Endogenous nature of spontaneous bursting in hippocampal pyramidal neurons View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-12

AUTHORS

John J. Hablitz, Daniel Johnston

ABSTRACT

The normal spontaneous bursting behavior of hippocampal pyramidal neurons was investigated. Bursting frequency was found to be membrane potential dependent, the frequency increasing with maintained depolarization and decreasing upon hyperpolarization. Short depolarizing-current pulses would trigger bursts which outlasted the stimulus, and bursting continued when synaptic transmission had been blocked. The spontaneous bursts of these neurons, in contrast to bursts induced by convulsive agents, appear to exhibit the classical behavior of endogenous bursts as observed in invertebrate neurons. The endogenous bursts in hippocampal neurons may result, also, from an interplay of intrinsic membrane currents. More... »

PAGES

325-334

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00716267

DOI

http://dx.doi.org/10.1007/bf00716267

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003395336

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6765736


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