P53, cell cycle control and apoptosis: Implications for cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-03

AUTHORS

Michael B. Kastan, Christine E. Canman, Christopher J. Leonard

ABSTRACT

Cellular proliferation depends on the rates of both cell division and cell death. Tumors frequently have decreased cell death as a primary mode of increased cell proliferation. Genetic changes resulting in loss of programmed cell death (apoptosis) are likely to be critical components of tumorigenesis. Many of the gene products which appear to control apoptotic tendencies are regulators of cell cycle progression; thus, cell cycle control and cell death appear to be tightly linked processes. P53 protein is an example of a gene product which affects both cell cycle progression and apoptosis. The ability of p53 overexpression to induce apoptosis may be a major reason why tumor cells frequently disable p53 during the transformation process. Unfortunately, the same genetic changes which cause loss of apoptosis during tumor development, may also result in tumor cell resistance to anti-neoplastic therapies which kill tumor cells by apoptosis. Elucidation of the genetic and biochemical controls of these cellular responses may provide insights into ways to induce cell death and thus hopefully suggest new targets for improving therapeutic index in the treatment of malignancies. More... »

PAGES

3-15

References to SciGraph publications

  • 1992-03. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours in NATURE
  • 1992-09. Effects of an Rb mutation in the mouse in NATURE
  • 1993-12. p21 is a universal inhibitor of cyclin kinases in NATURE
  • 1993-02. Apoptosis (the 1992 Frank Rose Memorial Lecture) in BRITISH JOURNAL OF CANCER
  • 1994-09. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens in NATURE
  • 1979-03. T antigen is bound to a host protein in SY40-transformed cells in NATURE
  • 1993-04. p53 is required for radiation-induced apoptosis in mouse thymocytes in NATURE
  • 1987-09. Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression in BRITISH JOURNAL OF CANCER
  • 1993-04. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 in NATURE
  • 1989-12. Mutations in the p53 gene occur in diverse human tumour types in NATURE
  • 1991-07. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 in NATURE
  • 1968-06. Delayed Initiation of DNA Synthesis in Irradiated Human Diploid Cells in NATURE
  • 1992-07. Retinoblastoma protein switches the E2F site from positive to negative element in NATURE
  • 1984-12. Participation of p53 cellular tumour antigen in transformation of normal embryonic cells in NATURE
  • 1990-12. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li–Fraumeni syndrome in NATURE
  • 1992-07. Wild-type p53 activates transcription in vitro in NATURE
  • 1992-07. Amplification of a gene encoding a p53-associated protein in human sarcomas in NATURE
  • 1991-06. The p53 tumour suppressor gene in NATURE
  • 1993-05. Gain of function mutations in p53 in NATURE GENETICS
  • 1993-04. Thymocyte apoptosis induced by p53-dependent and independent pathways in NATURE
  • 1992-09. Requirement for a functional Rb-1 gene in murine development in NATURE
  • 1992-09. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00690207

