Treatment with a combination of low-density lipoprotein aphaeresis and pravastatin of a patient with drug-resistant nephrotic syndrome due to focal ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1993-04

AUTHORS

Motoshi Hattori, Katsumi Ito, Hiroshi Kawaguchi, Toshihisa Tanaka, Reiko Kubota, Miyuki Khono

ABSTRACT

Results of recent animal studies have lent support to the hypothesis that hyperlipidaemia may contribute to renal injury. This report documents the case of a 15-year-old boy with drug-resistant nephrotic syndrome due to focal segmental glomerulosclerosis (FGS) who showed an improvement in renal function and proteinuria as a result of treatment with low-density lipoprotein aphaeresis (LDL-A) combined with pravastatin. Although further work is required to determine the efficacy of lipidlowering therapy in progressive glomerular disease in humans, the combination of LDL-A and pravastatin is likely be included in the choice of treatment modalities available for patients with drug-resistant nephrotic syndrome due to FGS. More... »

PAGES

196-198

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00864397

DOI

http://dx.doi.org/10.1007/bf00864397

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048455776

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8476719


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