Proton magnetic resonance spectroscopy and intracranial tumours: Clinical perspectives View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-10

AUTHORS

Andrea Falini, Giovanna Calabrese, Daniela Origgi, Susanna Lipari, Fabio Triulzi, Marco Losa, Giuseppe Scotti

ABSTRACT

Proton magnetic resonance spectroscopy (1H-MRS) was applied to characterize intracranial tumours of different hystological types. Seventy patients with intracranial neoplasms were studied before receiving surgery, radiotherapy or chemotherapy. All tumours were characterized by reduced or absent N-acetylasparate and increased signal from choline-containing compounds. Distinctive patterns were observed only for primitive brain neoplasms; high-grade gliomas were differentiated from low-grade ones by higher levels of choline-containing compounds. The metabolic aspects of metastatic lesions were similar to high-grade gliomas. These results, together with the limitations of 1H-MRS and future applications are reviewed. More... »

PAGES

706-714

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00873976

DOI

http://dx.doi.org/10.1007/bf00873976

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018811705

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8923303


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