Ontology type: schema:ScholarlyArticle
1985-12
AUTHORSLise Christensen, Maja Nielsen, Berit Hølund, Inge Clemmensen
ABSTRACTThe distribution pattern of fibronectin in metaplastic carcinomas, stromal sarcomas, malignant cystosarcoma phyllodes tumours and histiocytic type lymphomas of the human female breast has been studied using the indirect immunoperoxidase technique on formalin fixed paraffin embedded tissue.Fibronectin was demonstrated as intensely stained strands between tumour cells forming an irregular network in metaplastic carcinomas and lymphomas. Stromal sarcomas and the malignant stromal component of the phyllodes tumours exhibited, in contrast, a uniform staining throughout tumour cells and stroma which was weaker than in adjacent normal-looking connective tissue.We suggest that the intense staining reaction of metaplastic carcinomas is due to the scirrhous reaction generally associated with invasive human breast carcinomas. The advantage of using fibronectin as a diagnostic tool in the differentiation of carcinoma/lymphoma versus sarcoma is the fact that the antigen is a stromal marker and its staining intensity is not influenced by the morphology or degree of differentiation of non-mesenchymal tumours. More... »
PAGES465-476
http://scigraph.springernature.com/pub.10.1007/bf00709993
DOIhttp://dx.doi.org/10.1007/bf00709993
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1016436721
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/2996215
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Breast Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carcinoma",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Diagnosis, Differential",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fibronectins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunoenzyme Techniques",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Phyllodes Tumor",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sarcoma",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Departments of Pathological Anatomy, Glostrup Hospital and Frederiksberg Hospital, University of Copenhagen, Denmark",
"Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Christensen",
"givenName": "Lise",
"id": "sg:person.07424553602.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07424553602.99"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Departments of Pathological Anatomy, Glostrup Hospital and Frederiksberg Hospital, University of Copenhagen, Denmark",
"Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Nielsen",
"givenName": "Maja",
"id": "sg:person.01356067025.65",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356067025.65"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Departments of Pathological Anatomy, Glostrup Hospital and Frederiksberg Hospital, University of Copenhagen, Denmark",
"Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "H\u00f8lund",
"givenName": "Berit",
"id": "sg:person.01042047321.15",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042047321.15"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Departments of Pathological Anatomy, Glostrup Hospital and Frederiksberg Hospital, University of Copenhagen, Denmark",
"Departments of Pathological Anatomy and Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Clemmensen",
"givenName": "Inge",
"id": "sg:person.01222545745.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222545745.06"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/bf00489906",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012622547",
"https://doi.org/10.1007/bf00489906"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00710658",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006705790",
"https://doi.org/10.1007/bf00710658"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00047692",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049446715",
"https://doi.org/10.1007/bf00047692"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00517142",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020244230",
"https://doi.org/10.1007/bf00517142"
],
"type": "CreativeWork"
}
],
"datePublished": "1985-12",
"datePublishedReg": "1985-12-01",
"description": "The distribution pattern of fibronectin in metaplastic carcinomas, stromal sarcomas, malignant cystosarcoma phyllodes tumours and histiocytic type lymphomas of the human female breast has been studied using the indirect immunoperoxidase technique on formalin fixed paraffin embedded tissue.Fibronectin was demonstrated as intensely stained strands between tumour cells forming an irregular network in metaplastic carcinomas and lymphomas. Stromal sarcomas and the malignant stromal component of the phyllodes tumours exhibited, in contrast, a uniform staining throughout tumour cells and stroma which was weaker than in adjacent normal-looking connective tissue.We suggest that the intense staining reaction of metaplastic carcinomas is due to the scirrhous reaction generally associated with invasive human breast carcinomas. The advantage of using fibronectin as a diagnostic tool in the differentiation of carcinoma/lymphoma versus sarcoma is the fact that the antigen is a stromal marker and its staining intensity is not influenced by the morphology or degree of differentiation of non-mesenchymal tumours.",
"genre": "article",
"id": "sg:pub.10.1007/bf00709993",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1009231",
"issn": [
"0174-7398",
"0174-7398"
],
"name": "Virchows Archiv A Pathological Anatomy and Histopathology",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "4",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "407"
}
],
"keywords": [
"metaplastic carcinoma",
"stromal sarcoma",
"phyllodes tumor",
"human female breast",
"female breast",
"tumor cells",
"invasive human breast carcinomas",
"malignant stromal component",
"non-mesenchymal tumors",
"indirect immunoperoxidase technique",
"cystosarcoma phyllodes tumors",
"human breast carcinoma",
"scirrhous reaction",
"type lymphoma",
"breast carcinoma",
"degree of differentiation",
"stromal markers",
"immunoperoxidase technique",
"intense staining reaction",
"carcinoma",
"sarcoma",
"stromal components",
"lymphoma",
"tumors",
"connective tissue",
"diagnostic tool",
"uniform staining",
"breast",
"staining reaction",
"fibronectin",
"tissue",
"cells",
"differentiation",
"antigen",
"stroma",
"formalin",
"staining",
"markers",
"paraffin",
"distribution patterns",
"contrast",
"patterns",
"reaction",
"degree",
"tool",
"intensity",
"components",
"technique",
"morphology",
"fact",
"advantages",
"strands",
"network",
"irregular network"
],
"name": "Differentiation between metaplastic carcinomas and sarcomas of the human female breast by fibronectin",
"pagination": "465-476",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1016436721"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf00709993"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"2996215"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf00709993",
"https://app.dimensions.ai/details/publication/pub.1016436721"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-10T09:43",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_218.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/bf00709993"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00709993'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00709993'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00709993'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00709993'
This table displays all metadata directly associated to this object as RDF triples.
189 TRIPLES
22 PREDICATES
94 URIs
82 LITERALS
16 BLANK NODES