The phylogeny of human globin genes investigated by the maximum parsimony method View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1974-03

AUTHORS

Morris Goodman, G. William Moore, John Barnabas, Genji Matsuda

ABSTRACT

Gene phylogenetic trees were constructed by the maximum parsimony method for various sets of ninety six globin chain amino acid sequences spanning plant and animal kingdoms. The method, executed by several computer programs, constructed ancestor and descendant globin messengers on tree topologies which required the least number of nucleotide replacements to account for the evolution of the globins. The human myoglobin-hemoglobin divergence was traced to a gene duplication which occurred either in the first vertebrates or earlier yet in the common ancestor of chordates and annelids, the alpha-beta divergence to a gene duplication in the common ancestor of teleosts and tetrapods, the gamma divergence from typical beta chains to a gene duplication in basal therian mammals, and the delta separation from beta to a duplication in the basal catarrhine primates. Evidence was provided by the globin phylogenies for the hominoid affinities of the gibbon and the close phyletic relationship of the African apes to man. Over the period of teleos-tetrapod divergence the globin messengers evolved at an average rate of 18.5 nucleotide replacements per 100 codons per 108 years, a faster rate than most previous estimates. Very fast and very slow rates were encountered in different globin lineages and at different stages of descent, reducing the effectiveness of globins as molecular clocks. Rates increased with gene duplication and decreased after selection discovered useful specializations in the products of genes which had previously been freer to accept mutations. The early eutherian radiation was characterized by rapid rates of globin evolution, but the later hominoid radiation by extremely slow rates. This pattern was related to more complicated grades of internal organization evolving in human ancestors. The types of nucleotide replacements in the globin messengers over the long course of globin evolution did not seem indicative of any special mutational mechanisms. More... »

