Cirrhosis: Diagnosis by liver surface analysis with high-frequency ultrasound View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-12

AUTHORS

Hector Ferral, Rene Male, Mario Cardiel, Luis Munoz, Francisco Quiroz y Ferrari

ABSTRACT

To determine the sensitivity, specificity, and predictive values of the sonographic analysis of liver surface irregularities for the diagnosis of cirrhosis, the authors conducted a prospective and blinded study in 70 subjects with abnormal liver function tests. All patients included underwent liver biopsy within 15 days of the sonographic study. Twenty-three subjects with no signs or symptoms of liver disease were examined to assess the sonographic appearance of normal liver surface. Studies were performed with a small-parts probe, high-frequency transducer (7.5 MHz). Three basic patterns of liver surface were found: type I, normal; type II, focal abnormality; and type III, diffuse irregularity. Considering diffuse surface irregularity as an objective sonographic sign of cirrhosis, the study's sensitivity was 87.5%, specificity 81.5%, and positive and negative predictive values were 80% and 88.5%, respectively. Disease prevalence for cirrhosis was 45%. We conclude that sonographic analysis of the liver surface is a useful noninvasive test for the diagnosis of cirrhosis in the appropriate clinical setting. More... »

PAGES

74-78

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01888512

DOI

http://dx.doi.org/10.1007/bf01888512

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019954667

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1544561


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220 Department of Gastroenterology, Instituto Nacional de la Nutricion, Mexico D.F., Mexico
221 Department of Pathology, Instituto Nacional de la Nutricion, Mexico D.F., Mexico
222 Department of Radiology, Instituto Nacional de la Nutricion, Mexico D.F., Mexico
223 rdf:type schema:Organization
 




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