Possible reduction of surface charge by a mutation inParamecium tetraurelia View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-10

AUTHORS

Youko Satow, Ching Kung

ABSTRACT

Under voltage clamp, a mutant of Paramecium tetraurelia (teaB) shows a shift in the positive direction of the voltage sensitivity of the Ca conductance and the depolarization inactivation curve by 10 mV with no change in the total conductance. This effect can be mimicked in the wild type by the addition of external CA2+ or Mg2+. The mutation also shifts the resting potential and the voltage sensitivities of the delayed rectification (depolarization-sensitive) K conductance and the anomalous rectification (hyperpolarization-sensitive) K conductance in the positive direction to a similar extent. This systematic shift of channel voltage sensitivities is best explained by the reduction of the surface negative charges of the membrane due to the mutation. More... »

PAGES

179-190

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01875424

DOI

http://dx.doi.org/10.1007/bf01875424

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048848814

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6264086


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