Do measles early giant cells result from fusion of non-infected cells? An immunohistochemical and in situ hybridization study in a ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-05

AUTHORS

A. Gaulier, P. Sabatier, S. Prevot, J. G. Fournier

ABSTRACT

A case of acute appendicitis with features of measles inflammatory reaction is studied. Two types of lymphoid polykaryons are seen: Warthin Finkeldey cells inside germinal centres (LN1 ++, LN2 +, L26 +, MB1 +, MB2 +/-) and multinucleate plasma cells in the lamina propria (mu +, alpha ++, kappa +, lambda +). Both types of polykaryon are devoid of inclusions. The search for viral genetic information by in situ hybridization was negative in these cells. A positive signal was observed in interfollicular mononuclear cells and rare enterocytes. A possible mechanism of fusion from without, acting at the beginning of the disease to induce the appearance of polykaryons, is discussed. More... »

PAGES

245-249

References to SciGraph publications

  • 1987-03. Analysis of viral antigens in giant cells of measles pneumonia by immunoperoxidase method in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf01626355

    DOI

    http://dx.doi.org/10.1007/bf01626355

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1008330807

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1926766


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