PAGES

1-48

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01795974

DOI

http://dx.doi.org/10.1007/bf01795974

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030956092

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4208305


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biological Evolution", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cetacea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chickens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Computers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fishes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Code", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Globins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haplorhini", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insecta", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Marsupialia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myoglobin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Papio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sharks", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Species Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vertebrates", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Wayne State University", 
          "id": "https://www.grid.ac/institutes/grid.254444.7", 
          "name": [
            "Department of Anatomy, Wayne State University, Medical Research Building 550 E Canfield Avenue, 48201, Detroit, Michigan, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goodman", 
        "givenName": "Morris", 
        "id": "sg:person.01023304676.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023304676.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wayne State University", 
          "id": "https://www.grid.ac/institutes/grid.254444.7", 
          "name": [
            "Department of Anatomy, Wayne State University, Medical Research Building 550 E Canfield Avenue, 48201, Detroit, Michigan, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moore", 
        "givenName": "G. William", 
        "id": "sg:person.01032646746.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032646746.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Wayne State University", 
          "id": "https://www.grid.ac/institutes/grid.254444.7", 
          "name": [
            "Department of Anatomy, Wayne State University, Medical Research Building 550 E Canfield Avenue, 48201, Detroit, Michigan, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barnabas", 
        "givenName": "John", 
        "id": "sg:person.0103050617.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0103050617.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Biochemistry, Nagasaki University, School of Medicine, Nagasaki, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuda", 
        "givenName": "Genji", 
        "id": "sg:person.073756526.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.073756526.59"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/2191335a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000685490", 
          "https://doi.org/10.1038/2191335a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10408367009027952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003291397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90327-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005183255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1961.325.1.283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005514084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90229-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005925632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90326-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007897490"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/205883a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009095762", 
          "https://doi.org/10.1038/205883a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1966.343.1.290", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009162334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1966.343.1.290", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009162334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1071/bi9710787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009300091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1030129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010582553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1030129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010582553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1970.tb01103.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012452490"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/192984a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013615981", 
          "https://doi.org/10.1038/192984a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1972.tb03437.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013698276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1972.tb03437.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013698276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-3002(62)90334-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014091196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-3002(62)90334-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014091196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/233604a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014394519", 
          "https://doi.org/10.1038/233604a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(70)90208-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015740311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(70)90208-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015740311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajpa.1330240204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015798065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajpa.1330240204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015798065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.4.5633.748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016077743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rspb.1969.0043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016830093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio232149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017261811", 
          "https://doi.org/10.1038/newbio232149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio232149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017261811", 
          "https://doi.org/10.1038/newbio232149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio232149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017261811", 
          "https://doi.org/10.1038/newbio232149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(72)90107-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017831486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(72)90107-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017831486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1969.tb00769.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019120970"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1071/bi9711199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019574630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.63.4.1181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020046081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1071/bi9720989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020782020"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(71)80556-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021147931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1749-6632.1969.tb20446.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021503662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-5193(73)90252-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021767153"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1070745", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022638683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1070745", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022638683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(71)90105-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023610539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(71)90105-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023610539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0047-2484(72)90009-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024083073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/229391a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024411744", 
          "https://doi.org/10.1038/229391a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/232149a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024947854", 
          "https://doi.org/10.1038/232149a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1968.349.1.433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025274947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1968.349.1.433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025274947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(66)90288-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028705808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1971.tb01708.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029585373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1971.tb01708.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029585373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1971.tb01693.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029749556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1971.tb01693.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029749556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/219131a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029992987", 
          "https://doi.org/10.1038/219131a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(71)90140-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031054991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(71)90140-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031054991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/213269a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032135980", 
