Prognostic significance of serum c-erbB-2 protein in breast cancer patients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-10

AUTHORS

Peter C. Willsher, Jayne Beaver, Sarah Pinder, Jane A. Bell, Ian O. Ellis, Roger W. Blamey, John F. R. Robertson

ABSTRACT

The tissue expression of c-erbB-2 protein in breast cancer is a marker of poor prognosis in a number of studies. More recently it has also been suggested that c-erbB-2 expression may predict response to systemic therapy in patients with advanced breast cancer. The measurement of c-erbB-2 protein in the serum of breast cancer patients has now been reported, but the significance of this finding is not clear. In this study an ELISA assay was used to measure c-erbB-2 in the sera of 23 normal controls, 46 benign breast disease patients, and 119 breast cancer patients. Elevated serum c-erbB-2 protein levels were detected in 13% (3/23) of normal controls, 15% (7/46) of benign disease patients, 15% (7/46) of Stage I/II patients, 26% (9/35) of Stage III patients, and 21% (8/38) of Stage IV patients. The tissue expression of the c-erbB-2 protein showed no association with detection of the serum c-erbB-2 protein (p = 0.31). In the 67 Stage III and IV patients who had assessable disease the presence of the c-erbB-2 protein in the serum bore no relationship to response to hormonal therapy (p = 0.71). Serum detection of the c-erbB-2 protein in Stage I/II patients predicted for a worsening of both survival outcome (p = 0.002) and disease free interval (p = 0.002). A worse outcome was also seen for the Stage III patients (p = 0.04) and Stage IV patients, although the latter did not reach statistical significance (p = 0.27). This study found that the presence of c-erbB-2 in the serum of breast cancer patients was of prognostic significance for all stages of disease. More... »

PAGES

251-255

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01806813

DOI

http://dx.doi.org/10.1007/bf01806813

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048762042

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8883967


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme-Linked Immunosorbent Assay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Staging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptor, ErbB-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reference Values", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Professorial Department of Surgery, City Hospital, Hucknall Road, NG5 1PB, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Willsher", 
        "givenName": "Peter C.", 
        "id": "sg:person.01347210454.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347210454.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Department of Histopathology, City Hospital, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beaver", 
        "givenName": "Jayne", 
        "id": "sg:person.0632072210.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632072210.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Department of Histopathology, City Hospital, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pinder", 
        "givenName": "Sarah", 
        "id": "sg:person.014576043464.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014576043464.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Department of Histopathology, City Hospital, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bell", 
        "givenName": "Jane A.", 
        "id": "sg:person.016203754172.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016203754172.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Department of Histopathology, City Hospital, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ellis", 
        "givenName": "Ian O.", 
        "id": "sg:person.01054612302.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054612302.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Professorial Department of Surgery, City Hospital, Hucknall Road, NG5 1PB, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Blamey", 
        "givenName": "Roger W.", 
        "id": "sg:person.015650304144.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015650304144.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nottingham City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412920.c", 
          "name": [
            "Professorial Department of Surgery, City Hospital, Hucknall Road, NG5 1PB, Nottingham, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robertson", 
        "givenName": "John F. R.", 
        "id": "sg:person.07764637207.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07764637207.20"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01961241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002229729", 
          "https://doi.org/10.1007/bf01961241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01212719", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005157350", 
          "https://doi.org/10.1007/bf01212719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01212719", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005157350", 
          "https://doi.org/10.1007/bf01212719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011360956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1994.387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021569604", 
          "https://doi.org/10.1038/bjc.1994.387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1994.387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021569604", 
          "https://doi.org/10.1038/bjc.1994.387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1991.101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023327364", 
          "https://doi.org/10.1038/bjc.1991.101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.1991.101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023327364", 
          "https://doi.org/10.1038/bjc.1991.101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/02841869509094014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038026586"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01961242", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045749770", 
          "https://doi.org/10.1007/bf01961242"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-8049(05)80215-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046817550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3798106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062621480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075758988", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079800982", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1996-10", 
    "datePublishedReg": "1996-10-01", 
    "description": "The tissue expression of c-erbB-2 protein in breast cancer is a marker of poor prognosis in a number of studies. More recently it has also been suggested that c-erbB-2 expression may predict response to systemic therapy in patients with advanced breast cancer. The measurement of c-erbB-2 protein in the serum of breast cancer patients has now been reported, but the significance of this finding is not clear. In this study an ELISA assay was used to measure c-erbB-2 in the sera of 23 normal controls, 46 benign breast disease patients, and 119 breast cancer patients. Elevated serum c-erbB-2 protein levels were detected in 13% (3/23) of normal controls, 15% (7/46) of benign disease patients, 15% (7/46) of Stage I/II patients, 26% (9/35) of Stage III patients, and 21% (8/38) of Stage IV patients. The tissue expression of the c-erbB-2 protein showed no association with detection of the serum c-erbB-2 protein (p = 0.31). In the 67 Stage III and IV patients who had assessable disease the presence of the c-erbB-2 protein in the serum bore no relationship to response to hormonal therapy (p = 0.71). Serum detection of the c-erbB-2 protein in Stage I/II patients predicted for a worsening of both survival outcome (p = 0.002) and disease free interval (p = 0.002). A worse outcome was also seen for the Stage III patients (p = 0.04) and Stage IV patients, although the latter did not reach statistical significance (p = 0.27). This study found that the presence of c-erbB-2 in the serum of breast cancer patients was of prognostic significance for all stages of disease.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf01806813", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1092777", 
        "issn": [
          "0167-6806", 
          "1573-7217"
        ], 
        "name": "Breast Cancer Research and Treatment", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "40"
      }
    ], 
    "name": "Prognostic significance of serum c-erbB-2 protein in breast cancer patients", 
    "pagination": "251-255", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e84b008ada7f14d3f42a1e027d2035cf39b6a61d3091bd825108c1b9e3023751"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8883967"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8111104"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01806813"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048762042"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01806813", 
      "https://app.dimensions.ai/details/publication/pub.1048762042"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113679_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF01806813"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01806813'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01806813'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01806813'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01806813'


