Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1a, 5-HT1b and 5-HT3 receptors in the ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-10

AUTHORS

A. M. Laporte, C. M. Fattaccini, M. C. Lombard, J. Chauveau, M. Hamon

ABSTRACT

Autoradiographic studies were performed in combination with dorsal rhizotomy or selective lesion of descending serotonergic or noradrenergic systems in an attempt to identify the neuronal cell types endowed with the serotonin 5-HT1a, 5-HT1b and 5-HT3 receptors in the rat spinal cord. Unilateral sectioning of seven dorsal roots (C4–T2) at the cervical level produced a marked decrease (∼−75%, 10 days after the surgery) in the binding of [125I]iodozacopride to 5-HT3 receptors in the superficial layers of the ipsilateral dorsal horn, further confirming the preferential location of these receptors on primary afferent fibres. In addition, a significant decrease (∼20%) in the binding of [3H]8-OH-DPAT to 5-HT1A receptors and of [125I]GTI to 5-HT1B receptors was also observed in the same spinal area in rhizotomized rats, suggesting that a small proportion of these receptors are also located on primary afferent fibres. The labelling of 5-HT1B receptors was significantly decreased (−12%) in the dorsal horn at the cervical (but not the lumbar) level, and that of 5-HT3 receptors was unchanged in the whole spinal cord in rats whose descending serotonergic projections had been destroyed by 5,7-dihydroxytryptamine. Conversely, the labelling of 5-HT1A receptors was significantly increased in the cervical (+13%) and lumbar (+42%) dorsal horn in 5,7-dihydroxytryptamine-lesioned rats. Similarly, [3H]8-OH-DPAT binding to 5-HT1A receptors significantly increased (+26%) in the lumbar (but not the cervical) dorsal horn in rats whose noradrenergic systems had been lesioned by DSP-4. The labelling of 5-HT1B receptors was also increased (+31% at the cervical level; +17% at the lumbar level), whereas that of 5-HT3 receptors remained unchanged in these animals. These data indicate that complex adaptive changes in the expression of 5-HT1A and 5-HT1B receptors occurred in the rat spinal cord following the lesion of descending monoaminergic systems. More... »

