Effect of water activity on enzymatic synthesis of cephalexin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-08

AUTHORS

Chang K. Hyun, Jung H. Kim, Young J. Kim

ABSTRACT

In enzymatic synthesis of cephalexin (CEX) from 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D-α-phenylglycine methyl ester (PGM) using an acylase fromXanthomonas citri, it was found that the synthetic activity and conversion yield were enhanced markedly by depressing the water activity (aw) of reaction system. This enhancement was probably resulted from the change of thermodynamic equilibrium and maximized at a range ofaw from 0.96 to 0.97. More... »

PAGES

537-540

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01040031

DOI

http://dx.doi.org/10.1007/bf01040031

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028423051


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0305", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Organic Chemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Korea Advanced Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.37172.30", 
          "name": [
            "Department of Biological Science and Engineering, Korea. Advanced Institute of Science and Technology, Cheongyang, P.O.Box 150, 130-650, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hyun", 
        "givenName": "Chang K.", 
        "id": "sg:person.01174025640.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174025640.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Korea Advanced Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.37172.30", 
          "name": [
            "Department of Biological Science and Engineering, Korea. Advanced Institute of Science and Technology, Cheongyang, P.O.Box 150, 130-650, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Jung H.", 
        "id": "sg:person.01300137557.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300137557.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Korea Advanced Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.37172.30", 
          "name": [
            "Central Research Institute, Korea Steel Chemical Co., Ltd., 461-120, Sungnam, Korea", 
            "Department of Biological Science and Engineering, Korea. Advanced Institute of Science and Technology, Cheongyang, P.O.Box 150, 130-650, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Young J.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0141-0229(86)90129-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000033470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(86)90129-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000033470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(82)90094-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007131116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(82)90094-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007131116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(87)90123-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010296718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(87)90123-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010296718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.260270705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015353939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.260280106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028787368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(84)90006-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029346295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0141-0229(84)90006-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029346295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.260220610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047718511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.260230211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048888287"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1989-08", 
    "datePublishedReg": "1989-08-01", 
    "description": "In enzymatic synthesis of cephalexin (CEX) from 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D-\u03b1-phenylglycine methyl ester (PGM) using an acylase fromXanthomonas citri, it was found that the synthetic activity and conversion yield were enhanced markedly by depressing the water activity (aw) of reaction system. This enhancement was probably resulted from the change of thermodynamic equilibrium and maximized at a range ofaw from 0.96 to 0.97.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf01040031", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1289037", 
        "issn": [
          "0951-208X", 
          "1573-6784"
        ], 
        "name": "Biotechnology Letters", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "8", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "11"
      }
    ], 
    "name": "Effect of water activity on enzymatic synthesis of cephalexin", 
    "pagination": "537-540", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8766a36f9458cfee2cd232dfb4ffc9332c6819865644ca9419f48d8e1dfd7748"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf01040031"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1028423051"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf01040031", 
      "https://app.dimensions.ai/details/publication/pub.1028423051"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000495.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF01040031"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf01040031'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf01040031'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf01040031'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf01040031'


 

This table displays all metadata directly associated to this object as RDF triples.

