The impact of intraoperative brachytherapy on surgery of Ewing's sarcoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-01

AUTHORS

Toshifumi Ozaki, Axel Hillmann, Christian Rübe, Robert Rödl, Martin Hein, Christiane Hoffmann, Sebastian Blasius, Herbert Jürgens, Winfried Winkelmann

ABSTRACT

Surgery of Ewing's sarcoma sometimes results in an inadequate surgical margin. The influence of intra-operative brachytherapy on local control of the tumor, operation time, blood loss, and surgical complications was evaluated, comparing the results of 20 patients who received brachytherapy to a series of 42 patients receiving surgery without brachytherapy. The dose of intraoperative brachytherapy ranged between 9 Gy and 21 Gy. The average operation time was longer in 20 cases with brachytherapy (7.9 h) than in 42 cases without brachytherapy (4.3 h) (P<0.0001). The average blood loss in the groups with (3531 ml) and without brachytherapy (3515 ml) was comparable (P=0.3840). The surgical complication rate in patients receiving brachytherapy was also similar to that of untreated patients (30% versus 31%,P=0.7690). Local relapse developed in 1 of 20 patients who received brachytherapy and 1 of 42 patients without brachytherapy. On the basis of this analysis, it can be concluded that this procedure is safe and does not increase of the acute complication rate. The latest results of local controls are awaited. More... »

PAGES

53-56

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01212615

DOI

http://dx.doi.org/10.1007/bf01212615

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012007971

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8996541


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