Effects of aprotinin on hemorrhagic complications in ARDS patients during prolonged extracorporeal CO2 removal View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-06

AUTHORS

F. Brunet, J. P. Mira, M. Belghith, J. J. Lanore, S. Schlumberger, P. Toulon, J. F. Dhainaut

ABSTRACT

The effects of aprotinin, a broad-based proteinase inhibitor, in the management of hemorrhagic complications during prolonged venovenous extracorporeal CO2 removal in patients with adult respiratory distress syndrome are not evaluated. In two patients, aprotinin infusion was added to heparin to treat bleeding, occurring after few days of bypass and responsible for respiratory and hemodynamic deterioration. After aprotinin infusion (loading dose of 2×106 kIU followed by a continuous infusion of 5×105 kIU/h) combined with heparin, bleeding vanished until the end of bypass. More... »

PAGES

364-367

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01694366

DOI

http://dx.doi.org/10.1007/bf01694366

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036329791

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1281849


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197 grid-institutes:grid.414106.6 schema:alternateName Cardiac Surgery Unit, Foch Hospital, Suresnes, France
198 schema:name Cardiac Surgery Unit, Foch Hospital, Suresnes, France
199 rdf:type schema:Organization
 




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