Effects of 2-chloropropionate on venous plasma lactate concentration and anaerobic power during periods of incremental intensive exercise in humans View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-09

AUTHORS

B. Mercier, P. Granier, J. Mercier, F. Anselme, G. Ribes, C. Préfaut

ABSTRACT

We investigated the effects of a stimulation of pyruvate dehydrogenase (PDH) activity induced by 2-chloropropionate (2-CP) on venous plasma lactate concentration and peak anaerobic power (W an, peak) during periods (6 s) of incremental intense exercise, i.e. a force-velocity (F-v) test known to induce a marked accumulation of lactate in the blood. The F-v test was performed twice by six subjects according to a double-blind randomized crossover protocol: once with placebo and once with 2-CP (43 mg.kg-1 body mass). Blood samples were taken at ingestion of the drug, at 10, 20, and 40 min into the pretest period, at the end of each period of intense exercise, at the end of each 5-min recovery period, and after completion of the F-v test at 5, 10, 15, and 30 min. During the F-v test, venous plasma lactate concentrations with both placebo and 2-CP increased significantly when measured at the end of each period of intense exercise (F = 33.5, P < 0.001), and each 5-min recovery period (F = 24.6, P < 0.001). Venous plasma lactate concentrations were significantly lower with 2-CP at the end of each recovery period (P < 0.01), especially for high braking forces, i.e. 8 kg (P < 0.05), 9 kg (P < 0.02), and maximal braking force (P < 0.05). After completion of the F-v test, venous plasma lactate concentrations were also significantly lower with 2-CP (P < 0.001). The percentage of lactate decrease between 5- and 30-min recovery was significantly higher with 2-CP than with the placebo [59 (SEM 4)% vs 44.6 (SEM 5.5)%, P < 0.05]. Furthermore, W an, peak was significantly higher with 2-CP than with the placebo [1016 (SEM 60) W vs 957 (SEM 55) W, P < 0.05]. In conclusion, PDH activation by 2-CP attenuated the increase in venous plasma lactate concentration during the F-v test. Ingestion of 2-CP led to an increased W an, peak. More... »