    DOI

    http://dx.doi.org/10.1007/bf00690207

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1013278307

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7606818


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Apoptosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Cycle", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Cycle Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Survival", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Transformation, Neoplastic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA Damage", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "G1 Phase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Regulation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genes, p53", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mutation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tumor Suppressor Protein p53", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "The Johns Hopkins Oncology Center, Baltimore, Madison, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kastan", 
            "givenName": "Michael B.", 
            "id": "sg:person.01277715415.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277715415.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "The Johns Hopkins Oncology Center, Baltimore, Madison, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Canman", 
            "givenName": "Christine E.", 
            "id": "sg:person.01213077223.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213077223.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "The Johns Hopkins Oncology Center, Baltimore, Madison, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Leonard", 
            "givenName": "Christopher J.", 
            "id": "sg:person.01327567124.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327567124.13"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/362849a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000557273", 
              "https://doi.org/10.1038/362849a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(85)80070-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001046047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.9.3602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001514552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/278261a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001770301", 
              "https://doi.org/10.1038/278261a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(79)90293-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003247971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.7.4.546", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004309332"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/312646a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004629945", 
              "https://doi.org/10.1038/312646a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.13.7.4242", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006063841"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.8.11.1285", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006728154"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.7.8.1572", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007024026"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/352345a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007959161", 
              "https://doi.org/10.1038/352345a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/362857a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008690526", 
              "https://doi.org/10.1038/362857a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/358080a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008811763", 
              "https://doi.org/10.1038/358080a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.7.7a.1126", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009683263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.7.2684", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012480709"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/359295a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013123356", 
              "https://doi.org/10.1038/359295a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.7.4.535", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013372391"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(90)90113-s", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014490539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90593-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014799709"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90244-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014811237"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.89.16.7491", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015184889"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.6.2026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018482128"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/358083a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019580671", 
              "https://doi.org/10.1038/358083a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/366701a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020218634", 
              "https://doi.org/10.1038/366701a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/358259a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020237383", 
              "https://doi.org/10.1038/358259a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(94)90379-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020595973"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.240450108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020771147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.240450108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020771147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.1987.186", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021906241", 
              "https://doi.org/10.1038/bjc.1987.186"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.1987.186", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021906241", 
              "https://doi.org/10.1038/bjc.1987.186"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.13.1.301", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022312785"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.5.2420", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024273914"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(91)90361-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026298033"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/371072a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026622134", 
              "https://doi.org/10.1038/371072a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0016-5085(93)90017-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027056662"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/356215a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027559823", 
              "https://doi.org/10.1038/356215a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(91)90560-l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028955720"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(93)90508-n", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030931670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/362847a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032575717", 
              "https://doi.org/10.1038/362847a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/excr.1994.1063", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032649061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/2181064a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033556486", 
              "https://doi.org/10.1038/2181064a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/348747a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034283595", 
              "https://doi.org/10.1038/348747a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(93)90499-g", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034836400"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.8.6.666", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035976884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.90.8.3516", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036741856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/359328a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036861399", 
              "https://doi.org/10.1038/359328a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(93)90719-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037459188"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/359288a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037982331", 
              "https://doi.org/10.1038/359288a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.12.6.2866", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038446565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(93)90500-p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038576682"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90243-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039400395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/09553008514552591", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039516320"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(94)90534-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040104577"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/342705a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041126170", 
              "https://doi.org/10.1038/342705a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.90.24.11623", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041670639"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng0593-42", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042763763", 
              "https://doi.org/10.1038/ng0593-42"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(93)90509-o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043118200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.1993.40", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043219900", 
              "https://doi.org/10.1038/bjc.1993.40"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bjc.1993.40", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043219900", 
              "https://doi.org/10.1038/bjc.1993.40"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.12.5320", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045383596"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90644-r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045937824"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/20.22.5947", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046565739"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90421-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047527074"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.14.4.2361", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047629092"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.5.2.151", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049561499"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.14.3.1815", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049773993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(92)90123-t", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049919165"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.90.8.3221", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052253459"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/351453a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052393971", 
              "https://doi.org/10.1038/351453a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.9.3754", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052456868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.10.11.5772", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053488905"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1411535", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062480839"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1589764", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062493032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1905840", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062512950"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1978757", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062515832"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2047879", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062519699"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2144057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062524133"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2144363", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062524134"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2144364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062524135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2554494", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062543708"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2683079", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062550422"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.3291120", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062604910"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.7973727", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062650847"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.8023157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062652004"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.8108732", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062652819"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.8266092", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062653900"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2307/3574634", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070377650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1992.tb05183.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1075491014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1992.tb05270.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077078713"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077647141", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077881311", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1991.tb08018.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1078039711"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079159747", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079893701", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081678137", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/66.6.1192", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082102830"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082566623", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082659220", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082659570", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082680104", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082683288", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082720599", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082720608", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082720611", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082752373", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082757421", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1993.tb05941.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082762184"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082771074", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082774653", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082775988", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082785753", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082791863", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1993.tb05678.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082807455"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082824617", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082835276", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1995-03", 
        "datePublishedReg": "1995-03-01", 
        "description": "Cellular proliferation depends on the rates of both cell division and cell death. Tumors frequently have decreased cell death as a primary mode of increased cell proliferation. Genetic changes resulting in loss of programmed cell death (apoptosis) are likely to be critical components of tumorigenesis. Many of the gene products which appear to control apoptotic tendencies are regulators of cell cycle progression; thus, cell cycle control and cell death appear to be tightly linked processes. P53 protein is an example of a gene product which affects both cell cycle progression and apoptosis. The ability of p53 overexpression to induce apoptosis may be a major reason why tumor cells frequently disable p53 during the transformation process. Unfortunately, the same genetic changes which cause loss of apoptosis during tumor development, may also result in tumor cell resistance to anti-neoplastic therapies which kill tumor cells by apoptosis. Elucidation of the genetic and biochemical controls of these cellular responses may provide insights into ways to induce cell death and thus hopefully suggest new targets for improving therapeutic index in the treatment of malignancies.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/bf00690207", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2502848", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2471805", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2634888", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.7137416", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1096239", 
            "issn": [
              "0167-7659", 
              "1573-7233"
            ], 
            "name": "Cancer and Metastasis Reviews", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "14"
          }
        ], 
        "name": "P53, cell cycle control and apoptosis: Implications for cancer", 
        "pagination": "3-15", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf00690207"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "3f4196a6693ef22dad1a516d16586b1545b145aded7044333aca9edf35971c8b"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1013278307"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "8605731"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "7606818"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf00690207", 
          "https://app.dimensions.ai/details/publication/pub.1013278307"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-15T09:04", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91466_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007/BF00690207"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00690207'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00690207'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00690207'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00690207'


