Effect of phosphorylation of latrotoxin-like brain protein on its fusogenic properties View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-01

AUTHORS

L. I. Kolchinskaya, T. F. Kastrykina, I. O. Trikash, Ya. T. Terletskaya, M. K. Malysheva

ABSTRACT

A latrotoxin-like protein isolated from the bovine brain is shown to be a cAMP-dependent protein kinase substrate. The fusogenic activity of the protein was determined from the extent of mixing of content of the negatively charged liposomes in the presence of native or phosphorylated protein preparations. It was shown that phosphorylation of the protein considerably decreased its fusogenic activity at pH 7.5, but increased this activity at pH 6.0. The possible regulatory role of the phosphorylation in the functioning of latrotoxin-like protein is suggested. More... »

PAGES

58-61

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01054569

DOI

http://dx.doi.org/10.1007/bf01054569

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053278847


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1116", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Physiology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.418751.e", 
          "name": [
            "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kolchinskaya", 
        "givenName": "L. I.", 
        "id": "sg:person.01064235363.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064235363.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.418751.e", 
          "name": [
            "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kastrykina", 
        "givenName": "T. F.", 
        "id": "sg:person.011462776151.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011462776151.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.419966.5", 
          "name": [
            "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Trikash", 
        "givenName": "I. O.", 
        "id": "sg:person.060040255.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.060040255.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.419966.5", 
          "name": [
            "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Terletskaya", 
        "givenName": "Ya. T.", 
        "id": "sg:person.015323536244.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015323536244.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine", 
          "id": "http://www.grid.ac/institutes/grid.418751.e", 
          "name": [
            "Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Malysheva", 
        "givenName": "M. K.", 
        "id": "sg:person.01233405241.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233405241.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01054256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044736490", 
          "https://doi.org/10.1007/bf01054256"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-01", 
    "datePublishedReg": "1995-01-01", 
    "description": "A latrotoxin-like protein isolated from the bovine brain is shown to be a cAMP-dependent protein kinase substrate. The fusogenic activity of the protein was determined from the extent of mixing of content of the negatively charged liposomes in the presence of native or phosphorylated protein preparations. It was shown that phosphorylation of the protein considerably decreased its fusogenic activity at pH 7.5, but increased this activity at pH 6.0. The possible regulatory role of the phosphorylation in the functioning of latrotoxin-like protein is suggested.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf01054569", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1016854", 
        "issn": [
          "0090-2977", 
          "1573-9007"
        ], 
        "name": "Neurophysiology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "keywords": [
      "cAMP-dependent protein kinase substrates", 
      "protein kinase substrates", 
      "fusogenic activity", 
      "effect of phosphorylation", 
      "kinase substrate", 
      "possible regulatory role", 
      "regulatory role", 
      "latrotoxin-like protein", 
      "protein preparations", 
      "phosphorylation", 
      "protein", 
      "bovine brain", 
      "fusogenic properties", 
      "brain proteins", 
      "activity", 
      "substrate", 
      "role", 
      "liposomes", 
      "presence", 
      "brain", 
      "functioning", 
      "content", 
      "extent", 
      "effect", 
      "preparation", 
      "properties", 
      "phosphorylated protein preparations", 
      "latrotoxin-like brain protein"
    ], 
    "name": "Effect of phosphorylation of latrotoxin-like brain protein on its fusogenic properties", 
    "pagination": "58-61", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053278847"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01054569"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01054569", 
      "https://app.dimensions.ai/details/publication/pub.1053278847"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:10", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_290.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf01054569"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01054569'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01054569'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01054569'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01054569'


 

This table displays all metadata directly associated to this object as RDF triples.