99 TRIPLES      21 PREDICATES      35 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf01040031 schema:about anzsrc-for:03
2 anzsrc-for:0305
3 schema:author Ndc1ab05d7c5a410d8bcb7ef955656b22
4 schema:citation https://doi.org/10.1002/bit.260220610
5 https://doi.org/10.1002/bit.260230211
6 https://doi.org/10.1002/bit.260270705
7 https://doi.org/10.1002/bit.260280106
8 https://doi.org/10.1016/0141-0229(82)90094-1
9 https://doi.org/10.1016/0141-0229(84)90006-1
10 https://doi.org/10.1016/0141-0229(86)90129-8
11 https://doi.org/10.1016/0141-0229(87)90123-2
12 schema:datePublished 1989-08
13 schema:datePublishedReg 1989-08-01
14 schema:description In enzymatic synthesis of cephalexin (CEX) from 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D-α-phenylglycine methyl ester (PGM) using an acylase fromXanthomonas citri, it was found that the synthetic activity and conversion yield were enhanced markedly by depressing the water activity (aw) of reaction system. This enhancement was probably resulted from the change of thermodynamic equilibrium and maximized at a range ofaw from 0.96 to 0.97.
15 schema:genre research_article
16 schema:inLanguage en
17 schema:isAccessibleForFree false
18 schema:isPartOf N411432cef23142b7b1705942aff1b2b1
19 Nc9546573649f47f792325b725ce7c138
20 sg:journal.1289037
21 schema:name Effect of water activity on enzymatic synthesis of cephalexin
22 schema:pagination 537-540
23 schema:productId N3bf1aaf6b1ef41c3913ec0e38666c768
24 N42eba965c90d43ea9bf5fb8e575ae846
25 Nc1f16452c5dd413bbddeb19ee4333486
26 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028423051
27 https://doi.org/10.1007/bf01040031
28 schema:sdDatePublished 2019-04-11T00:12
29 schema:sdLicense https://scigraph.springernature.com/explorer/license/
30 schema:sdPublisher N715982c572a544ce81d4e3d36dce02cf
31 schema:url http://link.springer.com/10.1007/BF01040031
32 sgo:license sg:explorer/license/
33 sgo:sdDataset articles
34 rdf:type schema:ScholarlyArticle
35 N0283b0ee66464215b1d7f21ea3b4f97f rdf:first N3d4052d884434e4e864b4156f8c50b5d
36 rdf:rest rdf:nil
37 N3bf1aaf6b1ef41c3913ec0e38666c768 schema:name doi
38 schema:value 10.1007/bf01040031
39 rdf:type schema:PropertyValue
40 N3d4052d884434e4e864b4156f8c50b5d schema:affiliation https://www.grid.ac/institutes/grid.37172.30
41 schema:familyName Kim
42 schema:givenName Young J.
43 rdf:type schema:Person
44 N411432cef23142b7b1705942aff1b2b1 schema:volumeNumber 11
45 rdf:type schema:PublicationVolume
46 N42eba965c90d43ea9bf5fb8e575ae846 schema:name dimensions_id
47 schema:value pub.1028423051
48 rdf:type schema:PropertyValue
49 N44c4c17ad04e47898c2c55262a75b394 rdf:first sg:person.01300137557.41
50 rdf:rest N0283b0ee66464215b1d7f21ea3b4f97f
51 N715982c572a544ce81d4e3d36dce02cf schema:name Springer Nature - SN SciGraph project
52 rdf:type schema:Organization
53 Nc1f16452c5dd413bbddeb19ee4333486 schema:name readcube_id
54 schema:value 8766a36f9458cfee2cd232dfb4ffc9332c6819865644ca9419f48d8e1dfd7748
55 rdf:type schema:PropertyValue
56 Nc9546573649f47f792325b725ce7c138 schema:issueNumber 8
57 rdf:type schema:PublicationIssue
58 Ndc1ab05d7c5a410d8bcb7ef955656b22 rdf:first sg:person.01174025640.51
59 rdf:rest N44c4c17ad04e47898c2c55262a75b394
60 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
61 schema:name Chemical Sciences
62 rdf:type schema:DefinedTerm
63 anzsrc-for:0305 schema:inDefinedTermSet anzsrc-for:
64 schema:name Organic Chemistry
65 rdf:type schema:DefinedTerm
66 sg:journal.1289037 schema:issn 0951-208X
67 1573-6784
68 schema:name Biotechnology Letters
69 rdf:type schema:Periodical
70 sg:person.01174025640.51 schema:affiliation https://www.grid.ac/institutes/grid.37172.30
71 schema:familyName Hyun
72 schema:givenName Chang K.
73 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174025640.51
74 rdf:type schema:Person
75 sg:person.01300137557.41 schema:affiliation https://www.grid.ac/institutes/grid.37172.30
76 schema:familyName Kim
77 schema:givenName Jung H.
78 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300137557.41
79 rdf:type schema:Person
80 https://doi.org/10.1002/bit.260220610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047718511
81 rdf:type schema:CreativeWork
82 https://doi.org/10.1002/bit.260230211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048888287
83 rdf:type schema:CreativeWork
84 https://doi.org/10.1002/bit.260270705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015353939
85 rdf:type schema:CreativeWork
86 https://doi.org/10.1002/bit.260280106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028787368
87 rdf:type schema:CreativeWork
88 https://doi.org/10.1016/0141-0229(82)90094-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007131116
89 rdf:type schema:CreativeWork
90 https://doi.org/10.1016/0141-0229(84)90006-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029346295
91 rdf:type schema:CreativeWork
92 https://doi.org/10.1016/0141-0229(86)90129-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000033470
93 rdf:type schema:CreativeWork
94 https://doi.org/10.1016/0141-0229(87)90123-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010296718
95 rdf:type schema:CreativeWork
96 https://www.grid.ac/institutes/grid.37172.30 schema:alternateName Korea Advanced Institute of Science and Technology
97 schema:name Central Research Institute, Korea Steel Chemical Co., Ltd., 461-120, Sungnam, Korea
98 Department of Biological Science and Engineering, Korea. Advanced Institute of Science and Technology, Cheongyang, P.O.Box 150, 130-650, Seoul, Korea
99 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...