     

    This table displays all metadata directly associated to this object as RDF triples.

    479 TRIPLES      21 PREDICATES      154 URIs      34 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf00690207 schema:about N0b8ef111d3f24a16b1e3c60d53b6a083
    2 N1d122ec984de4e41ba32b6382eb8bdc0
    3 N3122bb5d9730466ab4c254db42d5cc15
    4 N331f7168f3be4768bc1b8f99555879c8
    5 N4b9ad2134e4345f09083a97ca65e12a4
    6 N9684be0d2c14472598f89a0e50d57a57
    7 N997b7be8456d4acd81f665414d57e86e
    8 Nb6092af8a39d4a599f32ecebec34d553
    9 Nb9ca27ac23c14ee69d3548b3a105dc7e
    10 Nbaf090ec96d34f91b08bc3aebd1e3ba0
    11 Nc7ba3c7282414540b02b776843619581
    12 Nc8fa1672f7504ae0bde626c561ed8be3
    13 Nfe6f1f625a4e44aebe61f9afe144b74f
    14 anzsrc-for:06
    15 anzsrc-for:0601
    16 schema:author N07344112e50b4a42966989b57f1e6d85
    17 schema:citation sg:pub.10.1038/2181064a0
    18 sg:pub.10.1038/278261a0
    19 sg:pub.10.1038/312646a0
    20 sg:pub.10.1038/342705a0
    21 sg:pub.10.1038/348747a0
    22 sg:pub.10.1038/351453a0
    23 sg:pub.10.1038/352345a0
    24 sg:pub.10.1038/356215a0
    25 sg:pub.10.1038/358080a0
    26 sg:pub.10.1038/358083a0
    27 sg:pub.10.1038/358259a0
    28 sg:pub.10.1038/359288a0
    29 sg:pub.10.1038/359295a0
    30 sg:pub.10.1038/359328a0
    31 sg:pub.10.1038/362847a0
    32 sg:pub.10.1038/362849a0
    33 sg:pub.10.1038/362857a0
    34 sg:pub.10.1038/366701a0
    35 sg:pub.10.1038/371072a0
    36 sg:pub.10.1038/bjc.1987.186
    37 sg:pub.10.1038/bjc.1993.40
    38 sg:pub.10.1038/ng0593-42
    39 https://app.dimensions.ai/details/publication/pub.1077647141
    40 https://app.dimensions.ai/details/publication/pub.1077881311
    41 https://app.dimensions.ai/details/publication/pub.1079159747
    42 https://app.dimensions.ai/details/publication/pub.1079893701
    43 https://app.dimensions.ai/details/publication/pub.1081678137
    44 https://app.dimensions.ai/details/publication/pub.1082566623
    45 https://app.dimensions.ai/details/publication/pub.1082659220
    46 https://app.dimensions.ai/details/publication/pub.1082659570
    47 https://app.dimensions.ai/details/publication/pub.1082680104
    48 https://app.dimensions.ai/details/publication/pub.1082683288
    49 https://app.dimensions.ai/details/publication/pub.1082720599
    50 https://app.dimensions.ai/details/publication/pub.1082720608
    51 https://app.dimensions.ai/details/publication/pub.1082720611
    52 https://app.dimensions.ai/details/publication/pub.1082752373
    53 https://app.dimensions.ai/details/publication/pub.1082757421
    54 https://app.dimensions.ai/details/publication/pub.1082771074
    55 https://app.dimensions.ai/details/publication/pub.1082774653
    56 https://app.dimensions.ai/details/publication/pub.1082775988
    57 https://app.dimensions.ai/details/publication/pub.1082785753
    58 https://app.dimensions.ai/details/publication/pub.1082791863
    59 https://app.dimensions.ai/details/publication/pub.1082824617
    60 https://app.dimensions.ai/details/publication/pub.1082835276
    61 https://doi.org/10.1002/j.1460-2075.1991.tb08018.x
    62 https://doi.org/10.1002/j.1460-2075.1992.tb05183.x
    63 https://doi.org/10.1002/j.1460-2075.1992.tb05270.x
    64 https://doi.org/10.1002/j.1460-2075.1993.tb05678.x
    65 https://doi.org/10.1002/j.1460-2075.1993.tb05941.x
    66 https://doi.org/10.1002/jcb.240450108
    67 https://doi.org/10.1006/excr.1994.1063
    68 https://doi.org/10.1016/0016-5085(93)90017-7
    69 https://doi.org/10.1016/0092-8674(79)90293-9
    70 https://doi.org/10.1016/0092-8674(90)90113-s
    71 https://doi.org/10.1016/0092-8674(91)90361-2
    72 https://doi.org/10.1016/0092-8674(91)90560-l
    73 https://doi.org/10.1016/0092-8674(92)90123-t
    74 https://doi.org/10.1016/0092-8674(92)90243-6
    75 https://doi.org/10.1016/0092-8674(92)90244-7
    76 https://doi.org/10.1016/0092-8674(92)90421-8
    77 https://doi.org/10.1016/0092-8674(92)90593-2
    78 https://doi.org/10.1016/0092-8674(92)90644-r