PAGES

207-223

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01276459

DOI

http://dx.doi.org/10.1007/bf01276459

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019982666

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8748667


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "5,7-Dihydroxytryptamine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "8-Hydroxy-2-(di-n-propylamino)tetralin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autoradiography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Benzamides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Benzylamines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bridged Bicyclo Compounds, Heterocyclic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dipeptides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Iodine Radioisotopes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nerve Degeneration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons, Afferent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Norepinephrine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Presynaptic Terminals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Sprague-Dawley", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Serotonin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Serotonin, 5-HT1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rhizotomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serotonin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serotonin Antagonists", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serotonin Receptor Agonists", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spinal Cord", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spinal Nerve Roots", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sympathomimetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tritium", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Laporte", 
        "givenName": "A. M.", 
        "id": "sg:person.01117455304.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117455304.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fattaccini", 
        "givenName": "C. M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "INSERM U161, Physiopharmacologie du Syst\u00e8me Nerveux, Paris", 
          "id": "http://www.grid.ac/institutes/grid.7429.8", 
          "name": [
            "INSERM U161, Physiopharmacologie du Syst\u00e8me Nerveux, Paris"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lombard", 
        "givenName": "M. C.", 
        "id": "sg:person.0645357776.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645357776.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "IMMUNOTECH, Marseille, France", 
          "id": "http://www.grid.ac/institutes/grid.424937.f", 
          "name": [
            "IMMUNOTECH, Marseille, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chauveau", 
        "givenName": "J.", 
        "id": "sg:person.01302560526.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302560526.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Facult\u00e9 de M\u00e9decine Piti\u00e9-Salp\u00eatri\u00e8re, INSERM U288, Neurobiologie Cellulaire et Fonctionnell\u00e9, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hamon", 
        "givenName": "M.", 
        "id": "sg:person.0662511653.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662511653.73"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/305140a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011269543", 
          "https://doi.org/10.1038/305140a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-10", 
    "datePublishedReg": "1995-10-01", 
    "description": "Autoradiographic studies were performed in combination with dorsal rhizotomy or selective lesion of descending serotonergic or noradrenergic systems in an attempt to identify the neuronal cell types endowed with the serotonin 5-HT1a, 5-HT1b and 5-HT3 receptors in the rat spinal cord. Unilateral sectioning of seven dorsal roots (C4\u2013T2) at the cervical level produced a marked decrease (\u223c\u221275%, 10 days after the surgery) in the binding of [125I]iodozacopride to 5-HT3 receptors in the superficial layers of the ipsilateral dorsal horn, further confirming the preferential location of these receptors on primary afferent fibres. In addition, a significant decrease (\u223c20%) in the binding of [3H]8-OH-DPAT to 5-HT1A receptors and of [125I]GTI to 5-HT1B receptors was also observed in the same spinal area in rhizotomized rats, suggesting that a small proportion of these receptors are also located on primary afferent fibres. The labelling of 5-HT1B receptors was significantly decreased (\u221212%) in the dorsal horn at the cervical (but not the lumbar) level, and that of 5-HT3 receptors was unchanged in the whole spinal cord in rats whose descending serotonergic projections had been destroyed by 5,7-dihydroxytryptamine. Conversely, the labelling of 5-HT1A receptors was significantly increased in the cervical (+13%) and lumbar (+42%) dorsal horn in 5,7-dihydroxytryptamine-lesioned rats. Similarly, [3H]8-OH-DPAT binding to 5-HT1A receptors significantly increased (+26%) in the lumbar (but not the cervical) dorsal horn in rats whose noradrenergic systems had been lesioned by DSP-4. The labelling of 5-HT1B receptors was also increased (+31% at the cervical level; +17% at the lumbar level), whereas that of 5-HT3 receptors remained unchanged in these animals. These data indicate that complex adaptive changes in the expression of 5-HT1A and 5-HT1B receptors occurred in the rat spinal cord following the lesion of descending monoaminergic systems.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf01276459", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1398620", 
        "name": "Journal of neural transmission", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "100"
      }
    ], 
    "keywords": [
      "rat spinal cord", 
      "lumbar dorsal horn", 
      "primary afferent fibers", 
      "dorsal horn", 
      "spinal cord", 
      "noradrenergic system", 
      "dorsal rhizotomy", 
      "afferent fibers", 
      "cervical level", 
      "selective lesions", 
      "ipsilateral dorsal horn", 
      "whole spinal cord", 
      "neuronal cell types", 
      "dorsal roots", 
      "serotonergic projections", 
      "monoaminergic systems", 
      "DPAT binding", 
      "spinal area", 
      "serotonin 5-HT1A", 
      "complex adaptive changes", 
      "autoradiographic study", 
      "cord", 
      "rats", 
      "lesions", 
      "significant decrease", 
      "receptors", 
      "marked decrease", 
      "rhizotomy", 
      "superficial layers", 
      "adaptive changes", 
      "horn", 
      "cell types", 
      "small proportion", 
      "DSP-4", 
      "DPAT", 
      "labeling", 
      "decrease", 
      "levels", 
      "binding", 
      "animals", 
      "expression", 
      "proportion", 
      "preferential location", 
      "fibers", 
      "study", 
      "effect", 
      "changes", 
      "combination", 
      "addition", 
      "data", 
      "projections", 
      "types", 
      "area", 
      "attempt", 
      "system", 
      "location", 
      "roots", 
      "layer", 
      "same spinal area"
    ], 
    "name": "Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1a, 5-HT1b and 5-HT3 receptors in the rat spinal cord", 
    "pagination": "207-223", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019982666"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01276459"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8748667"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01276459", 
      "https://app.dimensions.ai/details/publication/pub.1019982666"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_288.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf01276459"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01276459'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01276459'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01276459'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01276459'


 

This table displays all metadata directly associated to this object as RDF triples.

