Ontology type: schema:ScholarlyArticle
1986-07
AUTHORSH. Nagura, T. Koshikawa, Y. Fukuda, J. Asai
ABSTRACTDuring studies of the antigenic and functional properties of hepatic sinusoidal lining cells in situ, we found that only the sinusoidal endothelial cells share antigens with a peripheral blood macrophage subset capable of presenting soluble antigens and triggering autologous mixed lymphocyte reactions. They were HLA-DR+, OKM1−, OKM5+. Vascular endothelial cells in the portal areas and central veins were HLA-DR+, OKM1− and OKM5−. The sinusoidal endothelial cells also expressed an antigen found on helper/inducer (OKT4 and Leu3 a) T lymphocytes. Thus, the present study suggests that endothelial cells in different anatomic compartments in the liver heterogenously express surface antigens associated with monocytes, macrophages and T lymphocytes and possess distinct immunological functions. More... »
PAGES407-416
http://scigraph.springernature.com/pub.10.1007/bf00705413
DOIhttp://dx.doi.org/10.1007/bf00705413
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/3090771
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