          "https://doi.org/10.1038/213269a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-1-4832-2734-4.50017-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032138540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1969.350.1.563", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032385537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(71)90311-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032466008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1970.tb01664.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033327849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4165(65)90350-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034378033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4165(65)90350-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034378033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034409390", 
          "https://doi.org/10.1007/bf00602165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034409390", 
          "https://doi.org/10.1007/bf00602165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034409390", 
          "https://doi.org/10.1007/bf00602165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0047-2484(72)90012-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034577589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01659392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035638159", 
          "https://doi.org/10.1007/bf01659392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01659392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035638159", 
          "https://doi.org/10.1007/bf01659392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(72)90007-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036439545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(72)90007-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036439545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1971.tb01285.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038171097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00487132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038471817", 
          "https://doi.org/10.1007/bf00487132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00487132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038471817", 
          "https://doi.org/10.1007/bf00487132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1972.tb01876.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039321878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/190666a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039647388", 
          "https://doi.org/10.1038/190666a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o70-180", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040324926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-5193(73)90251-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041607308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(67)90606-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041769121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(67)90347-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044650193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00393989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045002056", 
          "https://doi.org/10.1007/bf00393989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00393989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045002056", 
          "https://doi.org/10.1007/bf00393989"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0047-2484(73)90090-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045779642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/220376a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046143989", 
          "https://doi.org/10.1038/220376a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1071/bi9691437", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047868862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1972.tb19717.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051807328"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(67)90591-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051902980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00393988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052718701", 
          "https://doi.org/10.1007/bf00393988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00393988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052718701", 
          "https://doi.org/10.1007/bf00393988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00755a035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055187532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00868a025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055191788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00905a016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.1964.029.01.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060403602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.1966.031.01.090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060403770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.1972.036.01.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060404177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.1972.036.01.046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060404183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.155.3760.279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062490443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.171.3967.182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062502091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.179.4080.1319", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062506801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/1375443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069456708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/2412116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069920601"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3891/acta.chem.scand.25-3532", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071494482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075950776", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076081152", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076243916", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080488691", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080519998", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080708453", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080784368", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080792946", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080820784", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081020643", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081112064", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081247495", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a128183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081392687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081521416", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081523124", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1974-03", 
    "datePublishedReg": "1974-03-01", 
    "description": "Gene phylogenetic trees were constructed by the maximum parsimony method for various sets of ninety six globin chain amino acid sequences spanning plant and animal kingdoms. The method, executed by several computer programs, constructed ancestor and descendant globin messengers on tree topologies which required the least number of nucleotide replacements to account for the evolution of the globins. The human myoglobin-hemoglobin divergence was traced to a gene duplication which occurred either in the first vertebrates or earlier yet in the common ancestor of chordates and annelids, the alpha-beta divergence to a gene duplication in the common ancestor of teleosts and tetrapods, the gamma divergence from typical beta chains to a gene duplication in basal therian mammals, and the delta separation from beta to a duplication in the basal catarrhine primates. Evidence was provided by the globin phylogenies for the hominoid affinities of the gibbon and the close phyletic relationship of the African apes to man. Over the period of teleos-tetrapod divergence the globin messengers evolved at an average rate of 18.5 nucleotide replacements per 100 codons per 108 years, a faster rate than most previous estimates. Very fast and very slow rates were encountered in different globin lineages and at different stages of descent, reducing the effectiveness of globins as molecular clocks. Rates increased with gene duplication and decreased after selection discovered useful specializations in the products of genes which had previously been freer to accept mutations. The early eutherian radiation was characterized by rapid rates of globin evolution, but the later hominoid radiation by extremely slow rates. This pattern was related to more complicated grades of internal organization evolving in human ancestors. The types of nucleotide replacements in the globin messengers over the long course of globin evolution did not seem indicative of any special mutational mechanisms.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf01795974", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1016442", 
        "issn": [
          "0022-2844", 
          "1432-1432"
        ], 
        "name": "Journal of Molecular Evolution", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "3"
      }
    ], 
    "name": "The phylogeny of human globin genes investigated by the maximum parsimony method", 
    "pagination": "1-48", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "9378f7cf22c52732c427affc4a9ab0dac9b4192ef442b3deec788c2339a558be"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "4208305"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0360051"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01795974"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1030956092"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01795974", 
      "https://app.dimensions.ai/details/publication/pub.1030956092"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:33", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113661_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF01795974"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01795974'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01795974'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01795974'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01795974'


