Phase II evaluation of piroxantrone in renal cell carcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-06

AUTHORS

Ace Allen, Michael Wolf, E. David Crawford, Mellar P. Davis, Ronald B. Natale, Margaret L. Barnett

ABSTRACT

The Southwest Oncology Group (SWOG) studied the response rate and toxicity of piroxantrone (150 mg/m2 q 21 days) in patients with advanced metastatic renal cell carcinoma. Among 32 eligible patients, there were no partial nor complete responses. There were two mixed responses. Significant white cell toxicity, anemia, nausea, and vomiting were observed. Mild or moderate degrees of fever, malaise, and stomatitis occurred. No significant cardiac toxicity was noted. Piroxantrone does not have significant activity as a single agent in advanced renal cell carcinoma. More... »

PAGES

129-132

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00873131

DOI

http://dx.doi.org/10.1007/bf00873131

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015657934

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1500267


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