Ontology type: schema:ScholarlyArticle
1990-12
AUTHORSA. Mazzone, G. Ricevuti, D. Pasotti, A. Fioravanti, M. Marcoli, S. Lecchini, A. Notario, G. M. Frigo
ABSTRACTMorphine was found to inhibit human granulocyte aggregation and ATP, thromboxane B2 (TxB2), and leukotriene B4 (LTB4) secretion during cell aggregation. None of the opioid peptides tested [(D-Ala2, D-Leu5)-enkephalin (DADL), (D-Ala2, N-Me-Phe4, Gly-ol5)-enkephalin (DAGO) or dynorphin 1-9 (Dyn 1-9)] was capable of mimicking morphine effects, while Dyn 1-9 per se induced TxB2 and LTB4 secretion from granulocytes. Morphine inhibition of both cell aggregation and ATP, but not of arachidonic acid metabolism product secretion, was prevented by naloxone. The naloxone-sensitive impairment by morphine of CD11b-CD18 complex surface expression observed could play a role in opioid inhibition of granulocyte activation. More... »
PAGES717-726
http://scigraph.springernature.com/pub.10.1007/bf00916374
DOIhttp://dx.doi.org/10.1007/bf00916374
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1035132516
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/1982531
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adenosine Triphosphate",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antigens, Differentiation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "CD11 Antigens",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "CD18 Antigens",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Aggregation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Depression, Chemical",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Endorphins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Leukotriene B4",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Morphine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Naloxone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neutrophils",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Leukocyte-Adhesion",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Thromboxane B2",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Mazzone",
"givenName": "A.",
"id": "sg:person.01001462274.33",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01001462274.33"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Ricevuti",
"givenName": "G.",
"id": "sg:person.01346746705.63",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346746705.63"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Pasotti",
"givenName": "D.",
"id": "sg:person.01154543063.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154543063.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Fioravanti",
"givenName": "A.",
"id": "sg:person.01036161452.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036161452.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Marcoli",
"givenName": "M.",
"id": "sg:person.01344075117.84",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344075117.84"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Lecchini",
"givenName": "S.",
"id": "sg:person.01005474424.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005474424.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Notario",
"givenName": "A.",
"id": "sg:person.0110227707.51",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0110227707.51"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pavia",
"id": "https://www.grid.ac/institutes/grid.8982.b",
"name": [
"Department of Internal Medicine and Therapeutics Section of Medical Pathology and Section of Pharmacology, University of Pavia IRCCS San Matteo Hospital, P. le Golgi 2, 27100, Pavia, Italy"
],
"type": "Organization"
},
"familyName": "Frigo",
"givenName": "G. M.",
"id": "sg:person.01320403767.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320403767.18"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/0006-2952(80)90431-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000284552"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0006-2952(80)90431-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000284552"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.2042-7158.1985.tb05015.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002362844"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-1-4899-0557-4_17",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002409758",
"https://doi.org/10.1007/978-1-4899-0557-4_17"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0143-4179(85)90029-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006607761"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(88)90383-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009715692"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(88)90383-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009715692"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0167-5699(85)90181-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012454794"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(82)90054-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015605095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(82)90054-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015605095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-2697(76)90527-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025529346"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(87)90405-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026026017"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(87)90405-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026026017"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0165-5728(87)90117-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028260086"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0165-5728(87)90117-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028260086"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(85)90076-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030458920"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(85)90076-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030458920"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0309-1651(86)90038-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030785757"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0090-1229(86)90109-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032160058"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0171-2985(85)80007-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032264379"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0192-0561(89)90099-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032732585"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0192-0561(89)90099-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032732585"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-1-4899-0557-4_27",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034457694",
"https://doi.org/10.1007/978-1-4899-0557-4_27"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0192-0561(88)90129-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034656587"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0192-0561(88)90129-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034656587"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00914930",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035488064",
"https://doi.org/10.1007/bf00914930"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1172/jci108763",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037844888"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(84)90213-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046065389"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(84)90213-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046065389"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cyto.990030404",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050703892"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cyto.990030404",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050703892"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(83)90608-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053339489"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0024-3205(83)90608-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053339489"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.224457",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062528861"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/endo-117-2-793",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064259070"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/endo-117-4-1389",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064259170"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078531903",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078810191",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079492092",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079495710",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079519123",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079576743",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079660946",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079716490",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080058319",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080173643",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081668205",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081681400",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081702052",
"type": "CreativeWork"
}
],
"datePublished": "1990-12",
"datePublishedReg": "1990-12-01",
"description": "Morphine was found to inhibit human granulocyte aggregation and ATP, thromboxane B2 (TxB2), and leukotriene B4 (LTB4) secretion during cell aggregation. None of the opioid peptides tested [(D-Ala2, D-Leu5)-enkephalin (DADL), (D-Ala2, N-Me-Phe4, Gly-ol5)-enkephalin (DAGO) or dynorphin 1-9 (Dyn 1-9)] was capable of mimicking morphine effects, while Dyn 1-9 per se induced TxB2 and LTB4 secretion from granulocytes. Morphine inhibition of both cell aggregation and ATP, but not of arachidonic acid metabolism product secretion, was prevented by naloxone. The naloxone-sensitive impairment by morphine of CD11b-CD18 complex surface expression observed could play a role in opioid inhibition of granulocyte activation.",
"genre": "research_article",
"id": "sg:pub.10.1007/bf00916374",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1084792",
"issn": [
"0360-3997",
"1573-2576"
],
"name": "Inflammation",
"type": "Periodical"
},
{
"issueNumber": "6",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "14"
}
],
"name": "Peptide opioids and morphine effects on inflammatory process",
"pagination": "717-726",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"a75be84d98c219f1ee025d3309d7e64eac5658dfe5eb55200d63df933d53565e"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"1982531"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"7600105"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf00916374"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1035132516"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf00916374",
"https://app.dimensions.ai/details/publication/pub.1035132516"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T23:17",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000482.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/BF00916374"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00916374'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00916374'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00916374'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00916374'
This table displays all metadata directly associated to this object as RDF triples.
278 TRIPLES
21 PREDICATES
81 URIs
35 LITERALS
23 BLANK NODES