 

This table displays all metadata directly associated to this object as RDF triples.

462 TRIPLES      21 PREDICATES      144 URIs      44 LITERALS      32 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01795974 schema:about N0390513228a04af48d66019f5971a122
2 N0b72686704c34a9792e59f88856d2c5d
3 N0b7279c440774c8fa214983f2d6311a2
4 N0e6e784be6af43949262b18fa9f40809
5 N1a46e37f24744488a1825b338626091b
6 N27bd8d0d71ef4f8886fb06f9318a5ea5
7 N380512254ef7448baab28016461774b5
8 N437836b7ddec4003bd7308d87c53798b
9 N5597babd3946497982c446f10886ec22
10 N60fb6490db254eb38c107ef168746098
11 N671a5e752daa41d4b19ccbbdd3ef2607
12 N6f0f8650d2214874a590bbcdb4b6731c
13 N722563e6d557464695fbdaaf130b6f9a
14 N77cd3f03fca243968b12860af7178ff7
15 N8875af4a88db40629ebd7c3c970ae52e
16 Nb1e6dd6571d847a7903c162a80373cb0
17 Nb1ea07036ed24b198122ef6ec8800b6f
18 Nb6a1ae5749444c3bb35192d4ebd06b2e
19 Nc78a905a0fde4fc8bd615ec28fd26455
20 Nd721338337ab43f7992c10ed6725167a
21 Ne0053099a0054fbea088ea8c594c415f
22 Ne708730dc0ab4ead919a231fef7093c4
23 Nedb369c9d9264c188a393934cca9018a
24 anzsrc-for:06
25 anzsrc-for:0604
26 schema:author Nb6f14144548a4f12af3d016fd51c49de
27 schema:citation sg:pub.10.1007/bf00393988
28 sg:pub.10.1007/bf00393989
29 sg:pub.10.1007/bf00487132
30 sg:pub.10.1007/bf00602165
31 sg:pub.10.1007/bf01659392
32 sg:pub.10.1038/190666a0
33 sg:pub.10.1038/192984a0
34 sg:pub.10.1038/205883a0
35 sg:pub.10.1038/213269a0
36 sg:pub.10.1038/219131a0
37 sg:pub.10.1038/2191335a0
38 sg:pub.10.1038/220376a0
39 sg:pub.10.1038/229391a0
40 sg:pub.10.1038/232149a0
41 sg:pub.10.1038/233604a0
42 sg:pub.10.1038/newbio232149a0
43 https://app.dimensions.ai/details/publication/pub.1075950776
44 https://app.dimensions.ai/details/publication/pub.1076081152
45 https://app.dimensions.ai/details/publication/pub.1076243916
46 https://app.dimensions.ai/details/publication/pub.1080488691
47 https://app.dimensions.ai/details/publication/pub.1080519998
48 https://app.dimensions.ai/details/publication/pub.1080708453
49 https://app.dimensions.ai/details/publication/pub.1080784368
50 https://app.dimensions.ai/details/publication/pub.1080792946
51 https://app.dimensions.ai/details/publication/pub.1080820784
52 https://app.dimensions.ai/details/publication/pub.1081020643
53 https://app.dimensions.ai/details/publication/pub.1081112064
54 https://app.dimensions.ai/details/publication/pub.1081247495
55 https://app.dimensions.ai/details/publication/pub.1081521416
56 https://app.dimensions.ai/details/publication/pub.1081523124
57 https://doi.org/10.1002/ajpa.1330240204
58 https://doi.org/10.1016/0003-9861(66)90288-8
59 https://doi.org/10.1016/0003-9861(67)90591-7
60 https://doi.org/10.1016/0003-9861(67)90606-6
61 https://doi.org/10.1016/0005-2795(70)90208-4
62 https://doi.org/10.1016/0005-2795(71)90105-x
63 https://doi.org/10.1016/0005-2795(71)90140-1
64 https://doi.org/10.1016/0005-2795(72)90007-4
65 https://doi.org/10.1016/0005-2795(72)90107-9
66 https://doi.org/10.1016/0006-3002(62)90334-7
67 https://doi.org/10.1016/0014-5793(71)80556-2
68 https://doi.org/10.1016/0022-2836(67)90347-6
69 https://doi.org/10.1016/0022-2836(71)90311-1
70 https://doi.org/10.1016/0022-2836(72)90229-x
71 https://doi.org/10.1016/0022-2836(72)90326-9
72 https://doi.org/10.1016/0022-2836(72)90327-0
73 https://doi.org/10.1016/0022-5193(73)90251-8
74 https://doi.org/10.1016/0022-5193(73)90252-x
75 https://doi.org/10.1016/0047-2484(72)90009-7
76 https://doi.org/10.1016/0047-2484(72)90012-7
77 https://doi.org/10.1016/0047-2484(73)90090-0
78 https://doi.org/10.1016/0304-4165(65)90350-8
79 https://doi.org/10.1016/b978-1-4832-2734-4.50017-6
80 https://doi.org/10.1021/bi00755a035
81 https://doi.org/10.1021/bi00868a025
82 https://doi.org/10.1021/bi00905a016
83 https://doi.org/10.1042/bj1030129
84 https://doi.org/10.1042/bj1070745
85 https://doi.org/10.1071/bi9691437
86 https://doi.org/10.1071/bi9710787
87 https://doi.org/10.1071/bi9711199
88 https://doi.org/10.1071/bi9720989
89 https://doi.org/10.1073/pnas.63.4.1181
90 https://doi.org/10.1093/oxfordjournals.jbchem.a128183
91 https://doi.org/10.1098/rspb.1969.0043
92 https://doi.org/10.1101/sqb.1964.029.01.032
93 https://doi.org/10.1101/sqb.1966.031.01.090
94 https://doi.org/10.1101/sqb.1972.036.01.040
95 https://doi.org/10.1101/sqb.1972.036.01.046
96 https://doi.org/10.1111/j.1399-3011.1970.tb01664.x
97 https://doi.org/10.1111/j.1399-3011.1971.tb01693.x
98 https://doi.org/10.1111/j.1399-3011.1971.tb01708.x
99 https://doi.org/10.1111/j.1399-3011.1972.tb03437.x
100 https://doi.org/10.1111/j.1432-1033.1969.tb00769.x
101 https://doi.org/10.1111/j.1432-1033.1970.tb01103.x
102 https://doi.org/10.1111/j.1432-1033.1971.tb01285.x
103 https://doi.org/10.1111/j.1432-1033.1972.tb01876.x
104 https://doi.org/10.1111/j.1432-1033.1972.tb19717.x
105 https://doi.org/10.1111/j.1749-6632.1969.tb20446.x
106 https://doi.org/10.1126/science.155.3760.279
107 https://doi.org/10.1126/science.171.3967.182
108 https://doi.org/10.1126/science.179.4080.1319
109 https://doi.org/10.1136/bmj.4.5633.748
110 https://doi.org/10.1139/o70-180
111 https://doi.org/10.1515/bchm2.1961.325.1.283
112 https://doi.org/10.1515/bchm2.1966.343.1.290
113 https://doi.org/10.1515/bchm2.1968.349.1.433
114 https://doi.org/10.1515/bchm2.1969.350.1.563
115 https://doi.org/10.2307/1375443
116 https://doi.org/10.2307/2412116
117 https://doi.org/10.3109/10408367009027952
118 https://doi.org/10.3891/acta.chem.scand.25-3532
119 schema:datePublished 1974-03