PAGES

425-429

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00843740

DOI

http://dx.doi.org/10.1007/bf00843740

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002901444

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8076623


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anaerobic Threshold", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrocarbons, Chlorinated", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lactates", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lactic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Physical Exertion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Propionates", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, H\u00f4pital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mercier", 
        "givenName": "B.", 
        "id": "sg:person.0771440045.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771440045.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, H\u00f4pital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Granier", 
        "givenName": "P.", 
        "id": "sg:person.0773261550.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773261550.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, H\u00f4pital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mercier", 
        "givenName": "J.", 
        "id": "sg:person.01224223443.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224223443.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, H\u00f4pital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anselme", 
        "givenName": "F.", 
        "id": "sg:person.01276647616.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276647616.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Laboratoire de Pharmacologie, Institut de Biologic, Boulevard Henri IV, F-34059, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ribes", 
        "givenName": "G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Arnaud De Villeneuve", 
          "id": "https://www.grid.ac/institutes/grid.413745.0", 
          "name": [
            "Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, H\u00f4pital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pr\u00e9faut", 
        "givenName": "C.", 
        "id": "sg:person.014517744274.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014517744274.16"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00599623", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000545645", 
          "https://doi.org/10.1007/bf00599623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00599623", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000545645", 
          "https://doi.org/10.1007/bf00599623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00424805", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005181373", 
          "https://doi.org/10.1007/bf00424805"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/00140138608968287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009428916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1341067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010039604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1341067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010039604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/00005768-198708000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011416947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1748-1716.1992.tb09264.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025835816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci110682", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029312954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.1910200107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033082639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198308183090702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036349513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/00005768-199008000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039147413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1410761", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041874000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1410761", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041874000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00237786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045148764", 
          "https://doi.org/10.1007/bf00237786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00237786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045148764", 
          "https://doi.org/10.1007/bf00237786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci112090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048027077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(82)91364-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051355578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01799655", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052471770", 
          "https://doi.org/10.1007/bf01799655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf01799655", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052471770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(79)90405-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052613509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-1024648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057495499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.28.9.852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070733550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1992.72.2.590", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1076980134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1991.70.3.1031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078131414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078381873", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1990.69.3.1165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078539870"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.1989.66.2.591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079257869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079298692", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079924872", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082148610", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082362258", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1994-09", 
    "datePublishedReg": "1994-09-01", 
    "description": "We investigated the effects of a stimulation of pyruvate dehydrogenase (PDH) activity induced by 2-chloropropionate (2-CP) on venous plasma lactate concentration and peak anaerobic power (W an, peak) during periods (6 s) of incremental intense exercise, i.e. a force-velocity (F-v) test known to induce a marked accumulation of lactate in the blood. The F-v test was performed twice by six subjects according to a double-blind randomized crossover protocol: once with placebo and once with 2-CP (43 mg.kg-1 body mass). Blood samples were taken at ingestion of the drug, at 10, 20, and 40 min into the pretest period, at the end of each period of intense exercise, at the end of each 5-min recovery period, and after completion of the F-v test at 5, 10, 15, and 30 min. During the F-v test, venous plasma lactate concentrations with both placebo and 2-CP increased significantly when measured at the end of each period of intense exercise (F = 33.5, P < 0.001), and each 5-min recovery period (F = 24.6, P < 0.001). Venous plasma lactate concentrations were significantly lower with 2-CP at the end of each recovery period (P < 0.01), especially for high braking forces, i.e. 8 kg (P < 0.05), 9 kg (P < 0.02), and maximal braking force (P < 0.05). After completion of the F-v test, venous plasma lactate concentrations were also significantly lower with 2-CP (P < 0.001). The percentage of lactate decrease between 5- and 30-min recovery was significantly higher with 2-CP than with the placebo [59 (SEM 4)% vs 44.6 (SEM 5.5)%, P < 0.05]. Furthermore, W an, peak was significantly higher with 2-CP than with the placebo [1016 (SEM 60) W vs 957 (SEM 55) W, P < 0.05]. In conclusion, PDH activation by 2-CP attenuated the increase in venous plasma lactate concentration during the F-v test. Ingestion of 2-CP led to an increased W an, peak.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00843740", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1319730", 
        "issn": [
          "1439-6319", 
          "1432-1025"
        ], 
        "name": "European Journal of Applied Physiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "68"
      }
    ], 
    "name": "Effects of 2-chloropropionate on venous plasma lactate concentration and anaerobic power during periods of incremental intensive exercise in humans", 
    "pagination": "425-429", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "0dd19cb33453cbe14bae0e001e0d96a6d78b396c014481d1fe3073a7442abb73"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8076623"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410266"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00843740"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1002901444"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00843740", 
      "https://app.dimensions.ai/details/publication/pub.1002901444"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T13:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000530.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2FBF00843740"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00843740'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00843740'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00843740'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00843740'


 

This table displays all metadata directly associated to this object as RDF triples.

