Estimation of epidermal growth factor receptor in 177 breast cancers: Correlation with prognostic factors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-09

AUTHORS

M. Bolla, M. Chedin, C. Souvignet, J. Marron, C. Arnould, E. Chambaz

ABSTRACT

Steroid receptors (ER, PR) and EGF-receptor were determined on 177 loco-regional primary breast cancers. Binding assay for EGF receptor was performed using a single saturating concentration of 125I-EGF incubated with membranes in the presence or absence of unlabeled EGF. With threshold values of 5 fmol/mg and 10 fmol/mg for EGF-R and steroid receptors respectively, we noted an inverse relationship between the expression of EGF-R, and ER and PR. EGF-R expression is decreased with tumor differentiation. More... »

PAGES

97-102

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01809293

DOI

http://dx.doi.org/10.1007/bf01809293

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041196596

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2176111


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