of tyrosinase protein concentrations, tyrosinase activity and level of cell pigmentation. In contrast, Northern blot analysis using mouse tyrosinase cDNA showed a steady level of tyrosinase mRNA. Thus in hamster melanoma cells the stimulation of intracellular tyrosinase concentration by L-tyrosine is mediated mainly via a posttranscriptional mechanism. More... »

PAGES

721-724

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01958826

DOI

http://dx.doi.org/10.1007/bf01958826

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006909025

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1906010


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