125 TRIPLES      22 PREDICATES      56 URIs      46 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01054569 schema:about anzsrc-for:11
2 anzsrc-for:1109
3 anzsrc-for:1116
4 schema:author N3c89e833939e48e99f7545864be9b176
5 schema:citation sg:pub.10.1007/bf01054256
6 schema:datePublished 1995-01
7 schema:datePublishedReg 1995-01-01
8 schema:description A latrotoxin-like protein isolated from the bovine brain is shown to be a cAMP-dependent protein kinase substrate. The fusogenic activity of the protein was determined from the extent of mixing of content of the negatively charged liposomes in the presence of native or phosphorylated protein preparations. It was shown that phosphorylation of the protein considerably decreased its fusogenic activity at pH 7.5, but increased this activity at pH 6.0. The possible regulatory role of the phosphorylation in the functioning of latrotoxin-like protein is suggested.
9 schema:genre article
10 schema:inLanguage en
11 schema:isAccessibleForFree false
12 schema:isPartOf N7d0a396e63954b91a05408a09c7a72ee
13 Nf30aa21d89f3459496e42faeb761536e
14 sg:journal.1016854
15 schema:keywords activity
16 bovine brain
17 brain
18 brain proteins
19 cAMP-dependent protein kinase substrates
20 content
21 effect
22 effect of phosphorylation
23 extent
24 functioning
25 fusogenic activity
26 fusogenic properties
27 kinase substrate
28 latrotoxin-like brain protein
29 latrotoxin-like protein
30 liposomes
31 phosphorylated protein preparations
32 phosphorylation
33 possible regulatory role
34 preparation
35 presence
36 properties
37 protein
38 protein kinase substrates
39 protein preparations
40 regulatory role
41 role
42 substrate
43 schema:name Effect of phosphorylation of latrotoxin-like brain protein on its fusogenic properties
44 schema:pagination 58-61
45 schema:productId Nb5f76b6732924ba59d19d333c77be7a2
46 Nc24d86e8edd24e4c98c56e54cb96f6fa
47 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053278847
48 https://doi.org/10.1007/bf01054569
49 schema:sdDatePublished 2021-12-01T19:10
50 schema:sdLicense https://scigraph.springernature.com/explorer/license/
51 schema:sdPublisher N682aa67165324becadac021bc775707b
52 schema:url https://doi.org/10.1007/bf01054569
53 sgo:license sg:explorer/license/
54 sgo:sdDataset articles
55 rdf:type schema:ScholarlyArticle
56 N0f5b75d970c84796971d216968d7db83 rdf:first sg:person.015323536244.18
57 rdf:rest N5c8463c4458f44e79b2d3621ce8a4458
58 N3c89e833939e48e99f7545864be9b176 rdf:first sg:person.01064235363.82
59 rdf:rest Nb0f2a2f0ceef40439ece3adfea19e394
60 N5c8463c4458f44e79b2d3621ce8a4458 rdf:first sg:person.01233405241.45
61 rdf:rest rdf:nil
62 N682aa67165324becadac021bc775707b schema:name Springer Nature - SN SciGraph project
63 rdf:type schema:Organization
64 N7d0a396e63954b91a05408a09c7a72ee schema:issueNumber 1
65 rdf:type schema:PublicationIssue
66 N7ff98c069fda49df9556a6a9fc5209b4 rdf:first sg:person.060040255.77
67 rdf:rest N0f5b75d970c84796971d216968d7db83
68 Nb0f2a2f0ceef40439ece3adfea19e394 rdf:first sg:person.011462776151.76
69 rdf:rest N7ff98c069fda49df9556a6a9fc5209b4
70 Nb5f76b6732924ba59d19d333c77be7a2 schema:name dimensions_id
71 schema:value pub.1053278847
72 rdf:type schema:PropertyValue
73 Nc24d86e8edd24e4c98c56e54cb96f6fa schema:name doi
74 schema:value 10.1007/bf01054569
75 rdf:type schema:PropertyValue
76 Nf30aa21d89f3459496e42faeb761536e schema:volumeNumber 27
77 rdf:type schema:PublicationVolume
78 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
79 schema:name Medical and Health Sciences
80 rdf:type schema:DefinedTerm
81 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
82 schema:name Neurosciences
83 rdf:type schema:DefinedTerm
84 anzsrc-for:1116 schema:inDefinedTermSet anzsrc-for:
85 schema:name Medical Physiology
86 rdf:type schema:DefinedTerm
87 sg:journal.1016854 schema:issn 0090-2977
88 1573-9007
89 schema:name Neurophysiology
90 schema:publisher Springer Nature
91 rdf:type schema:Periodical
92 sg:person.01064235363.82 schema:affiliation grid-institutes:grid.418751.e
93 schema:familyName Kolchinskaya
94 schema:givenName L. I.
95 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064235363.82
96 rdf:type schema:Person
97 sg:person.011462776151.76 schema:affiliation grid-institutes:grid.418751.e
98 schema:familyName Kastrykina
99 schema:givenName T. F.
100 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011462776151.76
101 rdf:type schema:Person
102 sg:person.01233405241.45 schema:affiliation grid-institutes:grid.418751.e
103 schema:familyName Malysheva
104 schema:givenName M. K.
105 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233405241.45
106 rdf:type schema:Person
107 sg:person.015323536244.18 schema:affiliation grid-institutes:grid.419966.5
108 schema:familyName Terletskaya
109 schema:givenName Ya. T.
110 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015323536244.18
111 rdf:type schema:Person
112 sg:person.060040255.77 schema:affiliation grid-institutes:grid.419966.5
113 schema:familyName Trikash
114 schema:givenName I. O.
115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.060040255.77
116 rdf:type schema:Person
117 sg:pub.10.1007/bf01054256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044736490
118 https://doi.org/10.1007/bf01054256
119 rdf:type schema:CreativeWork
120 grid-institutes:grid.418751.e schema:alternateName Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine
121 schema:name Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine
122 rdf:type schema:Organization
123 grid-institutes:grid.419966.5 schema:alternateName Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine
124 schema:name Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine
125 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...