Effect of various stressors on the levels of lipid peroxide, antioxidants and Na+, K+-ATPase actrivity in rat brain View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-04

AUTHORS

A. A. Shaheen, A. A. Abd El-Fattah, M. Z. Gad

ABSTRACT

The level of malondialdehyde (MDA), an index of lipid peroxidation, and the antioxidants superoxide dismutase (SOD) and glutathione (GSH), as well as the activity of Na+, K(+)-ATPase, were assessed in whole rat brain after immobilization, anemic hypoxia (NaNO2) and 72 h starvation. The effect of these stressors on plasma glucose and corticosterone levels was also observed. Hypoxia and starvation stimulated the lipid peroxide formation in brain as indicated by an increase in the level of MDA, being higher after starvation than hypoxia. Brain SOD activity was also increased in response to hypoxia and starvation while GSH content was only diminished in hypoxia. However, neither MDA nor antioxidants were affected by immobilization. On the other hand, the activity of brain Na+, K(+)-ATPase was significantly increased by immobilization and hypoxia but decreased in starvation. A similar pattern of change was also observed in plasma glucose and corticosterone levels in response to these stressors. These results elucidate differences in the biochemical response of animals towards various types of stress, with increased lipid peroxide formation in hypoxia and starvation. More... »

PAGES

336-339

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01919536

DOI

http://dx.doi.org/10.1007/bf01919536

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038881441

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8620936


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antioxidants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Glucose", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Corticosterone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glutathione", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypoxia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lipid Peroxidation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Malondialdehyde", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Wistar", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Restraint, Physical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sodium-Potassium-Exchanging ATPase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Starvation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stress, Physiological", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Superoxide Dismutase", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Cairo University", 
          "id": "https://www.grid.ac/institutes/grid.7776.1", 
          "name": [
            "Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt)"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shaheen", 
        "givenName": "A. A.", 
        "id": "sg:person.0603467660.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603467660.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cairo University", 
          "id": "https://www.grid.ac/institutes/grid.7776.1", 
          "name": [
            "Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt)"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abd El-Fattah", 
        "givenName": "A. A.", 
        "id": "sg:person.01254572024.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254572024.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cairo University", 
          "id": "https://www.grid.ac/institutes/grid.7776.1", 
          "name": [
            "Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt)"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gad", 
        "givenName": "M. Z.", 
        "id": "sg:person.0615762501.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615762501.20"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1006/abbi.1993.1189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001771289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3940(89)90217-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003555610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3940(89)90217-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003555610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-2697(78)90342-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003753168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0009-3084(90)90145-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004736199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0009-3084(90)90145-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004736199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jcp.15.4.374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017856973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jcp.22.2.246-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020960118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(89)90210-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021177561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2736(89)90210-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021177561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1988.tb02462.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027883512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00999694", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029323126", 
          "https://doi.org/10.1007/bf00999694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00999391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030099229", 
          "https://doi.org/10.1007/bf00999391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0031-9384(90)90295-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030295229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0031-9384(90)90295-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030295229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1978.tb00107.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032811744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-291x(77)80151-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036311868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0300-595x(76)80040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037673112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0300-595x(76)80040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037673112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0031-9384(86)90285-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039567881"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0031-9384(86)90285-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039567881"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3940(93)90085-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040449013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3940(93)90085-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040449013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(85)90606-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040823958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(85)90606-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040823958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(77)90152-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046002639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(77)90152-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046002639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y77-025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050012851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1976.tb01562.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050742707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0940-2993(11)80224-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052211579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-1003614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057478193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-1003626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057478205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.36.2.169", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070735201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-88-5-671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073735561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076155626", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076750128", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078281641", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079021792", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079033956", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079247873", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1988.64.4.1333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079713227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079733111", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080219994", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082619943", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082866369", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1996-04", 
    "datePublishedReg": "1996-04-01", 
    "description": "The level of malondialdehyde (MDA), an index of lipid peroxidation, and the antioxidants superoxide dismutase (SOD) and glutathione (GSH), as well as the activity of Na+, K(+)-ATPase, were assessed in whole rat brain after immobilization, anemic hypoxia (NaNO2) and 72 h starvation. The effect of these stressors on plasma glucose and corticosterone levels was also observed. Hypoxia and starvation stimulated the lipid peroxide formation in brain as indicated by an increase in the level of MDA, being higher after starvation than hypoxia. Brain SOD activity was also increased in response to hypoxia and starvation while GSH content was only diminished in hypoxia. However, neither MDA nor antioxidants were affected by immobilization. On the other hand, the activity of brain Na+, K(+)-ATPase was significantly increased by immobilization and hypoxia but decreased in starvation. A similar pattern of change was also observed in plasma glucose and corticosterone levels in response to these stressors. These results elucidate differences in the biochemical response of animals towards various types of stress, with increased lipid peroxide formation in hypoxia and starvation.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf01919536", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1295005", 
        "issn": [
          "1420-682X", 
          "1420-9071"
        ], 
        "name": "Cellular and Molecular Life Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "52"
      }
    ], 
    "name": "Effect of various stressors on the levels of lipid peroxide, antioxidants and Na+, K+-ATPase actrivity in rat brain", 
    "pagination": "336-339", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b9360d2a895bf2780830d44f52629ca1d23acfcedbf277953194fdbfc8924e60"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8620936"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0376547"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01919536"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1038881441"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01919536", 
      "https://app.dimensions.ai/details/publication/pub.1038881441"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:13", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000500.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF01919536"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01919536'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01919536'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01919536'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01919536'


