Timing and heritability of theNasobemia transformation inDrosophila View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1980-06

AUTHORS

Stuart Alan Kauffman, Elizabeth Ling

ABSTRACT

Nasobemia (Ns) is a dominant homeotic mutant ofDrosophila melanogaster which converts parts or all of the antenna to mesothoracic leg.Ns has a temperature sensitive period between 48 and 60 h. The hypothesis thatNs acts during this period and is not required thereafter to maintain the homeotic transformation to leg was tested by removingNs fromNs/+ cells at different stages of development through X-ray induced somatic recombination. The expression of theNs homeotic transformation in recombinant wild type (+/+) cells increased sharply between 48 and 65 h. In clones induced after 65 h the expression of the leg transformation was equal in large and small +/+ clones. We interpret these results as supporting the hypothesis that transient action ofNs between 48 and 65 h switches antennal cells to a clonally stable leg determined state whose maintenance does not require futherNs action. More... »

PAGES

147-153

Journal

TITLE

Development Genes and Evolution

ISSUE

2

VOLUME

189

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00848503

DOI

http://dx.doi.org/10.1007/bf00848503

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034233092

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28304963


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