Ontology type: schema:ScholarlyArticle
1995-08
AUTHORSN. V. Makarova, Zh. V. Koronova, A. V. Plotnietse, D. Ya. Tirzite, G. D. Tirzit, G. Ya. Duburs
ABSTRACTThere has been synthesized a series of 1,4-dihydropyridines having an N-alkylpyridinium substituent at position 4 with a varying length of hydrocarbon chain. Their affinity to model (liposomal) membranes has been studied. It was found that this affinity increased with lengthening of the hydrocarbon chain on the Npyridinium substituent at the 4-position of the 1,4-dihydropyridine ring. However, lengthening of the hydrocarbon chain in the 3,5-ester groups of the 1, 4-dihydropyridine ring led to a decrease in the binding to the liposome when a 4-(N-hexadecylpyridinium) substituent was present. More... »
PAGES969-973
http://scigraph.springernature.com/pub.10.1007/bf01170324
DOIhttp://dx.doi.org/10.1007/bf01170324
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