    79 https://doi.org/10.1016/0092-8674(93)90499-g
    80 https://doi.org/10.1016/0092-8674(93)90500-p
    81 https://doi.org/10.1016/0092-8674(93)90508-n
    82 https://doi.org/10.1016/0092-8674(93)90509-o
    83 https://doi.org/10.1016/0092-8674(93)90719-7
    84 https://doi.org/10.1016/0092-8674(94)90379-4
    85 https://doi.org/10.1016/0092-8674(94)90534-7
    86 https://doi.org/10.1016/s0092-8674(85)80070-2
    87 https://doi.org/10.1073/pnas.76.5.2420
    88 https://doi.org/10.1073/pnas.89.16.7491
    89 https://doi.org/10.1073/pnas.90.24.11623
    90 https://doi.org/10.1073/pnas.90.8.3221
    91 https://doi.org/10.1073/pnas.90.8.3516
    92 https://doi.org/10.1073/pnas.91.12.5320
    93 https://doi.org/10.1073/pnas.91.6.2026
    94 https://doi.org/10.1073/pnas.91.7.2684
    95 https://doi.org/10.1073/pnas.91.9.3602
    96 https://doi.org/10.1073/pnas.91.9.3754
    97 https://doi.org/10.1080/09553008514552591
    98 https://doi.org/10.1093/jnci/66.6.1192
    99 https://doi.org/10.1093/nar/20.22.5947
    100 https://doi.org/10.1101/gad.5.2.151
    101 https://doi.org/10.1101/gad.7.4.535
    102 https://doi.org/10.1101/gad.7.4.546
    103 https://doi.org/10.1101/gad.7.7a.1126
    104 https://doi.org/10.1101/gad.7.8.1572
    105 https://doi.org/10.1101/gad.8.11.1285
    106 https://doi.org/10.1101/gad.8.6.666
    107 https://doi.org/10.1126/science.1411535
    108 https://doi.org/10.1126/science.1589764
    109 https://doi.org/10.1126/science.1905840
    110 https://doi.org/10.1126/science.1978757
    111 https://doi.org/10.1126/science.2047879
    112 https://doi.org/10.1126/science.2144057
    113 https://doi.org/10.1126/science.2144363
    114 https://doi.org/10.1126/science.2144364
    115 https://doi.org/10.1126/science.2554494
    116 https://doi.org/10.1126/science.2683079
    117 https://doi.org/10.1126/science.3291120
    118 https://doi.org/10.1126/science.7973727
    119 https://doi.org/10.1126/science.8023157
    120 https://doi.org/10.1126/science.8108732
    121 https://doi.org/10.1126/science.8266092
    122 https://doi.org/10.1128/mcb.10.11.5772
    123 https://doi.org/10.1128/mcb.12.6.2866
    124 https://doi.org/10.1128/mcb.13.1.301
    125 https://doi.org/10.1128/mcb.13.7.4242
    126 https://doi.org/10.1128/mcb.14.3.1815
    127 https://doi.org/10.1128/mcb.14.4.2361
    128 https://doi.org/10.2307/3574634
    129 schema:datePublished 1995-03
    130 schema:datePublishedReg 1995-03-01
    131 schema:description Cellular proliferation depends on the rates of both cell division and cell death. Tumors frequently have decreased cell death as a primary mode of increased cell proliferation. Genetic changes resulting in loss of programmed cell death (apoptosis) are likely to be critical components of tumorigenesis. Many of the gene products which appear to control apoptotic tendencies are regulators of cell cycle progression; thus, cell cycle control and cell death appear to be tightly linked processes. P53 protein is an example of a gene product which affects both cell cycle progression and apoptosis. The ability of p53 overexpression to induce apoptosis may be a major reason why tumor cells frequently disable p53 during the transformation process. Unfortunately, the same genetic changes which cause loss of apoptosis during tumor development, may also result in tumor cell resistance to anti-neoplastic therapies which kill tumor cells by apoptosis. Elucidation of the genetic and biochemical controls of these cellular responses may provide insights into ways to induce cell death and thus hopefully suggest new targets for improving therapeutic index in the treatment of malignancies.
    132 schema:genre research_article
    133 schema:inLanguage en
    134 schema:isAccessibleForFree false
    135 schema:isPartOf Nb5211a82ae2f45aa9e8047b3341007e8
    136 Nfee8f692a1174184bc24f765e67002cf
    137 sg:journal.1096239
    138 schema:name P53, cell cycle control and apoptosis: Implications for cancer
    139 schema:pagination 3-15
