Glutathione peroxidase activity in surgical and autopsied human brains View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-05

AUTHORS

K. A. Ansari, D. Bigelow, Eli Kaplan

ABSTRACT

Glutathione peroxidase (GSHPx) activity was assayed in normal cerebral gray and white matter samples obtained from frontal, temporal, occipital and parietal lobes during surgical approach to an underlying lesion, and also in normal autopsied human frontal gray and white matter. GSHPx was assayed by a 2 step enzyme reaction which was monitored by following the oxidation of NADPH at 340 nm. It was found that all the brain samples studied contained GSHPx activity. Parietal lobe appeared to have the lowest GSHPx activity compared to temporal, occipital or frontal lobes. Mean enzyme activity in autopsied samples was comparable to that in surgical material. However, considerable loss of activity was observed after 10 years of tissue storage at -80 degrees C. More... »

PAGES

703-711

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00964408

DOI

http://dx.doi.org/10.1007/bf00964408

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001440920

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4010876


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