260 TRIPLES      22 PREDICATES      113 URIs      104 LITERALS      33 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01276459 schema:about N0dbab6afb5244acbb1b1e1b95d9ed4e4
2 N19b21c7762704ab5854d5b6ec9a184b4
3 N19df587f558b4185ad7b69ce520d647b
4 N30a25fbb43e34382b9590535243a2296
5 N41536e25d9d8452d878a4dfa83fb05ae
6 N6010fcb2bc0d4213ac517dbb31bdc2b4
7 N66aa2795422440e5b22d3b4bd5801089
8 N7acc75752e5c4ad6becea17d58d19cdc
9 N861cc55237a040b99f118a09b621a2a7
10 N872fd96833814aaeade1cb19205f9d3d
11 N8e211592e1bd4f3aad77ecac7a0e6823
12 N956cbbf5a4fe4c2ea1ff4da4dd00efd9
13 N98f200de19e6432dbad55ae24d34f886
14 N9f9976f749ed40d8baeb62606294bdc5
15 Na0cae83cf2954ed5865e7efef2e5d2c3
16 Nb1e31b5dcab94ea39072748bcb66915c
17 Nb36f00058a034a548034bb8530ed3d45
18 Nb4622ce4b331456ab97fa9d043522d9f
19 Nb8e7053891cd44489c81208936803e8a
20 Nc5dba2a8b48c43c286783e8265428725
21 Ndfb644fe941d4a1a89e419cb47b234e5
22 Ne32f692d766d49148ced727521b18ca1
23 Nee0cda350d29405da92014c8b3ee446b
24 Nf18a156bd0894c958d32347052102563
25 Nf6a833e30b1e4143bbff3430071bffdd
26 Nf8add3689c9848489c5cb7bab60880f5
27 anzsrc-for:11
28 anzsrc-for:1109
29 schema:author N8447e19d14b4467a832d2cdf1d345eb0
30 schema:citation sg:pub.10.1038/305140a0
31 schema:datePublished 1995-10
32 schema:datePublishedReg 1995-10-01
33 schema:description Autoradiographic studies were performed in combination with dorsal rhizotomy or selective lesion of descending serotonergic or noradrenergic systems in an attempt to identify the neuronal cell types endowed with the serotonin 5-HT1a, 5-HT1b and 5-HT3 receptors in the rat spinal cord. Unilateral sectioning of seven dorsal roots (C4–T2) at the cervical level produced a marked decrease (∼−75%, 10 days after the surgery) in the binding of [125I]iodozacopride to 5-HT3 receptors in the superficial layers of the ipsilateral dorsal horn, further confirming the preferential location of these receptors on primary afferent fibres. In addition, a significant decrease (∼20%) in the binding of [3H]8-OH-DPAT to 5-HT1A receptors and of [125I]GTI to 5-HT1B receptors was also observed in the same spinal area in rhizotomized rats, suggesting that a small proportion of these receptors are also located on primary afferent fibres. The labelling of 5-HT1B receptors was significantly decreased (−12%) in the dorsal horn at the cervical (but not the lumbar) level, and that of 5-HT3 receptors was unchanged in the whole spinal cord in rats whose descending serotonergic projections had been destroyed by 5,7-dihydroxytryptamine. Conversely, the labelling of 5-HT1A receptors was significantly increased in the cervical (+13%) and lumbar (+42%) dorsal horn in 5,7-dihydroxytryptamine-lesioned rats. Similarly, [3H]8-OH-DPAT binding to 5-HT1A receptors significantly increased (+26%) in the lumbar (but not the cervical) dorsal horn in rats whose noradrenergic systems had been lesioned by DSP-4. The labelling of 5-HT1B receptors was also increased (+31% at the cervical level; +17% at the lumbar level), whereas that of 5-HT3 receptors remained unchanged in these animals. These data indicate that complex adaptive changes in the expression of 5-HT1A and 5-HT1B receptors occurred in the rat spinal cord following the lesion of descending monoaminergic systems.
34 schema:genre article
35 schema:inLanguage en
36 schema:isAccessibleForFree false
37 schema:isPartOf N8304bb12bad3401ca6602a2a5e129a4a
38 Nfd94fd1db98b461e889eaf910701123c
39 sg:journal.1398620
40 schema:keywords DPAT
41 DPAT binding
42 DSP-4
43 adaptive changes
44 addition
45 afferent fibers
46 animals
47 area
48 attempt
49 autoradiographic study
50 binding
51 cell types
52 cervical level
53 changes
54 combination
55 complex adaptive changes
56 cord
57 data
58 decrease
59 dorsal horn
60 dorsal rhizotomy
61 dorsal roots
62 effect
63 expression
64 fibers
65 horn
66 ipsilateral dorsal horn
67 labeling
68 layer
69 lesions
70 levels
71 location
72 lumbar dorsal horn
73 marked decrease
74 monoaminergic systems
75 neuronal cell types
76 noradrenergic system
77 preferential location
78 primary afferent fibers
79 projections
80 proportion
81 rat spinal cord
82 rats
