Assembly of DNA onto the histone octamer facilitates the B-to-Z transition View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-05

AUTHORS

F. D. Miller, J. B. Rattner, J. H. van de Sande

ABSTRACT

Nucleosomal core particles containing the right- and left-handed conformations of DNA were examined for their ability to support the B→Z or Z→B transition. Nucleosomes were assembled onto the B- and Z-conformations of poly[d(Gm5C)] and the B-conformation of poly[d(GC)] as previously described (1). Absorbance and circular dichroic spectroscopy indicated that the DNA on all three core particle populations could undergo the conformational B↔Z transition. Further, the right- to left-handed transition for both poly[d(Gm5C)] and poly[d(GC)] appeared to be facilitated by the DNAs association with the histone octamer. The DNA remained associated with the protein core subsequent to the transition, and electron microscopy and sedimentation velocity analysis indicated that there were no gross changes in nucleosomal structure. However, a change in the sedimentation value of the poly[d(Gm5C)] core particles was detected when the conformation of the DNA was altered from B to Z, resulting in a lower S20,w value for the Z-form particles than for the corresponding B-form particles. More... »

PAGES

467-476

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01116138

DOI

http://dx.doi.org/10.1007/bf01116138

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021240144

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3742017


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Vitro Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nucleic Acid Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nucleosomes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada", 
          "id": "http://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miller", 
        "givenName": "F. D.", 
        "id": "sg:person.011535750057.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011535750057.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Anatomy, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada", 
          "id": "http://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Anatomy, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rattner", 
        "givenName": "J. B.", 
        "id": "sg:person.01145732353.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145732353.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada", 
          "id": "http://www.grid.ac/institutes/grid.22072.35", 
          "name": [
            "Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "van de Sande", 
        "givenName": "J. H.", 
        "id": "sg:person.01174707310.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174707310.48"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/303674a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016233017", 
          "https://doi.org/10.1038/303674a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1986-05", 
    "datePublishedReg": "1986-05-01", 
    "description": "Nucleosomal core particles containing the right- and left-handed conformations of DNA were examined for their ability to support the B\u2192Z or Z\u2192B transition. Nucleosomes were assembled onto the B- and Z-conformations of poly[d(Gm5C)] and the B-conformation of poly[d(GC)] as previously described (1). Absorbance and circular dichroic spectroscopy indicated that the DNA on all three core particle populations could undergo the conformational B\u2194Z transition. Further, the right- to left-handed transition for both poly[d(Gm5C)] and poly[d(GC)] appeared to be facilitated by the DNAs association with the histone octamer. The DNA remained associated with the protein core subsequent to the transition, and electron microscopy and sedimentation velocity analysis indicated that there were no gross changes in nucleosomal structure. However, a change in the sedimentation value of the poly[d(Gm5C)] core particles was detected when the conformation of the DNA was altered from B to Z, resulting in a lower S20,w value for the Z-form particles than for the corresponding B-form particles.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf01116138", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1092277", 
        "issn": [
          "0144-8463", 
          "1573-4935"
        ], 
        "name": "Bioscience Reports", 
        "publisher": "Portland Press", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "6"
      }
    ], 
    "keywords": [
      "circular dichroic spectroscopy", 
      "left-handed conformations", 
      "assembly of DNA", 
      "core particles", 
      "B conformation", 
      "Z conformation", 
      "Z transition", 
      "electron microscopy", 
      "sedimentation velocity analysis", 
      "conformation", 
      "particles", 
      "octamer", 
      "spectroscopy", 
      "protein core", 
      "absorbance", 
      "nucleosomal core particles", 
      "histone octamer", 
      "microscopy", 
      "transition", 
      "assembly", 
      "structure", 
      "DNA", 
      "particle populations", 
      "core", 
      "values", 
      "gross changes", 
      "ability", 
      "changes", 
      "analysis", 
      "nucleosomal structure", 
      "sedimentation value", 
      "velocity analysis", 
      "nucleosomes", 
      "association", 
      "population", 
      "rights"
    ], 
    "name": "Assembly of DNA onto the histone octamer facilitates the B-to-Z transition", 
    "pagination": "467-476", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1021240144"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01116138"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "3742017"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01116138", 
      "https://app.dimensions.ai/details/publication/pub.1021240144"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_203.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf01116138"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01116138'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01116138'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01116138'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01116138'


 

This table displays all metadata directly associated to this object as RDF triples.

