Radiation-induced malignant fibrous histiocytoma of the brachial plexus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-10

AUTHORS

Kenneth C. Gorson, Scherazad Musaphir, Ellen S. Lathi, Gail Wolfe

ABSTRACT

Brachial plexopathy is a common and disabling complication in cancer patients most often attributed to metastasis or radiation-induced fibrosis. Occasionally, other rare but potentially treatable causes are found. A 73 year old woman had a left radical mastectomy followed by radiation to the chest wall and axilla 24 years ago. She recently presented with left arm pain, chronic, nonprogressive lymphedema, profound distal arm sensory loss and progressive severe hand weakness. There was moderate atrophy of all intrinsic hand muscles, anesthesia of the hypothenar eminence and 4th and 5th digits, and no adenopathy or palpable mass in the axilla. EMG confirmed a brachial plexopathy. MRI showed loss of tissue planes consistent with radiation fibrosis, but CT showed a discrete mass in the brachial plexus. Open biopsy showed pleomorphic spindle shaped cells with immunoperoxidase stains consistent with malignant fibrous histiocytoma. Radiation-induced malignant fibrous histiocytoma may present with a brachial plexopathy in the absence of a palpable mass and should be considered in the differential diagnosis of brachial plexus lesions in cancer patients. CT scanning through the plexus may be useful when MRI is normal or equivocal. More... »

PAGES

73-77

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01054771

DOI

http://dx.doi.org/10.1007/bf01054771

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035557755

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8583247


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