Metabolism of halohydroquinones inRhodococcus chlorophenolicus PCP-1 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-06

AUTHORS

J. S. Uotila, V. H. Kitunen, T. Coote, T. Saastamoinen, M. Salkinoja-Salonen, J. H. A. Apajalahti

ABSTRACT

The actinomycete Rhodococcus chlorophenolicus PCP-1 metabolizes pentachlorophenol into ultimate inorganic end products via tetrachloro-p-hydroquinone. This intermediate was further dehalogenated in the cytoplasm requiring reductant in the cell free system. Tetrafluoro-p-hydroquinone and tetrabromo-p-hydroquinone were also dehalogenated. Chlorophenol analogs, thiol blocking agents and molecular oxygen inhibited the activity. The dehalogenating reactions led to 1,2,4-trihydroxybenzene, which was further metabolized into maleic acid. More... »

PAGES

119-126

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00695342

DOI

http://dx.doi.org/10.1007/bf00695342

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022969782

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7772938


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