141 TRIPLES      21 PREDICATES      69 URIs      60 LITERALS      13 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01116138 schema:about N3eff4e669de44e55886f936d30c82c0f
2 N5df4dcf7bfc74022ba2876b515039735
3 N7ab3fd5fa857401ab24d620016cb5f35
4 Nc0f0d9618bda48a7b2f16978d7b7e9f6
5 Nee11f688793d4473961f3ffd1f79660a
6 Nfbcd78c87b104bc6a8aab57fd59b3d2a
7 anzsrc-for:06
8 anzsrc-for:0601
9 schema:author Nab51c789419c437eaa93d8d61be1fea0
10 schema:citation sg:pub.10.1038/303674a0
11 schema:datePublished 1986-05
12 schema:datePublishedReg 1986-05-01
13 schema:description Nucleosomal core particles containing the right- and left-handed conformations of DNA were examined for their ability to support the B→Z or Z→B transition. Nucleosomes were assembled onto the B- and Z-conformations of poly[d(Gm5C)] and the B-conformation of poly[d(GC)] as previously described (1). Absorbance and circular dichroic spectroscopy indicated that the DNA on all three core particle populations could undergo the conformational B↔Z transition. Further, the right- to left-handed transition for both poly[d(Gm5C)] and poly[d(GC)] appeared to be facilitated by the DNAs association with the histone octamer. The DNA remained associated with the protein core subsequent to the transition, and electron microscopy and sedimentation velocity analysis indicated that there were no gross changes in nucleosomal structure. However, a change in the sedimentation value of the poly[d(Gm5C)] core particles was detected when the conformation of the DNA was altered from B to Z, resulting in a lower S20,w value for the Z-form particles than for the corresponding B-form particles.
14 schema:genre article
15 schema:isAccessibleForFree false
16 schema:isPartOf N52aaa61f387a409f9eb82ffa5de10ae8
17 Nf6e4caa17d5749e0a8227ac5af5116f4
18 sg:journal.1092277
19 schema:keywords B conformation
20 DNA
21 Z conformation
22 Z transition
23 ability
24 absorbance
25 analysis
26 assembly
27 assembly of DNA
28 association
29 changes
30 circular dichroic spectroscopy
31 conformation
32 core
33 core particles
34 electron microscopy
35 gross changes
36 histone octamer
37 left-handed conformations
38 microscopy
39 nucleosomal core particles
40 nucleosomal structure
41 nucleosomes
42 octamer
43 particle populations
44 particles
45 population
46 protein core
47 rights
48 sedimentation value
49 sedimentation velocity analysis
50 spectroscopy
51 structure
52 transition
53 values
54 velocity analysis
55 schema:name Assembly of DNA onto the histone octamer facilitates the B-to-Z transition
56 schema:pagination 467-476
57 schema:productId N2492439b9d9e430b939709d8df85bdc9
58 N4ea4b50b44574d90a0c7854168b8e5bc
59 N5a9b509ef7e0463d834ec02606c8f05d
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021240144
61 https://doi.org/10.1007/bf01116138
62 schema:sdDatePublished 2022-12-01T06:19
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher Ne3e5d6e037ce42219c97b6432575f2bd
65 schema:url https://doi.org/10.1007/bf01116138
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N0bee218ddeb74501affa01e1194251f9 rdf:first sg:person.01145732353.17
70 rdf:rest N7e8d9b61e9e2486bad715dfad084b947
71 N2492439b9d9e430b939709d8df85bdc9 schema:name doi
72 schema:value 10.1007/bf01116138
73 rdf:type schema:PropertyValue
74 N3eff4e669de44e55886f936d30c82c0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Nucleic Acid Conformation
76 rdf:type schema:DefinedTerm
77 N4ea4b50b44574d90a0c7854168b8e5bc schema:name dimensions_id
78 schema:value pub.1021240144
79 rdf:type schema:PropertyValue
80 N52aaa61f387a409f9eb82ffa5de10ae8 schema:volumeNumber 6
81 rdf:type schema:PublicationVolume
82 N5a9b509ef7e0463d834ec02606c8f05d schema:name pubmed_id
83 schema:value 3742017
84 rdf:type schema:PropertyValue
85 N5df4dcf7bfc74022ba2876b515039735 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Protein Conformation
87 rdf:type schema:DefinedTerm
88 N7ab3fd5fa857401ab24d620016cb5f35 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name In Vitro Techniques
90 rdf:type schema:DefinedTerm
91 N7e8d9b61e9e2486bad715dfad084b947 rdf:first sg:person.01174707310.48
92 rdf:rest rdf:nil
93 Nab51c789419c437eaa93d8d61be1fea0 rdf:first sg:person.011535750057.00
94 rdf:rest N0bee218ddeb74501affa01e1194251f9
95 Nc0f0d9618bda48a7b2f16978d7b7e9f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name DNA
97 rdf:type schema:DefinedTerm
98 Ne3e5d6e037ce42219c97b6432575f2bd schema:name Springer Nature - SN SciGraph project
99 rdf:type schema:Organization
100 Nee11f688793d4473961f3ffd1f79660a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Histones
102 rdf:type schema:DefinedTerm
103 Nf6e4caa17d5749e0a8227ac5af5116f4 schema:issueNumber 5
104 rdf:type schema:PublicationIssue
105 Nfbcd78c87b104bc6a8aab57fd59b3d2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Nucleosomes
107 rdf:type schema:DefinedTerm
108 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
109 schema:name Biological Sciences
110 rdf:type schema:DefinedTerm
111 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
112 schema:name Biochemistry and Cell Biology
113 rdf:type schema:DefinedTerm
114 sg:journal.1092277 schema:issn 0144-8463
115 1573-4935
116 schema:name Bioscience Reports
117 schema:publisher Portland Press
118 rdf:type schema:Periodical
119 sg:person.01145732353.17 schema:affiliation grid-institutes:grid.22072.35
120 schema:familyName Rattner
121 schema:givenName J. B.
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145732353.17
123 rdf:type schema:Person
124 sg:person.011535750057.00 schema:affiliation grid-institutes:grid.22072.35
125 schema:familyName Miller
126 schema:givenName F. D.
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011535750057.00
128 rdf:type schema:Person
129 sg:person.01174707310.48 schema:affiliation grid-institutes:grid.22072.35
130 schema:familyName van de Sande
131 schema:givenName J. H.
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174707310.48
133 rdf:type schema:Person
134 sg:pub.10.1038/303674a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016233017
135 https://doi.org/10.1038/303674a0
136 rdf:type schema:CreativeWork
137 grid-institutes:grid.22072.35 schema:alternateName Department of Anatomy, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada
138 Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada
139 schema:name Department of Anatomy, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada
140 Department of Medical Biochemistry, The University of Calgary, T2N 4N1, Calgary, Alberta, Canada
141 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...