120 schema:datePublishedReg 1974-03-01
121 schema:description Gene phylogenetic trees were constructed by the maximum parsimony method for various sets of ninety six globin chain amino acid sequences spanning plant and animal kingdoms. The method, executed by several computer programs, constructed ancestor and descendant globin messengers on tree topologies which required the least number of nucleotide replacements to account for the evolution of the globins. The human myoglobin-hemoglobin divergence was traced to a gene duplication which occurred either in the first vertebrates or earlier yet in the common ancestor of chordates and annelids, the alpha-beta divergence to a gene duplication in the common ancestor of teleosts and tetrapods, the gamma divergence from typical beta chains to a gene duplication in basal therian mammals, and the delta separation from beta to a duplication in the basal catarrhine primates. Evidence was provided by the globin phylogenies for the hominoid affinities of the gibbon and the close phyletic relationship of the African apes to man. Over the period of teleos-tetrapod divergence the globin messengers evolved at an average rate of 18.5 nucleotide replacements per 100 codons per 108 years, a faster rate than most previous estimates. Very fast and very slow rates were encountered in different globin lineages and at different stages of descent, reducing the effectiveness of globins as molecular clocks. Rates increased with gene duplication and decreased after selection discovered useful specializations in the products of genes which had previously been freer to accept mutations. The early eutherian radiation was characterized by rapid rates of globin evolution, but the later hominoid radiation by extremely slow rates. This pattern was related to more complicated grades of internal organization evolving in human ancestors. The types of nucleotide replacements in the globin messengers over the long course of globin evolution did not seem indicative of any special mutational mechanisms.
122 schema:genre research_article
123 schema:inLanguage en
124 schema:isAccessibleForFree false
125 schema:isPartOf N3891afdcf6b546989f3592f0cc9c0d42
126 N6adf794c7bdd485dbfb3904fafbac598
127 sg:journal.1016442
128 schema:name The phylogeny of human globin genes investigated by the maximum parsimony method
129 schema:pagination 1-48
130 schema:productId N092632b85c2047feae4ec6054855b485
131 N53b6881b04fc4e489330a34ac551d9be
132 N7e1ad69e91044b2281ec2855d79b41ec
133 Nab249b141b0d462fb15874ae47766c8f
134 Naeeb082637e94f7286fcbd3c169cccef
135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030956092
136 https://doi.org/10.1007/bf01795974
137 schema:sdDatePublished 2019-04-11T10:33
138 schema:sdLicense https://scigraph.springernature.com/explorer/license/
139 schema:sdPublisher Nd5680aeb8e6c42baab1df6262fc4aa89
140 schema:url http://link.springer.com/10.1007/BF01795974
141 sgo:license sg:explorer/license/
142 sgo:sdDataset articles
143 rdf:type schema:ScholarlyArticle
144 N0390513228a04af48d66019f5971a122 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Animals
146 rdf:type schema:DefinedTerm
147 N047f484c24fe4f32991e503f6329a479 rdf:first sg:person.073756526.59
148 rdf:rest rdf:nil
149 N092632b85c2047feae4ec6054855b485 schema:name readcube_id
150 schema:value 9378f7cf22c52732c427affc4a9ab0dac9b4192ef442b3deec788c2339a558be
151 rdf:type schema:PropertyValue
152 N0b72686704c34a9792e59f88856d2c5d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Fishes
154 rdf:type schema:DefinedTerm
155 N0b7279c440774c8fa214983f2d6311a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Amino Acids
157 rdf:type schema:DefinedTerm
158 N0e6e784be6af43949262b18fa9f40809 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Time Factors
160 rdf:type schema:DefinedTerm
161 N1a46e37f24744488a1825b338626091b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Marsupialia
163 rdf:type schema:DefinedTerm
164 N1d78a89c03cc465f808ba84f15f55cab schema:name Department of Biochemistry, Nagasaki University, School of Medicine, Nagasaki, USA
165 rdf:type schema:Organization
166 N27bd8d0d71ef4f8886fb06f9318a5ea5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Myoglobin
168 rdf:type schema:DefinedTerm
169 N380512254ef7448baab28016461774b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Computers
171 rdf:type schema:DefinedTerm
172 N3891afdcf6b546989f3592f0cc9c0d42 schema:issueNumber 1
173 rdf:type schema:PublicationIssue
174 N437836b7ddec4003bd7308d87c53798b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Sharks
176 rdf:type schema:DefinedTerm
177 N53b6881b04fc4e489330a34ac551d9be schema:name pubmed_id
178 schema:value 4208305
179 rdf:type schema:PropertyValue
180 N5597babd3946497982c446f10886ec22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Insecta
182 rdf:type schema:DefinedTerm
183 N5b264f1b3dd84803ace1d1c63e4e33b5 rdf:first sg:person.01032646746.00
184 rdf:rest N7341d9d6944a401bb68efd4f3da45336
185 N60fb6490db254eb38c107ef168746098 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Species Specificity
187 rdf:type schema:DefinedTerm
188 N671a5e752daa41d4b19ccbbdd3ef2607 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Biological Evolution
190 rdf:type schema:DefinedTerm
191 N6adf794c7bdd485dbfb3904fafbac598 schema:volumeNumber 3
192 rdf:type schema:PublicationVolume
193 N6f0f8650d2214874a590bbcdb4b6731c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Genetic Code
195 rdf:type schema:DefinedTerm
