Comparison of nonelectrolyte permeability patterns in several epithelia View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1972-12

AUTHORS

Dickson J. Hingson, Jared M. Diamond

ABSTRACT

Reflection coefficients (σ's) have been determined for 13 to 36 non-electrolytes in goldfish gallbladder, bullfrog gallbladder, bullfrog intestine, and guineapig intestine. These results have been compared with the results of similar previous studies in rabbit gallbladder, bullfrog choroid plexus, and guinea-pig gallbladder to determine types of species variation, organ variation, and individual variation. Two principal types of variation were established: (1) Branched solutes are much less permeant than straight-chain analogues in gallbladders of all four species studied, whereas this effect is small in intestine and negligible in choroid plexus. This variation in degree of discrimination against branched solutes is attributed to variation in closeness of packing of membrane lipids. (2) In certain epithelia, small polar solutes are more permeant than expected from their bulk nonpolar-solvent/water partition coefficients and from their size. This feature is very marked in rabbit gallbladder, somewhat marked in guineapig gallbladder and intestine and in bullfrog choroid plexus, apparent mainly just for formamide (the smallest polar nonelectrolyte) in bullfrog intestine, and virtually absent in goldfish and bullfrog gallbladders. Analysis of individual variability in preparations of guinea-pig intestine and rabbit gallbladder from different animals shows covariation in σ's of small polar nonelectrolytes uncorrelated with variation in σ's of other solutes. Small polar solutes, in epithelia where their permeability is as expected from size and from nonpolar-solvent/water partition coefficients, resemble other solutes in having markedly temperature-dependent σ's (high apparent activation energies of permeation), but have nearly temperature-independent σ's (low activation energies, as for diffusion in aqueous solution) in epithelia where their permeability is enhanced. These findings suggest that additional size-restricted permeation pathways by-passing membrane lipid (“pores”) are present in some tissues and smaller or virtually absent in others. More... »