 

This table displays all metadata directly associated to this object as RDF triples.

251 TRIPLES      21 PREDICATES      82 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01919536 schema:about N0092b19de93444578dfcb4673429d590
2 N0415a45f5b74428b87cc4eca336a00d3
3 N0a702de141e14e2393c5718d63f36b6f
4 N0b53582cace3442385d997ba8bd98087
5 N120c924384d247778784d545040a8493
6 N289a686fde774e179855e8d77b7d86b9
7 N39caf5e0317748f5aafb5ffe99098fc0
8 N5839f2fa293b4c118bb3ea267d216627
9 N624b2efc471642e99bc5d0e2fd017e60
10 N8cb0f8f053574cf2b13be497dc93a7ae
11 N90876a8ecd5e4c5682f60fae425f5137
12 Nabb10f3bc18949f0a1cfee09eda7cb59
13 Ncf6801714e4344cca3deddeab81f7da2
14 Ne8a70c385ba048eea690c6be133d8ca4
15 Neeaefb245c164bf9b99659aee10a7a6e
16 Nfce5f49c302846628bc9cbc12195c9b7
17 Nfdc2396cd8ea4a13ac38bdba54009b13
18 anzsrc-for:11
19 anzsrc-for:1109
20 schema:author N9db8a5bfe192408a9d4c01d5cde12e90
21 schema:citation sg:pub.10.1007/bf00999391
22 sg:pub.10.1007/bf00999694
23 https://app.dimensions.ai/details/publication/pub.1076155626
24 https://app.dimensions.ai/details/publication/pub.1076750128
25 https://app.dimensions.ai/details/publication/pub.1078281641
26 https://app.dimensions.ai/details/publication/pub.1079021792
27 https://app.dimensions.ai/details/publication/pub.1079033956
28 https://app.dimensions.ai/details/publication/pub.1079247873
29 https://app.dimensions.ai/details/publication/pub.1079733111
30 https://app.dimensions.ai/details/publication/pub.1080219994
31 https://app.dimensions.ai/details/publication/pub.1082619943
32 https://app.dimensions.ai/details/publication/pub.1082866369
33 https://doi.org/10.1006/abbi.1993.1189
34 https://doi.org/10.1016/0003-2697(78)90342-1
35 https://doi.org/10.1016/0005-2736(89)90210-1
36 https://doi.org/10.1016/0006-8993(77)90152-4
37 https://doi.org/10.1016/0009-3084(90)90145-h
38 https://doi.org/10.1016/0024-3205(85)90606-x
39 https://doi.org/10.1016/0031-9384(86)90285-4
40 https://doi.org/10.1016/0031-9384(90)90295-f
41 https://doi.org/10.1016/0304-3940(89)90217-6
42 https://doi.org/10.1016/0304-3940(93)90085-y
43 https://doi.org/10.1016/s0006-291x(77)80151-4
44 https://doi.org/10.1016/s0300-595x(76)80040-0
45 https://doi.org/10.1016/s0940-2993(11)80224-1
46 https://doi.org/10.1055/s-2007-1003614
47 https://doi.org/10.1055/s-2007-1003626
48 https://doi.org/10.1111/j.1471-4159.1976.tb01562.x
49 https://doi.org/10.1111/j.1471-4159.1978.tb00107.x
50 https://doi.org/10.1111/j.1471-4159.1988.tb02462.x
51 https://doi.org/10.1136/jcp.15.4.374
52 https://doi.org/10.1136/jcp.22.2.246-b
53 https://doi.org/10.1139/y77-025
54 https://doi.org/10.1152/jappl.1988.64.4.1333
55 https://doi.org/10.2337/diab.36.2.169
56 https://doi.org/10.7326/0003-4819-88-5-671
57 schema:datePublished 1996-04
58 schema:datePublishedReg 1996-04-01
59 schema:description The level of malondialdehyde (MDA), an index of lipid peroxidation, and the antioxidants superoxide dismutase (SOD) and glutathione (GSH), as well as the activity of Na+, K(+)-ATPase, were assessed in whole rat brain after immobilization, anemic hypoxia (NaNO2) and 72 h starvation. The effect of these stressors on plasma glucose and corticosterone levels was also observed. Hypoxia and starvation stimulated the lipid peroxide formation in brain as indicated by an increase in the level of MDA, being higher after starvation than hypoxia. Brain SOD activity was also increased in response to hypoxia and starvation while GSH content was only diminished in hypoxia. However, neither MDA nor antioxidants were affected by immobilization. On the other hand, the activity of brain Na+, K(+)-ATPase was significantly increased by immobilization and hypoxia but decreased in starvation. A similar pattern of change was also observed in plasma glucose and corticosterone levels in response to these stressors. These results elucidate differences in the biochemical response of animals towards various types of stress, with increased lipid peroxide formation in hypoxia and starvation.
60 schema:genre research_article
61 schema:inLanguage en
62 schema:isAccessibleForFree false
63 schema:isPartOf Nd21d563811a244228333a4b5b3f087a5
64 Ne47663240ae04f58b10b6b58c861e6ee
65 sg:journal.1295005
66 schema:name Effect of various stressors on the levels of lipid peroxide, antioxidants and Na+, K+-ATPase actrivity in rat brain
67 schema:pagination 336-339
68 schema:productId N1511ac156bf6493898a89dc46217988f
69 N42f9ebf8d8ac4222ad95bbd5011c5fce
70 N8cd119eded1240e3bb6ada1049c4b303
71 Ne21a5b43f94342308a9f87e21b6579ea
72 Nf51bfda7f73d47deb69f7200184e7a71
73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038881441
74 https://doi.org/10.1007/bf01919536
75 schema:sdDatePublished 2019-04-11T00:13
76 schema:sdLicense https://scigraph.springernature.com/explorer/license/
