Evolutionary rate of cistrons and DNA divergence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1972-06

AUTHORS

Tomoko Ohta

ABSTRACT

The ratio of DNA divergence to cistron divergence was estimated for various comparisons ofDrosophila and mammalian species. It was shown that a negative correlation exists between this ratio and the length of one generation. It was proposed that the majority of the amino acid substitutions in evolution are the result of random fixation of nearly neutral mutations for which selection intensity fluctuates considerably but the average selection coefficient is very slightly negative. On the other hand, the evolutionary rate of DNA divergence is negatively correlated with the generation time if the majority of mutations are completely neutral and if mutation rate at the nucleotide level is mildly dependent on the generation time. More... »

PAGES

150-157

References to SciGraph publications

Journal

TITLE

Journal of Molecular Evolution

ISSUE

2

VOLUME

1

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01659161

DOI

http://dx.doi.org/10.1007/bf01659161

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024331583

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24173438


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