224 TRIPLES      21 PREDICATES      66 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00843740 schema:about N05cc191c6c274f9a8946e130f5935eab
2 N5621f765687b44eaa9d5a8a496b4b75a
3 N6b23f35ebee8486d8d74694c7afda39b
4 N8539ce4cf3a94e60ad8f31992a0192e5
5 Na1bac908ccf445c5beab93ac11b2bd41
6 Nbef5eaa545df402c9a3490eda45b647e
7 Nde9761615f794ee2bdf370eafa0d0a44
8 Ne9ff5a1269c04a969aa634521b46d9da
9 Nfef6ba8437dd4125bf112ca9fe40e7a9
10 anzsrc-for:11
11 anzsrc-for:1103
12 schema:author Nb58079c650d64c4baf35515c78450ff4
13 schema:citation sg:pub.10.1007/bf00237786
14 sg:pub.10.1007/bf00424805
15 sg:pub.10.1007/bf00599623
16 sg:pub.10.1007/bf01799655
17 https://app.dimensions.ai/details/publication/pub.1078381873
18 https://app.dimensions.ai/details/publication/pub.1079298692
19 https://app.dimensions.ai/details/publication/pub.1079924872
20 https://app.dimensions.ai/details/publication/pub.1082148610
21 https://app.dimensions.ai/details/publication/pub.1082362258
22 https://doi.org/10.1002/mrm.1910200107
23 https://doi.org/10.1007/bf01799655
24 https://doi.org/10.1016/0003-9861(79)90405-3
25 https://doi.org/10.1016/0006-291x(82)91364-x
26 https://doi.org/10.1042/bj1341067
27 https://doi.org/10.1042/bj1410761
28 https://doi.org/10.1055/s-2007-1024648
29 https://doi.org/10.1056/nejm198308183090702
30 https://doi.org/10.1080/00140138608968287
31 https://doi.org/10.1111/j.1748-1716.1992.tb09264.x
32 https://doi.org/10.1152/jappl.1989.66.2.591
33 https://doi.org/10.1152/jappl.1990.69.3.1165
34 https://doi.org/10.1152/jappl.1991.70.3.1031
35 https://doi.org/10.1152/jappl.1992.72.2.590
36 https://doi.org/10.1172/jci110682
37 https://doi.org/10.1172/jci112090
38 https://doi.org/10.1249/00005768-198708000-00015
39 https://doi.org/10.1249/00005768-199008000-00004
40 https://doi.org/10.2337/diab.28.9.852
41 schema:datePublished 1994-09
42 schema:datePublishedReg 1994-09-01
43 schema:description We investigated the effects of a stimulation of pyruvate dehydrogenase (PDH) activity induced by 2-chloropropionate (2-CP) on venous plasma lactate concentration and peak anaerobic power (W an, peak) during periods (6 s) of incremental intense exercise, i.e. a force-velocity (F-v) test known to induce a marked accumulation of lactate in the blood. The F-v test was performed twice by six subjects according to a double-blind randomized crossover protocol: once with placebo and once with 2-CP (43 mg.kg-1 body mass). Blood samples were taken at ingestion of the drug, at 10, 20, and 40 min into the pretest period, at the end of each period of intense exercise, at the end of each 5-min recovery period, and after completion of the F-v test at 5, 10, 15, and 30 min. During the F-v test, venous plasma lactate concentrations with both placebo and 2-CP increased significantly when measured at the end of each period of intense exercise (F = 33.5, P < 0.001), and each 5-min recovery period (F = 24.6, P < 0.001). Venous plasma lactate concentrations were significantly lower with 2-CP at the end of each recovery period (P < 0.01), especially for high braking forces, i.e. 8 kg (P < 0.05), 9 kg (P < 0.02), and maximal braking force (P < 0.05). After completion of the F-v test, venous plasma lactate concentrations were also significantly lower with 2-CP (P < 0.001). The percentage of lactate decrease between 5- and 30-min recovery was significantly higher with 2-CP than with the placebo [59 (SEM 4)% vs 44.6 (SEM 5.5)%, P < 0.05]. Furthermore, W an, peak was significantly higher with 2-CP than with the placebo [1016 (SEM 60) W vs 957 (SEM 55) W, P < 0.05]. In conclusion, PDH activation by 2-CP attenuated the increase in venous plasma lactate concentration during the F-v test. Ingestion of 2-CP led to an increased W an, peak.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf N6af4177a6ca2453fbf31eb5fba17d82a
48 Nac4d3e3d3da24125a288eb8941650e7f
49 sg:journal.1319730
50 schema:name Effects of 2-chloropropionate on venous plasma lactate concentration and anaerobic power during periods of incremental intensive exercise in humans
51 schema:pagination 425-429
52 schema:productId N6900b4d55cd84dd29dba3b3e13f3ba57
53 N6c213b2ccbec4271b1da71d82d10bad5
54 N7a9f4c7b6d52482583719265488e2522
55 N915a519eb40b494c8b78a87a687a1b0e
56 N984539dbb17d4834b88001d2f7923350
57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002901444
58 https://doi.org/10.1007/bf00843740
59 schema:sdDatePublished 2019-04-10T13:21
60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
