Identification and characterization of a cDNA clone derived from the Marek's disease tumour cell line RPL1 encoding a homologue of ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-02

AUTHORS

D. Koptidesová, J. Kopáček, V. Zelník, N. L. J. Ross, S. Pastoreková, J. Pastorek

ABSTRACT

We have identified and sequenced a 2.3 kb cDNA clone RPL(N.S) 6 derived from the Marek's disease virus (MDV)-transformed cell line RPL1, which contained open reading frames (ORFs) homologous to UL49 (VP22) and UL48 (VP16) of herpes simplex virus. Northern blot hybridization identified a 2.5kb transcript corresponding to this cDNA clone in the total RNA from MSB1 lymphoblastoid cells, but not in RNA from the original RPL1 cells, most probably due to the very low level of its transcription. In vitro translation demonstrated that both MDV UL49 and UL48 can be expressed from a single mRNA. More... »

PAGES

355-362

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01309869

DOI

http://dx.doi.org/10.1007/bf01309869

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031867332

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7710361


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