PAGES

93-135

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01867849

DOI

http://dx.doi.org/10.1007/bf01867849

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006889262

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4544408


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anura", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cyprinidae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diffusion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epithelium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gallbladder", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastric Mucosa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Guinea Pigs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrogen-Ion Concentration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestinal Mucosa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kinetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lipids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mathematics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Potentials", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organ Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osmolar Concentration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Permeability", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rabbits", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rana catesbeiana", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Solutions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Species Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Structure-Activity Relationship", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sucrose", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Temperature", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Physiology Department, University of California Medical Center, 90024, Los Angeles, California", 
          "id": "http://www.grid.ac/institutes/grid.413083.d", 
          "name": [
            "Physiology Department, University of California Medical Center, 90024, Los Angeles, California"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hingson", 
        "givenName": "Dickson J.", 
        "id": "sg:person.053661006.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053661006.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Physiology Department, University of California Medical Center, 90024, Los Angeles, California", 
          "id": "http://www.grid.ac/institutes/grid.413083.d", 
          "name": [
            "Physiology Department, University of California Medical Center, 90024, Los Angeles, California"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Diamond", 
        "givenName": "Jared M.", 
        "id": "sg:person.01207601043.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207601043.08"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01948814", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031219697", 
          "https://doi.org/10.1007/bf01948814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01957348", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001520547", 
          "https://doi.org/10.1007/bf01957348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01869776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031584029", 
          "https://doi.org/10.1007/bf01869776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01869856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035935567", 
          "https://doi.org/10.1007/bf01869856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02038800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052562232", 
          "https://doi.org/10.1007/bf02038800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01868010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006807063", 
          "https://doi.org/10.1007/bf01868010"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/224240a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032100697", 
          "https://doi.org/10.1038/224240a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01867914", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052527973", 
          "https://doi.org/10.1007/bf01867914"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01869781", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039734665", 
          "https://doi.org/10.1007/bf01869781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01867915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034701394", 
          "https://doi.org/10.1007/bf01867915"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1972-12", 
    "datePublishedReg": "1972-12-01", 
    "description": "Reflection coefficients (\u03c3's) have been determined for 13 to 36 non-electrolytes in goldfish gallbladder, bullfrog gallbladder, bullfrog intestine, and guineapig intestine. These results have been compared with the results of similar previous studies in rabbit gallbladder, bullfrog choroid plexus, and guinea-pig gallbladder to determine types of species variation, organ variation, and individual variation. Two principal types of variation were established: (1) Branched solutes are much less permeant than straight-chain analogues in gallbladders of all four species studied, whereas this effect is small in intestine and negligible in choroid plexus. This variation in degree of discrimination against branched solutes is attributed to variation in closeness of packing of membrane lipids. (2) In certain epithelia, small polar solutes are more permeant than expected from their bulk nonpolar-solvent/water partition coefficients and from their size. This feature is very marked in rabbit gallbladder, somewhat marked in guineapig gallbladder and intestine and in bullfrog choroid plexus, apparent mainly just for formamide (the smallest polar nonelectrolyte) in bullfrog intestine, and virtually absent in goldfish and bullfrog gallbladders. Analysis of individual variability in preparations of guinea-pig intestine and rabbit gallbladder from different animals shows covariation in \u03c3's of small polar nonelectrolytes uncorrelated with variation in \u03c3's of other solutes. Small polar solutes, in epithelia where their permeability is as expected from size and from nonpolar-solvent/water partition coefficients, resemble other solutes in having markedly temperature-dependent \u03c3's (high apparent activation energies of permeation), but have nearly temperature-independent \u03c3's (low activation energies, as for diffusion in aqueous solution) in epithelia where their permeability is enhanced. These findings suggest that additional size-restricted permeation pathways by-passing membrane lipid (\u201cpores\u201d) are present in some tissues and smaller or virtually absent in others.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf01867849", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1012006", 
        "issn": [
          "0022-2631", 
          "1432-1424"
        ], 
        "name": "The Journal of Membrane Biology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "keywords": [
      "membrane lipids", 
      "species variation", 
      "small polar solutes", 
      "permeation pathway", 
      "certain epithelia", 
      "different animals", 
      "individual variation", 
      "organ variation", 
      "closeness of packing", 
      "lipids", 
      "epithelium", 
      "choroid plexus", 
      "species", 
      "intestine", 
      "less permeant", 
      "pathway", 
      "variation", 
      "degree of discrimination", 
      "straight-chain analogues", 
      "covariation", 
      "previous studies", 
      "rabbit gallbladder", 
      "individual variability", 
      "water partition coefficient", 
      "goldfish", 
      "permeant", 
      "tissue", 
      "animals", 
      "solutes", 
      "patterns", 
      "types", 
      "size", 
      "principal types", 
      "variability", 
      "permeability", 
      "analogues", 
      "analysis", 
      "results", 
      "polar solutes", 
      "findings", 
      "effect", 
      "study", 
      "plexus", 
      "guinea pig intestine", 
      "discrimination", 
      "features", 
      "comparison", 
      "packing", 
      "partition coefficients", 
      "similar previous studies", 
      "degree", 
      "permeability patterns", 
      "preparation", 
      "formamide", 
      "closeness", 
      "nonelectrolytes", 
      "gallbladder", 
      "guinea pig gallbladder", 
      "coefficient", 
      "reflection coefficient", 
      "polar nonelectrolytes"
    ], 
    "name": "Comparison of nonelectrolyte permeability patterns in several epithelia", 
    "pagination": "93-135", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006889262"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01867849"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "4544408"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01867849", 
      "https://app.dimensions.ai/details/publication/pub.1006889262"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T16:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_114.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf01867849"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01867849'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01867849'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01867849'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01867849'


 

This table displays all metadata directly associated to this object as RDF triples.

