Chronische lymphoproliferative Erkrankung unter dem Bild einer Haarzell-Leukämie View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-06

AUTHORS

Ingrid Fohlmeister, H. -E. Schaefer, B. Mödder, K. -P. Hellriegel, R. Fischer

ABSTRACT

Seven patients are presented with a chronic lymphoproliferative disorder characterized clinically by splenomegaly, no or discrete lymphnode enlargement, and a varying degree of cytopenia. In blood and bone-marrow smears lymphoid cells of “hairy” appearance are demonstrable which may contain tartrate-resistant acid phosphatase. The finding of a nodular bone-marrow infiltration without fibrosis as well as that of a nodular infiltration of the spleen originating in the white pulp are incompatible with the diagnosis hairy-cell leukemia and place the disease near to chronic lymphocytic leukemia (CLL) or leukemic immunocytoma respectively. A detailed cytologic and cytochemical examination of the infiltrating cells shows deviations from the typical enzymatic pattern of hairy cells and from known enzymatic constellations in CLL and related lymphoproliferative disorders. Thus, we are dealing with an intermediate form, difficult to classify, the separation of which nevertheless seems to be important for therapeutical reasons. More... »

PAGES

367-377

References to SciGraph publications

  • 1978. Histopathology and Diagnosis of Non-Hodgkin’s Lymphomas in MALIGNANT LYMPHOMAS OTHER THAN HODGKIN’S DISEASE
  • 1975-12. Zytochemischer Polymorphismus der sauren Phosphatase bei Haarzell-Leukämie in BLUT ZEITSCHRIFT FÜR DIE GESAMTE BLUTFORSCHUNG
  • 1968-11. Der Peroxydasenachweis an Ausstrichpräparaten sowie an Gewebsschnitten nach Entkalkung und Paraffineinbettung in JOURNAL OF MOLECULAR MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00996899

    DOI

    http://dx.doi.org/10.1007/bf00996899

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1039859035

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7248528


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