Etude Ultrastructurale des Lésions Cérébrales de la Sclérose Tubéreuse de Bourneville View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1973-12

AUTHORS

J. L. Ribadeau Dumas, J. Poirier, R. Escourolle

ABSTRACT

The electron microscopic study of a cortical biopsy from a child presenting a Tuberous Sclerosis shows the importance of the astrocytic gliosis, the existence of abnormal cells of which two types can be recognized, and the presence of giant cells. All these cells are remarkable by the abundance of the ergastoplasm, the development of the Golgi apparatus, and the presence of membrane bound dense bodies. These cells are undoubtedly of astrocytic origin and appear very similar to the cells observed in a tumour of the caudate nucleus of another child affected by the same disease.These morphological data lead to believe that the cerebral abnormalities of the Tuberous Sclerosis essentially concern the astrocytes. The main characteristic of this astrocytic lesion would be its blastomatous potentiality. More... »

PAGES

259-270

References to SciGraph publications

  • 1936-09. Tuberous sclerosis in PSYCHIATRIC QUARTERLY
  • 1972-09. Fine structure of atypical cells in tuberous sclerosis in ACTA NEUROPATHOLOGICA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00691754

    DOI

    http://dx.doi.org/10.1007/bf00691754

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1050717553

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/4750189


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