77 schema:sdPublisher N27fffe03584d46de92f8b8a268d1a1c9
78 schema:url http://link.springer.com/10.1007/BF01919536
79 sgo:license sg:explorer/license/
80 sgo:sdDataset articles
81 rdf:type schema:ScholarlyArticle
82 N0092b19de93444578dfcb4673429d590 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Glutathione
84 rdf:type schema:DefinedTerm
85 N0415a45f5b74428b87cc4eca336a00d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Antioxidants
87 rdf:type schema:DefinedTerm
88 N0a702de141e14e2393c5718d63f36b6f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Rats
90 rdf:type schema:DefinedTerm
91 N0b53582cace3442385d997ba8bd98087 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Lipid Peroxidation
93 rdf:type schema:DefinedTerm
94 N120c924384d247778784d545040a8493 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Malondialdehyde
96 rdf:type schema:DefinedTerm
97 N1511ac156bf6493898a89dc46217988f schema:name readcube_id
98 schema:value b9360d2a895bf2780830d44f52629ca1d23acfcedbf277953194fdbfc8924e60
99 rdf:type schema:PropertyValue
100 N27fffe03584d46de92f8b8a268d1a1c9 schema:name Springer Nature - SN SciGraph project
101 rdf:type schema:Organization
102 N289a686fde774e179855e8d77b7d86b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Male
104 rdf:type schema:DefinedTerm
105 N344fe656dcbb448ab43550052f2977e9 rdf:first sg:person.0615762501.20
106 rdf:rest rdf:nil
107 N39caf5e0317748f5aafb5ffe99098fc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Hypoxia
109 rdf:type schema:DefinedTerm
110 N411893f40ea9488ba67872ed55ebd296 rdf:first sg:person.01254572024.81
111 rdf:rest N344fe656dcbb448ab43550052f2977e9
112 N42f9ebf8d8ac4222ad95bbd5011c5fce schema:name nlm_unique_id
113 schema:value 0376547
114 rdf:type schema:PropertyValue
115 N5839f2fa293b4c118bb3ea267d216627 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Rats, Wistar
117 rdf:type schema:DefinedTerm
118 N624b2efc471642e99bc5d0e2fd017e60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Superoxide Dismutase
120 rdf:type schema:DefinedTerm
121 N8cb0f8f053574cf2b13be497dc93a7ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Sodium-Potassium-Exchanging ATPase
123 rdf:type schema:DefinedTerm
124 N8cd119eded1240e3bb6ada1049c4b303 schema:name dimensions_id
125 schema:value pub.1038881441
126 rdf:type schema:PropertyValue
127 N90876a8ecd5e4c5682f60fae425f5137 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Animals
129 rdf:type schema:DefinedTerm
130 N9db8a5bfe192408a9d4c01d5cde12e90 rdf:first sg:person.0603467660.31
131 rdf:rest N411893f40ea9488ba67872ed55ebd296
132 Nabb10f3bc18949f0a1cfee09eda7cb59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Restraint, Physical
134 rdf:type schema:DefinedTerm
135 Ncf6801714e4344cca3deddeab81f7da2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Brain
137 rdf:type schema:DefinedTerm
138 Nd21d563811a244228333a4b5b3f087a5 schema:volumeNumber 52
139 rdf:type schema:PublicationVolume
140 Ne21a5b43f94342308a9f87e21b6579ea schema:name doi
141 schema:value 10.1007/bf01919536
142 rdf:type schema:PropertyValue
143 Ne47663240ae04f58b10b6b58c861e6ee schema:issueNumber 4
144 rdf:type schema:PublicationIssue
145 Ne8a70c385ba048eea690c6be133d8ca4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Stress, Physiological
147 rdf:type schema:DefinedTerm
148 Neeaefb245c164bf9b99659aee10a7a6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Blood Glucose
150 rdf:type schema:DefinedTerm
151 Nf51bfda7f73d47deb69f7200184e7a71 schema:name pubmed_id
152 schema:value 8620936
153 rdf:type schema:PropertyValue
154 Nfce5f49c302846628bc9cbc12195c9b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Corticosterone
156 rdf:type schema:DefinedTerm
157 Nfdc2396cd8ea4a13ac38bdba54009b13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Starvation
159 rdf:type schema:DefinedTerm
160 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
161 schema:name Medical and Health Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
164 schema:name Neurosciences
165 rdf:type schema:DefinedTerm
166 sg:journal.1295005 schema:issn 1420-682X
167 1420-9071
168 schema:name Cellular and Molecular Life Sciences
169 rdf:type schema:Periodical
170 sg:person.01254572024.81 schema:affiliation https://www.grid.ac/institutes/grid.7776.1
171 schema:familyName Abd El-Fattah
172 schema:givenName A. A.
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254572024.81
174 rdf:type schema:Person
175 sg:person.0603467660.31 schema:affiliation https://www.grid.ac/institutes/grid.7776.1
176 schema:familyName Shaheen
177 schema:givenName A. A.
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603467660.31
179 rdf:type schema:Person
180 sg:person.0615762501.20 schema:affiliation https://www.grid.ac/institutes/grid.7776.1
181 schema:familyName Gad
