Treatment of chronic urticaria with terfenadine and ranitidine View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-05

AUTHORS

E. Paul, R. H. Bödeker

ABSTRACT

45 patients with chronic urticaria were randomized to double blind therapy with terfenadine an H1-antihistamine or ranitidine, an H2-antihistamine, or a combination of both drugs. The therapeutic response was assessed by diary scores. The primary effect variable was "itching". The inference-statistical evaluation of the patient scores showed varying therapeutic effects. The Type-I error was p = 0.015. Itching was reported to be significantly lower by patients receiving both drugs than by those who were given terfenadine alone, while ranitidine in monotherapy had no significant effect on itching. A similar trend was seen in assessment of the severity of weals, while the treatment regimens had no influence on swelling. More... »

PAGES

277-280

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00981123

DOI

http://dx.doi.org/10.1007/bf00981123

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021715265

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2878811


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