196 N722563e6d557464695fbdaaf130b6f9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Genes
198 rdf:type schema:DefinedTerm
199 N7341d9d6944a401bb68efd4f3da45336 rdf:first sg:person.0103050617.29
200 rdf:rest N047f484c24fe4f32991e503f6329a479
201 N77cd3f03fca243968b12860af7178ff7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Haplorhini
203 rdf:type schema:DefinedTerm
204 N7e1ad69e91044b2281ec2855d79b41ec schema:name doi
205 schema:value 10.1007/bf01795974
206 rdf:type schema:PropertyValue
207 N8875af4a88db40629ebd7c3c970ae52e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Humans
209 rdf:type schema:DefinedTerm
210 Nab249b141b0d462fb15874ae47766c8f schema:name dimensions_id
211 schema:value pub.1030956092
212 rdf:type schema:PropertyValue
213 Naeeb082637e94f7286fcbd3c169cccef schema:name nlm_unique_id
214 schema:value 0360051
215 rdf:type schema:PropertyValue
216 Nb1e6dd6571d847a7903c162a80373cb0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
217 schema:name Globins
218 rdf:type schema:DefinedTerm
219 Nb1ea07036ed24b198122ef6ec8800b6f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
220 schema:name Vertebrates
221 rdf:type schema:DefinedTerm
222 Nb6a1ae5749444c3bb35192d4ebd06b2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
223 schema:name Mutation
224 rdf:type schema:DefinedTerm
225 Nb6f14144548a4f12af3d016fd51c49de rdf:first sg:person.01023304676.50
226 rdf:rest N5b264f1b3dd84803ace1d1c63e4e33b5
227 Nc78a905a0fde4fc8bd615ec28fd26455 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
228 schema:name Chickens
229 rdf:type schema:DefinedTerm
230 Nd5680aeb8e6c42baab1df6262fc4aa89 schema:name Springer Nature - SN SciGraph project
231 rdf:type schema:Organization
232 Nd721338337ab43f7992c10ed6725167a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
233 schema:name Amino Acid Sequence
234 rdf:type schema:DefinedTerm
235 Ne0053099a0054fbea088ea8c594c415f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
236 schema:name Cetacea
237 rdf:type schema:DefinedTerm
238 Ne708730dc0ab4ead919a231fef7093c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
239 schema:name Papio
240 rdf:type schema:DefinedTerm
241 Nedb369c9d9264c188a393934cca9018a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
242 schema:name RNA, Messenger
243 rdf:type schema:DefinedTerm
244 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
245 schema:name Biological Sciences
246 rdf:type schema:DefinedTerm
247 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
248 schema:name Genetics
249 rdf:type schema:DefinedTerm
250 sg:journal.1016442 schema:issn 0022-2844
251 1432-1432
252 schema:name Journal of Molecular Evolution
253 rdf:type schema:Periodical
254 sg:person.01023304676.50 schema:affiliation https://www.grid.ac/institutes/grid.254444.7
255 schema:familyName Goodman
256 schema:givenName Morris
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023304676.50
258 rdf:type schema:Person
259 sg:person.0103050617.29 schema:affiliation https://www.grid.ac/institutes/grid.254444.7
260 schema:familyName Barnabas
261 schema:givenName John
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0103050617.29
263 rdf:type schema:Person
264 sg:person.01032646746.00 schema:affiliation https://www.grid.ac/institutes/grid.254444.7
265 schema:familyName Moore
266 schema:givenName G. William
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032646746.00
268 rdf:type schema:Person
269 sg:person.073756526.59 schema:affiliation N1d78a89c03cc465f808ba84f15f55cab
270 schema:familyName Matsuda
271 schema:givenName Genji
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.073756526.59
273 rdf:type schema:Person
274 sg:pub.10.1007/bf00393988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052718701
275 https://doi.org/10.1007/bf00393988
276 rdf:type schema:CreativeWork
277 sg:pub.10.1007/bf00393989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045002056
278 https://doi.org/10.1007/bf00393989
279 rdf:type schema:CreativeWork
280 sg:pub.10.1007/bf00487132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038471817
281 https://doi.org/10.1007/bf00487132
282 rdf:type schema:CreativeWork
283 sg:pub.10.1007/bf00602165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034409390
284 https://doi.org/10.1007/bf00602165
285 rdf:type schema:CreativeWork
286 sg:pub.10.1007/bf01659392 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035638159
287 https://doi.org/10.1007/bf01659392
288 rdf:type schema:CreativeWork
289 sg:pub.10.1038/190666a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039647388
290 https://doi.org/10.1038/190666a0
291 rdf:type schema:CreativeWork
292 sg:pub.10.1038/192984a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013615981
293 https://doi.org/10.1038/192984a0
294 rdf:type schema:CreativeWork
295 sg:pub.10.1038/205883a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009095762
296 https://doi.org/10.1038/205883a0
297 rdf:type schema:CreativeWork
298 sg:pub.10.1038/213269a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032135980
299 https://doi.org/10.1038/213269a0
300 rdf:type schema:CreativeWork
301 sg:pub.10.1038/219131a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029992987
302 https://doi.org/10.1038/219131a0
303 rdf:type schema:CreativeWork
304 sg:pub.10.1038/2191335a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000685490
305 https://doi.org/10.1038/2191335a0
306 rdf:type schema:CreativeWork
