Hypertrophy of pulmonary arteries and arterioles with cor pulmonale in rats induced by seneciphylline, a pyrrolizidine alkaloid View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1977-04

AUTHORS

K. Ohtsubo, Y. Ito, M. Saito, T. Furuya, M. Hikichi

ABSTRACT

Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, induced, as do also monoclotaline, etc., a marked arterial and arteriolar hypertrophy of the lung of young Wistar rats a month after a single s. c. injection of 50–80 mg/kg. Cor pulmonale with leftward shift of the ventricular septum was also noted.

PAGES

498-499

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01922233

DOI

http://dx.doi.org/10.1007/bf01922233

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009391748

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/862745


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