 

This table displays all metadata directly associated to this object as RDF triples.

192 TRIPLES      21 PREDICATES      51 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01806813 schema:about N00bd42e7fed8444982d0f639b83d9bfa
2 N16e93b426f1c432dac490dc185e1965b
3 N2b015c0c751d458ca737ae0c9a27bebf
4 N2d0c93bd9bcd4987a359516c3a380d46
5 N3b9ee99b3d3f4b3cbff246b13c5aa84f
6 N875e666079944770b3b0c2843e3462bf
7 Nabfad84a3e3d459d83685f6d0c152c62
8 Naf16632ea8bf418a80fde201995c6237
9 Nd655f97defd3475baf10464d27df0cf9
10 Ne08d097e02d341cfaa1c9319add28ab4
11 Neef363ce6bd54161a15cecfb47c8eba2
12 anzsrc-for:11
13 anzsrc-for:1112
14 schema:author Ne8cf65edaecd48e1b1c02d14c08bb12a
15 schema:citation sg:pub.10.1007/bf01212719
16 sg:pub.10.1007/bf01961241
17 sg:pub.10.1007/bf01961242
18 sg:pub.10.1038/bjc.1991.101
19 sg:pub.10.1038/bjc.1994.387
20 https://app.dimensions.ai/details/publication/pub.1075758988
21 https://app.dimensions.ai/details/publication/pub.1079800982
22 https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f
23 https://doi.org/10.1016/s0959-8049(05)80215-1
24 https://doi.org/10.1126/science.3798106
25 https://doi.org/10.3109/02841869509094014
26 schema:datePublished 1996-10
27 schema:datePublishedReg 1996-10-01
28 schema:description The tissue expression of c-erbB-2 protein in breast cancer is a marker of poor prognosis in a number of studies. More recently it has also been suggested that c-erbB-2 expression may predict response to systemic therapy in patients with advanced breast cancer. The measurement of c-erbB-2 protein in the serum of breast cancer patients has now been reported, but the significance of this finding is not clear. In this study an ELISA assay was used to measure c-erbB-2 in the sera of 23 normal controls, 46 benign breast disease patients, and 119 breast cancer patients. Elevated serum c-erbB-2 protein levels were detected in 13% (3/23) of normal controls, 15% (7/46) of benign disease patients, 15% (7/46) of Stage I/II patients, 26% (9/35) of Stage III patients, and 21% (8/38) of Stage IV patients. The tissue expression of the c-erbB-2 protein showed no association with detection of the serum c-erbB-2 protein (p = 0.31). In the 67 Stage III and IV patients who had assessable disease the presence of the c-erbB-2 protein in the serum bore no relationship to response to hormonal therapy (p = 0.71). Serum detection of the c-erbB-2 protein in Stage I/II patients predicted for a worsening of both survival outcome (p = 0.002) and disease free interval (p = 0.002). A worse outcome was also seen for the Stage III patients (p = 0.04) and Stage IV patients, although the latter did not reach statistical significance (p = 0.27). This study found that the presence of c-erbB-2 in the serum of breast cancer patients was of prognostic significance for all stages of disease.
29 schema:genre research_article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf N64e66067daed4b5a83d670660e4cab10
33 N69babde5f2b741f8b7fb31a17ae13902
34 sg:journal.1092777
35 schema:name Prognostic significance of serum c-erbB-2 protein in breast cancer patients
36 schema:pagination 251-255
37 schema:productId N1e39a17c15f24a23b8105c45e1a1c9b8
38 N4da341e9ee3949dd86077a83549e116d
39 N6d7724e182f64a0fb177dd26c7b04c4e
40 N79ebce7cbabf4226ab6b420d937dd7db
41 Ned7e3e442e9f447da469ce0bc3f1f5a5
42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048762042
43 https://doi.org/10.1007/bf01806813
44 schema:sdDatePublished 2019-04-11T10:39
45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
46 schema:sdPublisher Nc630ae47454f4b8e94f8823b8e00e293
47 schema:url http://link.springer.com/10.1007/BF01806813
48 sgo:license sg:explorer/license/
