Rate of deterioration of renal function in juvenile nephronophthisis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-03

AUTHORS

Norbert Gretz, Karl Schärer, Rüdiger Waldherr, Manfred Strauch

ABSTRACT

The rate of deterioration of renal function was determined in 29 patients with juvenile nephronophthisis presenting before the age of 18.5 years. The analysis was based on 618 serial determinations of serum creatinine (SCR). By application of a new statistical method the time elapsing between different successive SCR levels was calculated. A more or less homogeneous increase of SCR was noted starting from the time when a SCR of 4 mg/dl was reached. The median time elapsing between an SCR of 2 and 4 mg/dl was 32 months, between 4 and 6 mg/dl 10 months and between 6 and 8 mg/dl 5 months. The median age at the start of renal replacement therapy or death due to uraemia, evaluated by survival analysis, was similar in both sexes. More... »

PAGES

56-60

References to SciGraph publications

  • 1982. The Nephronophthisis Complex; a Clinicopathologic Study in RENAL INSUFFICIENCY IN CHILDREN
  • 1982-01. The nephronophthisis complex in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • 1987-09. Ocular changes in some progressive hereditary nephropathies in PEDIATRIC NEPHROLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00859627

    DOI

    http://dx.doi.org/10.1007/bf00859627

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1016589186

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2702089


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