61 schema:sdPublisher N42e77bbd52e14f42b33828efc57fd205
62 schema:url http://link.springer.com/10.1007%2FBF00843740
63 sgo:license sg:explorer/license/
64 sgo:sdDataset articles
65 rdf:type schema:ScholarlyArticle
66 N05cc191c6c274f9a8946e130f5935eab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
67 schema:name Propionates
68 rdf:type schema:DefinedTerm
69 N0d0a9871d43246619d1d7bd36fd3f7bf rdf:first sg:person.0773261550.94
70 rdf:rest N27841b8dafb24adb950074e5ac45001b
71 N1384f335113c4fe8918b9112d1f72c56 schema:affiliation N4c48a9eb352e405b8a2dc4447557b7c8
72 schema:familyName Ribes
73 schema:givenName G.
74 rdf:type schema:Person
75 N27841b8dafb24adb950074e5ac45001b rdf:first sg:person.01224223443.00
76 rdf:rest Nf097e39a1d544ca481786d2c185def24
77 N42e77bbd52e14f42b33828efc57fd205 schema:name Springer Nature - SN SciGraph project
78 rdf:type schema:Organization
79 N4c48a9eb352e405b8a2dc4447557b7c8 schema:name Laboratoire de Pharmacologie, Institut de Biologic, Boulevard Henri IV, F-34059, Montpellier, France
80 rdf:type schema:Organization
81 N5621f765687b44eaa9d5a8a496b4b75a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Male
83 rdf:type schema:DefinedTerm
84 N6900b4d55cd84dd29dba3b3e13f3ba57 schema:name nlm_unique_id
85 schema:value 0410266
86 rdf:type schema:PropertyValue
87 N6af4177a6ca2453fbf31eb5fba17d82a schema:issueNumber 5
88 rdf:type schema:PublicationIssue
89 N6b23f35ebee8486d8d74694c7afda39b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Adult
91 rdf:type schema:DefinedTerm
92 N6c213b2ccbec4271b1da71d82d10bad5 schema:name readcube_id
93 schema:value 0dd19cb33453cbe14bae0e001e0d96a6d78b396c014481d1fe3073a7442abb73
94 rdf:type schema:PropertyValue
95 N712b59441b2e4f30b2f8f325fb35e6a3 rdf:first sg:person.014517744274.16
96 rdf:rest rdf:nil
97 N7a9f4c7b6d52482583719265488e2522 schema:name pubmed_id
98 schema:value 8076623
99 rdf:type schema:PropertyValue
100 N8539ce4cf3a94e60ad8f31992a0192e5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Lactates
102 rdf:type schema:DefinedTerm
103 N915a519eb40b494c8b78a87a687a1b0e schema:name doi
104 schema:value 10.1007/bf00843740
105 rdf:type schema:PropertyValue
106 N984539dbb17d4834b88001d2f7923350 schema:name dimensions_id
107 schema:value pub.1002901444
108 rdf:type schema:PropertyValue
109 Na1bac908ccf445c5beab93ac11b2bd41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Humans
111 rdf:type schema:DefinedTerm
112 Na3f5f163cb1e419a93c4c035e460b40e rdf:first N1384f335113c4fe8918b9112d1f72c56
113 rdf:rest N712b59441b2e4f30b2f8f325fb35e6a3
114 Nac4d3e3d3da24125a288eb8941650e7f schema:volumeNumber 68
115 rdf:type schema:PublicationVolume
116 Nb58079c650d64c4baf35515c78450ff4 rdf:first sg:person.0771440045.75
117 rdf:rest N0d0a9871d43246619d1d7bd36fd3f7bf
118 Nbef5eaa545df402c9a3490eda45b647e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Physical Exertion
120 rdf:type schema:DefinedTerm
121 Nde9761615f794ee2bdf370eafa0d0a44 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Hydrocarbons, Chlorinated
123 rdf:type schema:DefinedTerm
124 Ne9ff5a1269c04a969aa634521b46d9da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Anaerobic Threshold
126 rdf:type schema:DefinedTerm
127 Nf097e39a1d544ca481786d2c185def24 rdf:first sg:person.01276647616.44
128 rdf:rest Na3f5f163cb1e419a93c4c035e460b40e
129 Nfef6ba8437dd4125bf112ca9fe40e7a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Lactic Acid
131 rdf:type schema:DefinedTerm
132 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
133 schema:name Medical and Health Sciences
134 rdf:type schema:DefinedTerm
135 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
136 schema:name Clinical Sciences
137 rdf:type schema:DefinedTerm
138 sg:journal.1319730 schema:issn 1432-1025
139 1439-6319
140 schema:name European Journal of Applied Physiology
141 rdf:type schema:Periodical
142 sg:person.01224223443.00 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
143 schema:familyName Mercier
144 schema:givenName J.
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224223443.00
146 rdf:type schema:Person
147 sg:person.01276647616.44 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
148 schema:familyName Anselme
149 schema:givenName F.
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276647616.44
151 rdf:type schema:Person
152 sg:person.014517744274.16 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
153 schema:familyName Préfaut
154 schema:givenName C.
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014517744274.16