    140 schema:productId N0bdaccbc81df437bb291d1b00daf4e29
    141 N82f8814a297f40a4a199e16b3a326fc1
    142 N92d5ffceef8d40eaaf3d7928bd5a9319
    143 Na92872970b3e4c9eb47c0fd007029c01
    144 Nf8b57c19b3904b899bdc4ec35d2eade8
    145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013278307
    146 https://doi.org/10.1007/bf00690207
    147 schema:sdDatePublished 2019-04-15T09:04
    148 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    149 schema:sdPublisher Ne372e100a5eb4606aa1b489b773a4e0a
    150 schema:url http://link.springer.com/10.1007/BF00690207
    151 sgo:license sg:explorer/license/
    152 sgo:sdDataset articles
    153 rdf:type schema:ScholarlyArticle
    154 N07344112e50b4a42966989b57f1e6d85 rdf:first sg:person.01277715415.41
    155 rdf:rest Ne8bccbb12df7402a9c654cdecbf21513
    156 N0b8ef111d3f24a16b1e3c60d53b6a083 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Mutation
    158 rdf:type schema:DefinedTerm
    159 N0bdaccbc81df437bb291d1b00daf4e29 schema:name doi
    160 schema:value 10.1007/bf00690207
    161 rdf:type schema:PropertyValue
    162 N1d122ec984de4e41ba32b6382eb8bdc0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    163 schema:name Humans
    164 rdf:type schema:DefinedTerm
    165 N3122bb5d9730466ab4c254db42d5cc15 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    166 schema:name Cell Transformation, Neoplastic
    167 rdf:type schema:DefinedTerm
    168 N331f7168f3be4768bc1b8f99555879c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    169 schema:name Neoplasms
    170 rdf:type schema:DefinedTerm
    171 N4b9ad2134e4345f09083a97ca65e12a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    172 schema:name Tumor Suppressor Protein p53
    173 rdf:type schema:DefinedTerm
    174 N82f8814a297f40a4a199e16b3a326fc1 schema:name pubmed_id
    175 schema:value 7606818
    176 rdf:type schema:PropertyValue
    177 N92d5ffceef8d40eaaf3d7928bd5a9319 schema:name nlm_unique_id
    178 schema:value 8605731
    179 rdf:type schema:PropertyValue
    180 N9684be0d2c14472598f89a0e50d57a57 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Gene Expression Regulation
    182 rdf:type schema:DefinedTerm
    183 N997b7be8456d4acd81f665414d57e86e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    184 schema:name Cell Survival
    185 rdf:type schema:DefinedTerm
    186 Na92872970b3e4c9eb47c0fd007029c01 schema:name readcube_id
    187 schema:value 3f4196a6693ef22dad1a516d16586b1545b145aded7044333aca9edf35971c8b
    188 rdf:type schema:PropertyValue
    189 Nb5211a82ae2f45aa9e8047b3341007e8 schema:volumeNumber 14
    190 rdf:type schema:PublicationVolume
    191 Nb6092af8a39d4a599f32ecebec34d553 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    192 schema:name Cell Cycle
    193 rdf:type schema:DefinedTerm
    194 Nb9ca27ac23c14ee69d3548b3a105dc7e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Cell Cycle Proteins
    196 rdf:type schema:DefinedTerm
    197 Nbaf090ec96d34f91b08bc3aebd1e3ba0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    198 schema:name Apoptosis
    199 rdf:type schema:DefinedTerm
    200 Nc7ba3c7282414540b02b776843619581 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name Genes, p53
    202 rdf:type schema:DefinedTerm
    203 Nc8fa1672f7504ae0bde626c561ed8be3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name DNA Damage
    205 rdf:type schema:DefinedTerm
    206 Nd376a365b0ea48cf9001fdc00a3d4b35 rdf:first sg:person.01327567124.13
    207 rdf:rest rdf:nil
    208 Ne372e100a5eb4606aa1b489b773a4e0a schema:name Springer Nature - SN SciGraph project
    209 rdf:type schema:Organization
    210 Ne8bccbb12df7402a9c654cdecbf21513 rdf:first sg:person.01213077223.41
    211 rdf:rest Nd376a365b0ea48cf9001fdc00a3d4b35
    212 Nf8b57c19b3904b899bdc4ec35d2eade8 schema:name dimensions_id
    213 schema:value pub.1013278307
    214 rdf:type schema:PropertyValue
    215 Nfe6f1f625a4e44aebe61f9afe144b74f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    216 schema:name G1 Phase
