A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on chromosome 12 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-07

AUTHORS

Peter W. Andrews, Barbara B. Knowles, Peter N. Goodfellow

ABSTRACT

A murine monoclonal antibody 602-29, subclass IgG1, that recognizes an antigenic determinant expressed by most human cells is described. Immunoprecipitation and sodium dodecyl sulfate-gel electrophoresis analysis indicate that the antigenic determinant is carried by a protein with an apparent molecular weight of 21,000. The antigen is expressed by human-mouse somatic cell hybrids, and analysis of segregants that have lost human chromosomes indicates that the gene controlling expression of the 602-29 antigen is on chromosome 12. More... »

PAGES

435-443

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01542988

DOI

http://dx.doi.org/10.1007/bf01542988

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044843859

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6792721


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