Ultrastructural study of biopsy specimens of acute fatty liver of pregnancy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-03

AUTHORS

Morio Takeda, Ichiro Takayama, Yoshinori Miyazaki, Yoshihiro Akahane, Shinichi Ohno, Masayuki A. Fujino

ABSTRACT

Biopsy specimens obtained from the liver of a 32-year-old woman, diagnosed with acute fatty liver of pregnancy, were examined by light and electron microscopy. The patient had become pregnant after artificial insemination. At the 36th week of gestation, she suffered simultaneous fetal distress and liver dysfunction, and a cesarean operation was done immediately. Liver biopsies were performed on the 7th and 38th day after the cesarean operation. The first biopsy revealed enlarged hepatocytes in pericentral areas. Many transformed mitochondria with tubular cristae, which were often seen in steroid hormoneproducing cells and adrenal cortical cells, and microvesicular fatty droplets were detected in some swollen hepatocytes, as revealed by electron microscopy. At the second biopsy, almost all hepatocytes had recovered normal morphology as the result of appropriate treatment. More... »

PAGES

42-48

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01547948

DOI

http://dx.doi.org/10.1007/bf01547948

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049837801


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