83 receptors
84 rhizotomy
85 roots
86 same spinal area
87 selective lesions
88 serotonergic projections
89 serotonin 5-HT1A
90 significant decrease
91 small proportion
92 spinal area
93 spinal cord
94 study
95 superficial layers
96 system
97 types
98 whole spinal cord
99 schema:name Effects of dorsal rhizotomy and selective lesion of serotonergic and noradrenergic systems on 5-HT1a, 5-HT1b and 5-HT3 receptors in the rat spinal cord
100 schema:pagination 207-223
101 schema:productId N0abeb003661a427aa9fe184ee2e72b4e
102 Nb48fc69d611d47428760764448f32044
103 Ne8fbef3c7b834334a90cbddc68234d98
104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019982666
105 https://doi.org/10.1007/bf01276459
106 schema:sdDatePublished 2021-12-01T19:10
107 schema:sdLicense https://scigraph.springernature.com/explorer/license/
108 schema:sdPublisher N7dfc832f56c943839d09ad86b5ad19ee
109 schema:url https://doi.org/10.1007/bf01276459
110 sgo:license sg:explorer/license/
111 sgo:sdDataset articles
112 rdf:type schema:ScholarlyArticle
113 N0abeb003661a427aa9fe184ee2e72b4e schema:name doi
114 schema:value 10.1007/bf01276459
115 rdf:type schema:PropertyValue
116 N0ac3aa158ee54fe790329e19eca0e534 rdf:first sg:person.0645357776.47
117 rdf:rest Nf182121640c84800af8a03f543091dd6
118 N0dbab6afb5244acbb1b1e1b95d9ed4e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Sympathomimetics
120 rdf:type schema:DefinedTerm
121 N19b21c7762704ab5854d5b6ec9a184b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Serotonin Antagonists
123 rdf:type schema:DefinedTerm
124 N19df587f558b4185ad7b69ce520d647b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Animals
126 rdf:type schema:DefinedTerm
127 N30a25fbb43e34382b9590535243a2296 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Neurons, Afferent
129 rdf:type schema:DefinedTerm
130 N38fb4df0c03240adb2ac9adb1d78509c schema:affiliation grid-institutes:None
131 schema:familyName Fattaccini
132 schema:givenName C. M.
133 rdf:type schema:Person
134 N41536e25d9d8452d878a4dfa83fb05ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Nerve Degeneration
136 rdf:type schema:DefinedTerm
137 N44d5092effe140baa2cb1a7dc613883f rdf:first sg:person.0662511653.73
138 rdf:rest rdf:nil
139 N4c74c4a05da74e17af84684ad65b8ca3 rdf:first N38fb4df0c03240adb2ac9adb1d78509c
140 rdf:rest N0ac3aa158ee54fe790329e19eca0e534
141 N6010fcb2bc0d4213ac517dbb31bdc2b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Bridged Bicyclo Compounds, Heterocyclic
143 rdf:type schema:DefinedTerm
144 N66aa2795422440e5b22d3b4bd5801089 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Rats, Sprague-Dawley
146 rdf:type schema:DefinedTerm
147 N7acc75752e5c4ad6becea17d58d19cdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Rats
149 rdf:type schema:DefinedTerm
150 N7dfc832f56c943839d09ad86b5ad19ee schema:name Springer Nature - SN SciGraph project
151 rdf:type schema:Organization
152 N8304bb12bad3401ca6602a2a5e129a4a schema:volumeNumber 100
153 rdf:type schema:PublicationVolume
154 N8447e19d14b4467a832d2cdf1d345eb0 rdf:first sg:person.01117455304.89
155 rdf:rest N4c74c4a05da74e17af84684ad65b8ca3
156 N861cc55237a040b99f118a09b621a2a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Autoradiography
158 rdf:type schema:DefinedTerm
159 N872fd96833814aaeade1cb19205f9d3d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Benzylamines
161 rdf:type schema:DefinedTerm
162 N8e211592e1bd4f3aad77ecac7a0e6823 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Spinal Cord
164 rdf:type schema:DefinedTerm
165 N956cbbf5a4fe4c2ea1ff4da4dd00efd9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Norepinephrine
167 rdf:type schema:DefinedTerm
168 N98f200de19e6432dbad55ae24d34f886 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Receptors, Serotonin
170 rdf:type schema:DefinedTerm
171 N9f9976f749ed40d8baeb62606294bdc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name 5,7-Dihydroxytryptamine
173 rdf:type schema:DefinedTerm
174 Na0cae83cf2954ed5865e7efef2e5d2c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Benzamides
176 rdf:type schema:DefinedTerm
177 Nb1e31b5dcab94ea39072748bcb66915c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Male