307 sg:pub.10.1038/220376a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046143989
308 https://doi.org/10.1038/220376a0
309 rdf:type schema:CreativeWork
310 sg:pub.10.1038/229391a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024411744
311 https://doi.org/10.1038/229391a0
312 rdf:type schema:CreativeWork
313 sg:pub.10.1038/232149a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024947854
314 https://doi.org/10.1038/232149a0
315 rdf:type schema:CreativeWork
316 sg:pub.10.1038/233604a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014394519
317 https://doi.org/10.1038/233604a0
318 rdf:type schema:CreativeWork
319 sg:pub.10.1038/newbio232149a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017261811
320 https://doi.org/10.1038/newbio232149a0
321 rdf:type schema:CreativeWork
322 https://app.dimensions.ai/details/publication/pub.1075950776 schema:CreativeWork
323 https://app.dimensions.ai/details/publication/pub.1076081152 schema:CreativeWork
324 https://app.dimensions.ai/details/publication/pub.1076243916 schema:CreativeWork
325 https://app.dimensions.ai/details/publication/pub.1080488691 schema:CreativeWork
326 https://app.dimensions.ai/details/publication/pub.1080519998 schema:CreativeWork
327 https://app.dimensions.ai/details/publication/pub.1080708453 schema:CreativeWork
328 https://app.dimensions.ai/details/publication/pub.1080784368 schema:CreativeWork
329 https://app.dimensions.ai/details/publication/pub.1080792946 schema:CreativeWork
330 https://app.dimensions.ai/details/publication/pub.1080820784 schema:CreativeWork
331 https://app.dimensions.ai/details/publication/pub.1081020643 schema:CreativeWork
332 https://app.dimensions.ai/details/publication/pub.1081112064 schema:CreativeWork
333 https://app.dimensions.ai/details/publication/pub.1081247495 schema:CreativeWork
334 https://app.dimensions.ai/details/publication/pub.1081521416 schema:CreativeWork
335 https://app.dimensions.ai/details/publication/pub.1081523124 schema:CreativeWork
336 https://doi.org/10.1002/ajpa.1330240204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015798065
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1016/0003-9861(66)90288-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028705808
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1016/0003-9861(67)90591-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051902980
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1016/0003-9861(67)90606-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041769121
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1016/0005-2795(70)90208-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015740311
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1016/0005-2795(71)90105-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023610539
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1016/0005-2795(71)90140-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031054991
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/0005-2795(72)90007-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036439545
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1016/0005-2795(72)90107-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017831486
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1016/0006-3002(62)90334-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014091196
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1016/0014-5793(71)80556-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021147931
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1016/0022-2836(67)90347-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044650193
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1016/0022-2836(71)90311-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032466008
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1016/0022-2836(72)90229-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005925632
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1016/0022-2836(72)90326-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007897490
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1016/0022-2836(72)90327-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005183255
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1016/0022-5193(73)90251-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041607308
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1016/0022-5193(73)90252-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021767153
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1016/0047-2484(72)90009-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024083073
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1016/0047-2484(72)90012-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034577589
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1016/0047-2484(73)90090-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045779642
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1016/0304-4165(65)90350-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034378033
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1016/b978-1-4832-2734-4.50017-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032138540
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1021/bi00755a035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055187532
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1021/bi00868a025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055191788