49 sgo:sdDataset articles
50 rdf:type schema:ScholarlyArticle
51 N00bd42e7fed8444982d0f639b83d9bfa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
52 schema:name Breast Neoplasms
53 rdf:type schema:DefinedTerm
54 N16e93b426f1c432dac490dc185e1965b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
55 schema:name Neoplasm Staging
56 rdf:type schema:DefinedTerm
57 N1e39a17c15f24a23b8105c45e1a1c9b8 schema:name readcube_id
58 schema:value e84b008ada7f14d3f42a1e027d2035cf39b6a61d3091bd825108c1b9e3023751
59 rdf:type schema:PropertyValue
60 N2b015c0c751d458ca737ae0c9a27bebf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Reference Values
62 rdf:type schema:DefinedTerm
63 N2d0c93bd9bcd4987a359516c3a380d46 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Receptor, ErbB-2
65 rdf:type schema:DefinedTerm
66 N33b2acee897b43c9ac74e76239a702f1 rdf:first sg:person.016203754172.26
67 rdf:rest N703986352da746bda6a517b505256721
68 N3b9ee99b3d3f4b3cbff246b13c5aa84f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Humans
70 rdf:type schema:DefinedTerm
71 N4aca5cef86494a30a086a4f1aad4374e rdf:first sg:person.0632072210.15
72 rdf:rest N7ac59a0735cb4f0f9fc9fc5ac3e22ed5
73 N4da341e9ee3949dd86077a83549e116d schema:name pubmed_id
74 schema:value 8883967
75 rdf:type schema:PropertyValue
76 N520437074e93404889d81944fb65892e rdf:first sg:person.07764637207.20
77 rdf:rest rdf:nil
78 N64e66067daed4b5a83d670660e4cab10 schema:issueNumber 3
79 rdf:type schema:PublicationIssue
80 N69babde5f2b741f8b7fb31a17ae13902 schema:volumeNumber 40
81 rdf:type schema:PublicationVolume
82 N6d7724e182f64a0fb177dd26c7b04c4e schema:name doi
83 schema:value 10.1007/bf01806813
84 rdf:type schema:PropertyValue
85 N703986352da746bda6a517b505256721 rdf:first sg:person.01054612302.65
86 rdf:rest Nc2f0e263634a441c8de890754ac9e481
87 N79ebce7cbabf4226ab6b420d937dd7db schema:name nlm_unique_id
88 schema:value 8111104
89 rdf:type schema:PropertyValue
90 N7ac59a0735cb4f0f9fc9fc5ac3e22ed5 rdf:first sg:person.014576043464.09
91 rdf:rest N33b2acee897b43c9ac74e76239a702f1
92 N875e666079944770b3b0c2843e3462bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Female
94 rdf:type schema:DefinedTerm
95 Nabfad84a3e3d459d83685f6d0c152c62 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Breast Diseases
97 rdf:type schema:DefinedTerm
98 Naf16632ea8bf418a80fde201995c6237 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Enzyme-Linked Immunosorbent Assay
100 rdf:type schema:DefinedTerm
101 Nc2f0e263634a441c8de890754ac9e481 rdf:first sg:person.015650304144.58
102 rdf:rest N520437074e93404889d81944fb65892e
103 Nc630ae47454f4b8e94f8823b8e00e293 schema:name Springer Nature - SN SciGraph project
104 rdf:type schema:Organization
105 Nd655f97defd3475baf10464d27df0cf9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Prognosis
107 rdf:type schema:DefinedTerm
108 Ne08d097e02d341cfaa1c9319add28ab4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Neoplasm Proteins
110 rdf:type schema:DefinedTerm
111 Ne8cf65edaecd48e1b1c02d14c08bb12a rdf:first sg:person.01347210454.77
112 rdf:rest N4aca5cef86494a30a086a4f1aad4374e
113 Ned7e3e442e9f447da469ce0bc3f1f5a5 schema:name dimensions_id
114 schema:value pub.1048762042
115 rdf:type schema:PropertyValue
116 Neef363ce6bd54161a15cecfb47c8eba2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Biomarkers, Tumor
118 rdf:type schema:DefinedTerm
119 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
120 schema:name Medical and Health Sciences
121 rdf:type schema:DefinedTerm
122 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
123 schema:name Oncology and Carcinogenesis
124 rdf:type schema:DefinedTerm