179 rdf:type schema:DefinedTerm
180 Nb36f00058a034a548034bb8530ed3d45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Iodine Radioisotopes
182 rdf:type schema:DefinedTerm
183 Nb4622ce4b331456ab97fa9d043522d9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Presynaptic Terminals
185 rdf:type schema:DefinedTerm
186 Nb48fc69d611d47428760764448f32044 schema:name pubmed_id
187 schema:value 8748667
188 rdf:type schema:PropertyValue
189 Nb8e7053891cd44489c81208936803e8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Spinal Nerve Roots
191 rdf:type schema:DefinedTerm
192 Nc5dba2a8b48c43c286783e8265428725 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Rhizotomy
194 rdf:type schema:DefinedTerm
195 Ndfb644fe941d4a1a89e419cb47b234e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Serotonin Receptor Agonists
197 rdf:type schema:DefinedTerm
198 Ne32f692d766d49148ced727521b18ca1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name 8-Hydroxy-2-(di-n-propylamino)tetralin
200 rdf:type schema:DefinedTerm
201 Ne8fbef3c7b834334a90cbddc68234d98 schema:name dimensions_id
202 schema:value pub.1019982666
203 rdf:type schema:PropertyValue
204 Nee0cda350d29405da92014c8b3ee446b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Dipeptides
206 rdf:type schema:DefinedTerm
207 Nf182121640c84800af8a03f543091dd6 rdf:first sg:person.01302560526.00
208 rdf:rest N44d5092effe140baa2cb1a7dc613883f
209 Nf18a156bd0894c958d32347052102563 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
210 schema:name Serotonin
211 rdf:type schema:DefinedTerm
212 Nf6a833e30b1e4143bbff3430071bffdd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
213 schema:name Receptors, Serotonin, 5-HT1
214 rdf:type schema:DefinedTerm
215 Nf8add3689c9848489c5cb7bab60880f5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
216 schema:name Tritium
217 rdf:type schema:DefinedTerm
218 Nfd94fd1db98b461e889eaf910701123c schema:issueNumber 3
219 rdf:type schema:PublicationIssue
220 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
221 schema:name Medical and Health Sciences
222 rdf:type schema:DefinedTerm
223 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
224 schema:name Neurosciences
225 rdf:type schema:DefinedTerm
226 sg:journal.1398620 schema:name Journal of neural transmission
227 schema:publisher Springer Nature
228 rdf:type schema:Periodical
229 sg:person.01117455304.89 schema:affiliation grid-institutes:None
230 schema:familyName Laporte
231 schema:givenName A. M.
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117455304.89
233 rdf:type schema:Person
234 sg:person.01302560526.00 schema:affiliation grid-institutes:grid.424937.f
235 schema:familyName Chauveau
236 schema:givenName J.
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302560526.00
238 rdf:type schema:Person
239 sg:person.0645357776.47 schema:affiliation grid-institutes:grid.7429.8
240 schema:familyName Lombard
241 schema:givenName M. C.
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645357776.47
243 rdf:type schema:Person
244 sg:person.0662511653.73 schema:affiliation grid-institutes:None
245 schema:familyName Hamon
246 schema:givenName M.
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662511653.73
248 rdf:type schema:Person
249 sg:pub.10.1038/305140a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011269543
250 https://doi.org/10.1038/305140a0
251 rdf:type schema:CreativeWork
252 grid-institutes:None schema:alternateName Faculté de Médecine Pitié-Salpêtrière, INSERM U288, Neurobiologie Cellulaire et Fonctionnellé, France
253 schema:name Faculté de Médecine Pitié-Salpêtrière, INSERM U288, Neurobiologie Cellulaire et Fonctionnellé, France
254 rdf:type schema:Organization
255 grid-institutes:grid.424937.f schema:alternateName IMMUNOTECH, Marseille, France
256 schema:name IMMUNOTECH, Marseille, France
257 rdf:type schema:Organization
258 grid-institutes:grid.7429.8 schema:alternateName INSERM U161, Physiopharmacologie du Système Nerveux, Paris
259 schema:name INSERM U161, Physiopharmacologie du Système Nerveux, Paris
260 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...