D-19466, a new cyclobutane-platinum complex with antitumor activity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-09

AUTHORS

R. Voegeli, W. Schumacher, J. Engel, J. Respondek, P. Hilgard

ABSTRACT

D-19466, a new platinum complex, was characterized. It showed no nephrotoxic side-effects as determined by the measurement of blood urea. It was cytotoxic in vitro for tumor cells in concentrations comparable to or lower than cytotoxic concentrations of cisplatin. It had excellent anticancer activity in vivo against a number of murine experimental tumors, including a cisplatin-resistant P388 line. Clinical evaluation of this compound has therefore been initiated. More... »

PAGES

439-442

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01612990

DOI

http://dx.doi.org/10.1007/bf01612990

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024067178

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2229133


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