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1021/bi00905a016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055193154
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1042/bj1030129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010582553
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1042/bj1070745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022638683
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1071/bi9691437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047868862
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1071/bi9710787 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009300091
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1071/bi9711199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019574630
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1071/bi9720989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020782020
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1073/pnas.63.4.1181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020046081
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1093/oxfordjournals.jbchem.a128183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081392687
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1098/rspb.1969.0043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016830093
405 rdf:type schema:CreativeWork
406 https://doi.org/10.1101/sqb.1964.029.01.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060403602
407 rdf:type schema:CreativeWork
408 https://doi.org/10.1101/sqb.1966.031.01.090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060403770
409 rdf:type schema:CreativeWork
410 https://doi.org/10.1101/sqb.1972.036.01.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060404177
411 rdf:type schema:CreativeWork
412 https://doi.org/10.1101/sqb.1972.036.01.046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060404183
413 rdf:type schema:CreativeWork
414 https://doi.org/10.1111/j.1399-3011.1970.tb01664.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033327849
415 rdf:type schema:CreativeWork
416 https://doi.org/10.1111/j.1399-3011.1971.tb01693.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029749556
417 rdf:type schema:CreativeWork
418 https://doi.org/10.1111/j.1399-3011.1971.tb01708.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029585373
419 rdf:type schema:CreativeWork
420 https://doi.org/10.1111/j.1399-3011.1972.tb03437.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013698276
421 rdf:type schema:CreativeWork
422 https://doi.org/10.1111/j.1432-1033.1969.tb00769.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019120970
423 rdf:type schema:CreativeWork
424 https://doi.org/10.1111/j.1432-1033.1970.tb01103.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1012452490
425 rdf:type schema:CreativeWork
426 https://doi.org/10.1111/j.1432-1033.1971.tb01285.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038171097
427 rdf:type schema:CreativeWork
428 https://doi.org/10.1111/j.1432-1033.1972.tb01876.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039321878
429 rdf:type schema:CreativeWork
430 https://doi.org/10.1111/j.1432-1033.1972.tb19717.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051807328
431 rdf:type schema:CreativeWork
432 https://doi.org/10.1111/j.1749-6632.1969.tb20446.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021503662
433 rdf:type schema:CreativeWork
434 https://doi.org/10.1126/science.155.3760.279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062490443
435 rdf:type schema:CreativeWork
436 https://doi.org/10.1126/science.171.3967.182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062502091
437 rdf:type schema:CreativeWork
438 https://doi.org/10.1126/science.179.4080.1319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062506801
439 rdf:type schema:CreativeWork
440 https://doi.org/10.1136/bmj.4.5633.748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016077743
441 rdf:type schema:CreativeWork
442 https://doi.org/10.1139/o70-180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040324926
443 rdf:type schema:CreativeWork
444 https://doi.org/10.1515/bchm2.1961.325.1.283 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005514084
445 rdf:type schema:CreativeWork
446 https://doi.org/10.1515/bchm2.1966.343.1.290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009162334
447 rdf:type schema:CreativeWork
448 https://doi.org/10.1515/bchm2.1968.349.1.433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025274947
449 rdf:type schema:CreativeWork
450 https://doi.org/10.1515/bchm2.1969.350.1.563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032385537
451 rdf:type schema:CreativeWork
452 https://doi.org/10.2307/1375443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069456708
453 rdf:type schema:CreativeWork
454 https://doi.org/10.2307/2412116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069920601
455 rdf:type schema:CreativeWork
456 https://doi.org/10.3109/10408367009027952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003291397
457 rdf:type schema:CreativeWork
458 https://doi.org/10.3891/acta.chem.scand.25-3532 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071494482
459 rdf:type schema:CreativeWork
460 https://www.grid.ac/institutes/grid.254444.7 schema:alternateName Wayne State University
461 schema:name Department of Anatomy, Wayne State University, Medical Research Building 550 E Canfield Avenue, 48201, Detroit, Michigan, USA
462 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...