269 TRIPLES      21 PREDICATES      122 URIs      104 LITERALS      32 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01867849 schema:about N06db18e4b4bf40d8be350c1f59eb08ef
2 N2bc20bbcf52c46b6b9c92f36ccaa462e
3 N35e9ac0997b649afb4010de7e357077b
4 N424d567dbaaa4242bc37f206e44d2cfd
5 N463a5319d7d04061b4276d33e03c332d
6 N46bd50bab75e436aba72cf7273c08ae0
7 N5abb78633dd84740b8a9baacaa063f76
8 N5cc865105209442090b51537357f789f
9 N6068cf6a2e914204b305c81162f58e0a
10 N6cee73359e6e4b92bb26799c86c45dea
11 N70bbc96392b245f7944304fb3b51301a
12 N70dbf52b7bac4c79957e0f91bb7d344c
13 N748301663ff14a438f42a6f62ab3030f
14 N7e1d7e8b3e9542aaa48756baac57d6bd
15 N907760ce47964c33a3c558f307505e90
16 Naccf8761d4b246398c9521da4410e176
17 Nbd7d17b04337420aab1fbb08ec34bcc1
18 Nc90dd00a8e0446d5a3d11ef19e1034ab
19 Nc91ad6c907244ee8b0499debc1248b73
20 Ncefa07f3c6174e9a841020a4706777b0
21 Nd8dc3cab93d84f009ca09cea5de442e2
22 Nda4606ab5d7e4c86a116fd0a9b087ff4
23 Ndda32d456d074e0f83cef0dc524187d9
24 Nddcd9de8c20d4392aacfd9318db852a6
25 Nde94c195e0e24b1cab1e8d8da6e0097e
26 anzsrc-for:11
27 anzsrc-for:1109
28 schema:author N34b61a18a0ea498880a188a230b57e26
29 schema:citation sg:pub.10.1007/bf01867914
30 sg:pub.10.1007/bf01867915
31 sg:pub.10.1007/bf01868010
32 sg:pub.10.1007/bf01869776
33 sg:pub.10.1007/bf01869781
34 sg:pub.10.1007/bf01869856
35 sg:pub.10.1007/bf01948814
36 sg:pub.10.1007/bf01957348
37 sg:pub.10.1007/bf02038800
38 sg:pub.10.1038/224240a0
39 schema:datePublished 1972-12
40 schema:datePublishedReg 1972-12-01
41 schema:description Reflection coefficients (σ's) have been determined for 13 to 36 non-electrolytes in goldfish gallbladder, bullfrog gallbladder, bullfrog intestine, and guineapig intestine. These results have been compared with the results of similar previous studies in rabbit gallbladder, bullfrog choroid plexus, and guinea-pig gallbladder to determine types of species variation, organ variation, and individual variation. Two principal types of variation were established: (1) Branched solutes are much less permeant than straight-chain analogues in gallbladders of all four species studied, whereas this effect is small in intestine and negligible in choroid plexus. This variation in degree of discrimination against branched solutes is attributed to variation in closeness of packing of membrane lipids. (2) In certain epithelia, small polar solutes are more permeant than expected from their bulk nonpolar-solvent/water partition coefficients and from their size. This feature is very marked in rabbit gallbladder, somewhat marked in guineapig gallbladder and intestine and in bullfrog choroid plexus, apparent mainly just for formamide (the smallest polar nonelectrolyte) in bullfrog intestine, and virtually absent in goldfish and bullfrog gallbladders. Analysis of individual variability in preparations of guinea-pig intestine and rabbit gallbladder from different animals shows covariation in σ's of small polar nonelectrolytes uncorrelated with variation in σ's of other solutes. Small polar solutes, in epithelia where their permeability is as expected from size and from nonpolar-solvent/water partition coefficients, resemble other solutes in having markedly temperature-dependent σ's (high apparent activation energies of permeation), but have nearly temperature-independent σ's (low activation energies, as for diffusion in aqueous solution) in epithelia where their permeability is enhanced. These findings suggest that additional size-restricted permeation pathways by-passing membrane lipid (“pores”) are present in some tissues and smaller or virtually absent in others.
42 schema:genre article
43 schema:isAccessibleForFree false
44 schema:isPartOf N1475f95884854592b009b926cbbeedca
45 Ndae76f32a0224cf6917235368e48cca5
46 sg:journal.1012006
47 schema:keywords analogues
48 analysis
49 animals
50 certain epithelia
51 choroid plexus
52 closeness
53 closeness of packing
54 coefficient
55 comparison
56 covariation
57 degree
58 degree of discrimination
59 different animals
60 discrimination
61 effect
62 epithelium
63 features
64 findings
65 formamide
66 gallbladder
67 goldfish
68 guinea pig gallbladder
69 guinea pig intestine
70 individual variability
71 individual variation
72 intestine
