Activation of protein kinase C modulates the expression of the T3/T cell antigen receptor complex on human T lymphocytes View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1985-10

AUTHORS

Adelina A. Davies, Doreen A. Cantrell, Michael J. Crumpton

ABSTRACT

Activators of protein kinase C induced a rapid decrease (within 15 min) in the surface expression of the T3 antigen and T-lymphocyte antigen receptor (Ti) on HPB-ALL cells, and a concomitant phosphorylation of the T3 gamma and delta polypeptides; the gamma chain was more extensively phosphorylated than the delta chain. No phosphorylation of the T3 epsilon chain and the Ti alpha and beta polypeptides was detected. Evidence was obtained that the T3 gamma chain is phosphorylated only on serine residues. More... »

PAGES

867-876

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01119898

DOI

http://dx.doi.org/10.1007/bf01119898

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000431160

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3879456


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