182 schema:givenName M. Z.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615762501.20
184 rdf:type schema:Person
185 sg:pub.10.1007/bf00999391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030099229
186 https://doi.org/10.1007/bf00999391
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/bf00999694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029323126
189 https://doi.org/10.1007/bf00999694
190 rdf:type schema:CreativeWork
191 https://app.dimensions.ai/details/publication/pub.1076155626 schema:CreativeWork
192 https://app.dimensions.ai/details/publication/pub.1076750128 schema:CreativeWork
193 https://app.dimensions.ai/details/publication/pub.1078281641 schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1079021792 schema:CreativeWork
195 https://app.dimensions.ai/details/publication/pub.1079033956 schema:CreativeWork
196 https://app.dimensions.ai/details/publication/pub.1079247873 schema:CreativeWork
197 https://app.dimensions.ai/details/publication/pub.1079733111 schema:CreativeWork
198 https://app.dimensions.ai/details/publication/pub.1080219994 schema:CreativeWork
199 https://app.dimensions.ai/details/publication/pub.1082619943 schema:CreativeWork
200 https://app.dimensions.ai/details/publication/pub.1082866369 schema:CreativeWork
201 https://doi.org/10.1006/abbi.1993.1189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001771289
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/0003-2697(78)90342-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003753168
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/0005-2736(89)90210-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021177561
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/0006-8993(77)90152-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046002639
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/0009-3084(90)90145-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1004736199
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/0024-3205(85)90606-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040823958
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/0031-9384(86)90285-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039567881
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/0031-9384(90)90295-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1030295229
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/0304-3940(89)90217-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003555610
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/0304-3940(93)90085-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1040449013
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/s0006-291x(77)80151-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036311868
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/s0300-595x(76)80040-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037673112
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/s0940-2993(11)80224-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052211579
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1055/s-2007-1003614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057478193
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1055/s-2007-1003626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057478205
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1111/j.1471-4159.1976.tb01562.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050742707
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1111/j.1471-4159.1978.tb00107.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032811744
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1111/j.1471-4159.1988.tb02462.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027883512
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1136/jcp.15.4.374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017856973
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1136/jcp.22.2.246-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1020960118
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1139/y77-025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050012851
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1152/jappl.1988.64.4.1333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079713227
244 rdf:type schema:CreativeWork
245 https://doi.org/10.2337/diab.36.2.169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070735201
246 rdf:type schema:CreativeWork
247 https://doi.org/10.7326/0003-4819-88-5-671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073735561
248 rdf:type schema:CreativeWork
249 https://www.grid.ac/institutes/grid.7776.1 schema:alternateName Cairo University
250 schema:name Department of Bichemistry, Faculty of Pharmacy, Cairo University, Cairo, (Egypt)
251 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...