Epidermal growth factor receptors in human breast cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-09

AUTHORS

Rolando Pérez, María Pascual, Amparo Macías, Agustín Lage

ABSTRACT

The capacity for specific binding of125I-epidermal growth factor (EGF) was studied in crude membrane fractions from 95 human breast carcinomas. About 42% of the samples showed saturable, high affinity, specific binding of EGF. In 21% of the tumors we were able to demostrate high (above 10 fmoles/mg protein) binding capacity. Moreover, high EGF receptor values were associated with a low content of estradiol receptor. These studies are related to the definition of new biochemical markers in human breast cancer. More... »

PAGES

189-193

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01806484

DOI

http://dx.doi.org/10.1007/bf01806484

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019243118

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6091821


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