156 rdf:type schema:Person
157 sg:person.0771440045.75 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
158 schema:familyName Mercier
159 schema:givenName B.
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771440045.75
161 rdf:type schema:Person
162 sg:person.0773261550.94 schema:affiliation https://www.grid.ac/institutes/grid.413745.0
163 schema:familyName Granier
164 schema:givenName P.
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773261550.94
166 rdf:type schema:Person
167 sg:pub.10.1007/bf00237786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045148764
168 https://doi.org/10.1007/bf00237786
169 rdf:type schema:CreativeWork
170 sg:pub.10.1007/bf00424805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005181373
171 https://doi.org/10.1007/bf00424805
172 rdf:type schema:CreativeWork
173 sg:pub.10.1007/bf00599623 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000545645
174 https://doi.org/10.1007/bf00599623
175 rdf:type schema:CreativeWork
176 sg:pub.10.1007/bf01799655 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052471770
177 https://doi.org/10.1007/bf01799655
178 rdf:type schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1078381873 schema:CreativeWork
180 https://app.dimensions.ai/details/publication/pub.1079298692 schema:CreativeWork
181 https://app.dimensions.ai/details/publication/pub.1079924872 schema:CreativeWork
182 https://app.dimensions.ai/details/publication/pub.1082148610 schema:CreativeWork
183 https://app.dimensions.ai/details/publication/pub.1082362258 schema:CreativeWork
184 https://doi.org/10.1002/mrm.1910200107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033082639
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1007/bf01799655 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052471770
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/0003-9861(79)90405-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052613509
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/0006-291x(82)91364-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051355578
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1042/bj1341067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010039604
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1042/bj1410761 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041874000
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1055/s-2007-1024648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057495499
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1056/nejm198308183090702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036349513
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1080/00140138608968287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009428916
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1111/j.1748-1716.1992.tb09264.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025835816
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1152/jappl.1989.66.2.591 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079257869
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1152/jappl.1990.69.3.1165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078539870
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1152/jappl.1991.70.3.1031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078131414
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1152/jappl.1992.72.2.590 schema:sameAs https://app.dimensions.ai/details/publication/pub.1076980134
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1172/jci110682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029312954
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1172/jci112090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048027077
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1249/00005768-198708000-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011416947
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1249/00005768-199008000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039147413
219 rdf:type schema:CreativeWork
220 https://doi.org/10.2337/diab.28.9.852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070733550
221 rdf:type schema:CreativeWork
222 https://www.grid.ac/institutes/grid.413745.0 schema:alternateName Hôpital Arnaud De Villeneuve
223 schema:name Laboratoire de Physiologie des Interactions, Service d'Exploration de la Fonction Respiratoire, Hôpital Arnaud de Villeneuve, F-34295, Montpellier cedex 05, France
224 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...