125 sg:journal.1092777 schema:issn 0167-6806
126 1573-7217
127 schema:name Breast Cancer Research and Treatment
128 rdf:type schema:Periodical
129 sg:person.01054612302.65 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
130 schema:familyName Ellis
131 schema:givenName Ian O.
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054612302.65
133 rdf:type schema:Person
134 sg:person.01347210454.77 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
135 schema:familyName Willsher
136 schema:givenName Peter C.
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347210454.77
138 rdf:type schema:Person
139 sg:person.014576043464.09 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
140 schema:familyName Pinder
141 schema:givenName Sarah
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014576043464.09
143 rdf:type schema:Person
144 sg:person.015650304144.58 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
145 schema:familyName Blamey
146 schema:givenName Roger W.
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015650304144.58
148 rdf:type schema:Person
149 sg:person.016203754172.26 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
150 schema:familyName Bell
151 schema:givenName Jane A.
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016203754172.26
153 rdf:type schema:Person
154 sg:person.0632072210.15 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
155 schema:familyName Beaver
156 schema:givenName Jayne
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632072210.15
158 rdf:type schema:Person
159 sg:person.07764637207.20 schema:affiliation https://www.grid.ac/institutes/grid.412920.c
160 schema:familyName Robertson
161 schema:givenName John F. R.
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07764637207.20
163 rdf:type schema:Person
164 sg:pub.10.1007/bf01212719 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005157350
165 https://doi.org/10.1007/bf01212719
166 rdf:type schema:CreativeWork
167 sg:pub.10.1007/bf01961241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002229729
168 https://doi.org/10.1007/bf01961241
169 rdf:type schema:CreativeWork
170 sg:pub.10.1007/bf01961242 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045749770
171 https://doi.org/10.1007/bf01961242
172 rdf:type schema:CreativeWork
173 sg:pub.10.1038/bjc.1991.101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023327364
174 https://doi.org/10.1038/bjc.1991.101
175 rdf:type schema:CreativeWork
176 sg:pub.10.1038/bjc.1994.387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021569604
177 https://doi.org/10.1038/bjc.1994.387
178 rdf:type schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1075758988 schema:CreativeWork
180 https://app.dimensions.ai/details/publication/pub.1079800982 schema:CreativeWork
181 https://doi.org/10.1002/1097-0142(197703)39:3<1289::aid-cncr2820390340>3.0.co;2-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1011360956
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/s0959-8049(05)80215-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046817550
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1126/science.3798106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062621480
186 rdf:type schema:CreativeWork
187 https://doi.org/10.3109/02841869509094014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038026586
188 rdf:type schema:CreativeWork
189 https://www.grid.ac/institutes/grid.412920.c schema:alternateName Nottingham City Hospital
190 schema:name Department of Histopathology, City Hospital, Nottingham, UK
191 Professorial Department of Surgery, City Hospital, Hucknall Road, NG5 1PB, Nottingham, UK
192 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...