Glomerular tuft ballooning in mitomycin-C-induced renal impairment View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-11

AUTHORS

Hideo Shiiki, Kazuhiro Dohi, Hisayuki Nishioka, Takashi Matsuda, Masao Kanauchi, Hideto Uyama, Hyoe Ishikawa, Teruo Watanabe

ABSTRACT

Severe ballooning of the glomerular tufts was observed in a 65-year-old man who was treated with mitomycin C (MMC) and had typical MMC-induced renal lesions. He developed renal failure and severe anaemia 6 months after initiation of chemotherapy. Ballooned tufts were caused by enormous expansion of the sub-endothelial space simultaneously associated with mesangiolysis. Glomerular cysts, described in a variety of disorders including thrombotic microangiopathy and diabetes mellitus, are derived from cystically dilated and united capillary luminae secondary to mesangiolysis. The morphogenesis of this unusual lesion when induced by MMC differs from that of the glomerular cysts previously reported. More... »

PAGES

545-551

References to SciGraph publications

  • 1982-01. Severe glomerular mesangiolysis in a patient with rectal adenocarcinoma treated with cytotoxic drugs in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf01600261

    DOI

    http://dx.doi.org/10.1007/bf01600261

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1042685131

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1609513


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