73 less permeant
74 lipids
75 membrane lipids
76 nonelectrolytes
77 organ variation
78 packing
79 partition coefficients
80 pathway
81 patterns
82 permeability
83 permeability patterns
84 permeant
85 permeation pathway
86 plexus
87 polar nonelectrolytes
88 polar solutes
89 preparation
90 previous studies
91 principal types
92 rabbit gallbladder
93 reflection coefficient
94 results
95 similar previous studies
96 size
97 small polar solutes
98 solutes
99 species
100 species variation
101 straight-chain analogues
102 study
103 tissue
104 types
105 variability
106 variation
107 water partition coefficient
108 schema:name Comparison of nonelectrolyte permeability patterns in several epithelia
109 schema:pagination 93-135
110 schema:productId N70d37ecc19d447f2a038461d5096deb2
111 N9889e707509c4020b4b5844c5e6c9f3f
112 N9ff545563e4e48ffb1a61d6a179f81c7
113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006889262
114 https://doi.org/10.1007/bf01867849
115 schema:sdDatePublished 2022-08-04T16:48
116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
117 schema:sdPublisher N5840a1dd07ef4a0e970d94bef3d35416
118 schema:url https://doi.org/10.1007/bf01867849
119 sgo:license sg:explorer/license/
120 sgo:sdDataset articles
121 rdf:type schema:ScholarlyArticle
122 N06db18e4b4bf40d8be350c1f59eb08ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Kinetics
124 rdf:type schema:DefinedTerm
125 N1475f95884854592b009b926cbbeedca schema:volumeNumber 10
126 rdf:type schema:PublicationVolume
127 N2bc20bbcf52c46b6b9c92f36ccaa462e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Gallbladder
129 rdf:type schema:DefinedTerm
130 N34b61a18a0ea498880a188a230b57e26 rdf:first sg:person.053661006.86
131 rdf:rest Nde2d520103d34bf190151d0f8cad986e
132 N35e9ac0997b649afb4010de7e357077b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Cyprinidae
134 rdf:type schema:DefinedTerm
135 N424d567dbaaa4242bc37f206e44d2cfd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Intestinal Mucosa
137 rdf:type schema:DefinedTerm
138 N463a5319d7d04061b4276d33e03c332d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Diffusion
140 rdf:type schema:DefinedTerm
141 N46bd50bab75e436aba72cf7273c08ae0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Guinea Pigs
143 rdf:type schema:DefinedTerm
144 N5840a1dd07ef4a0e970d94bef3d35416 schema:name Springer Nature - SN SciGraph project
145 rdf:type schema:Organization
146 N5abb78633dd84740b8a9baacaa063f76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Gastric Mucosa
148 rdf:type schema:DefinedTerm
149 N5cc865105209442090b51537357f789f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Species Specificity
151 rdf:type schema:DefinedTerm
152 N6068cf6a2e914204b305c81162f58e0a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Rabbits
154 rdf:type schema:DefinedTerm
155 N6cee73359e6e4b92bb26799c86c45dea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Structure-Activity Relationship
157 rdf:type schema:DefinedTerm
158 N70bbc96392b245f7944304fb3b51301a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Permeability
160 rdf:type schema:DefinedTerm
161 N70d37ecc19d447f2a038461d5096deb2 schema:name pubmed_id
162 schema:value 4544408
163 rdf:type schema:PropertyValue
164 N70dbf52b7bac4c79957e0f91bb7d344c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Membrane Potentials
166 rdf:type schema:DefinedTerm
167 N748301663ff14a438f42a6f62ab3030f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Osmolar Concentration
169 rdf:type schema:DefinedTerm
170 N7e1d7e8b3e9542aaa48756baac57d6bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Epithelium
172 rdf:type schema:DefinedTerm
173 N907760ce47964c33a3c558f307505e90 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Lipids
175 rdf:type schema:DefinedTerm
176 N9889e707509c4020b4b5844c5e6c9f3f schema:name doi
177 schema:value 10.1007/bf01867849
178 rdf:type schema:PropertyValue
179 N9ff545563e4e48ffb1a61d6a179f81c7 schema:name dimensions_id
180 schema:value pub.1006889262
181 rdf:type schema:PropertyValue
182 Naccf8761d4b246398c9521da4410e176 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Solutions
184 rdf:type schema:DefinedTerm
185 Nbd7d17b04337420aab1fbb08ec34bcc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Anura
187 rdf:type schema:DefinedTerm
188 Nc90dd00a8e0446d5a3d11ef19e1034ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Sucrose
190 rdf:type schema:DefinedTerm
191 Nc91ad6c907244ee8b0499debc1248b73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Time Factors
193 rdf:type schema:DefinedTerm
194 Ncefa07f3c6174e9a841020a4706777b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Organ Specificity
196 rdf:type schema:DefinedTerm
197 Nd8dc3cab93d84f009ca09cea5de442e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Mathematics
199 rdf:type schema:DefinedTerm
200 Nda4606ab5d7e4c86a116fd0a9b087ff4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
201 schema:name Rana catesbeiana
202 rdf:type schema:DefinedTerm
203 Ndae76f32a0224cf6917235368e48cca5 schema:issueNumber 1
204 rdf:type schema:PublicationIssue
205 Ndda32d456d074e0f83cef0dc524187d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Temperature
207 rdf:type schema:DefinedTerm
208 Nddcd9de8c20d4392aacfd9318db852a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
209 schema:name Hydrogen-Ion Concentration
210 rdf:type schema:DefinedTerm
211 Nde2d520103d34bf190151d0f8cad986e rdf:first sg:person.01207601043.08
212 rdf:rest rdf:nil
213 Nde94c195e0e24b1cab1e8d8da6e0097e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
214 schema:name Animals
215 rdf:type schema:DefinedTerm
216 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
217 schema:name Medical and Health Sciences
218 rdf:type schema:DefinedTerm
219 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
220 schema:name Neurosciences
221 rdf:type schema:DefinedTerm
222 sg:journal.1012006 schema:issn 0022-2631
223 1432-1424
224 schema:name The Journal of Membrane Biology
225 schema:publisher Springer Nature
226 rdf:type schema:Periodical
227 sg:person.01207601043.08 schema:affiliation grid-institutes:grid.413083.d
228 schema:familyName Diamond
229 schema:givenName Jared M.
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207601043.08
231 rdf:type schema:Person
232 sg:person.053661006.86 schema:affiliation grid-institutes:grid.413083.d
233 schema:familyName Hingson
234 schema:givenName Dickson J.
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053661006.86
236 rdf:type schema:Person
237 sg:pub.10.1007/bf01867914 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052527973
238 https://doi.org/10.1007/bf01867914
239 rdf:type schema:CreativeWork
240 sg:pub.10.1007/bf01867915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034701394
241 https://doi.org/10.1007/bf01867915
242 rdf:type schema:CreativeWork
243 sg:pub.10.1007/bf01868010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006807063
244 https://doi.org/10.1007/bf01868010
245 rdf:type schema:CreativeWork
246 sg:pub.10.1007/bf01869776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031584029
247 https://doi.org/10.1007/bf01869776
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/bf01869781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039734665
250 https://doi.org/10.1007/bf01869781
251 rdf:type schema:CreativeWork
252 sg:pub.10.1007/bf01869856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035935567
253 https://doi.org/10.1007/bf01869856
254 rdf:type schema:CreativeWork
255 sg:pub.10.1007/bf01948814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031219697
256 https://doi.org/10.1007/bf01948814
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/bf01957348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001520547
259 https://doi.org/10.1007/bf01957348
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/bf02038800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052562232
262 https://doi.org/10.1007/bf02038800
263 rdf:type schema:CreativeWork
264 sg:pub.10.1038/224240a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032100697
265 https://doi.org/10.1038/224240a0
266 rdf:type schema:CreativeWork
267 grid-institutes:grid.413083.d schema:alternateName Physiology Department, University of California Medical Center, 90024, Los Angeles, California
268 schema:name Physiology Department, University of California Medical Center, 90024, Los Angeles, California
269 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...