    217 rdf:type schema:DefinedTerm
    218 Nfee8f692a1174184bc24f765e67002cf schema:issueNumber 1
    219 rdf:type schema:PublicationIssue
    220 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    221 schema:name Biological Sciences
    222 rdf:type schema:DefinedTerm
    223 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    224 schema:name Biochemistry and Cell Biology
    225 rdf:type schema:DefinedTerm
    226 sg:grant.2471805 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00690207
    227 rdf:type schema:MonetaryGrant
    228 sg:grant.2502848 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00690207
    229 rdf:type schema:MonetaryGrant
    230 sg:grant.2634888 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00690207
    231 rdf:type schema:MonetaryGrant
    232 sg:grant.7137416 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00690207
    233 rdf:type schema:MonetaryGrant
    234 sg:journal.1096239 schema:issn 0167-7659
    235 1573-7233
    236 schema:name Cancer and Metastasis Reviews
    237 rdf:type schema:Periodical
    238 sg:person.01213077223.41 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    239 schema:familyName Canman
    240 schema:givenName Christine E.
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213077223.41
    242 rdf:type schema:Person
    243 sg:person.01277715415.41 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    244 schema:familyName Kastan
    245 schema:givenName Michael B.
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277715415.41
    247 rdf:type schema:Person
    248 sg:person.01327567124.13 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    249 schema:familyName Leonard
    250 schema:givenName Christopher J.
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327567124.13
    252 rdf:type schema:Person
    253 sg:pub.10.1038/2181064a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033556486
    254 https://doi.org/10.1038/2181064a0
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1038/278261a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001770301
    257 https://doi.org/10.1038/278261a0
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1038/312646a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004629945
    260 https://doi.org/10.1038/312646a0
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/342705a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041126170
    263 https://doi.org/10.1038/342705a0
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1038/348747a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034283595
    266 https://doi.org/10.1038/348747a0
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/351453a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052393971
    269 https://doi.org/10.1038/351453a0
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/352345a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007959161
    272 https://doi.org/10.1038/352345a0
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/356215a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027559823
    275 https://doi.org/10.1038/356215a0
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/358080a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008811763
    278 https://doi.org/10.1038/358080a0
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1038/358083a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019580671
    281 https://doi.org/10.1038/358083a0
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1038/358259a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020237383
    284 https://doi.org/10.1038/358259a0
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1038/359288a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037982331
    287 https://doi.org/10.1038/359288a0
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1038/359295a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013123356
    290 https://doi.org/10.1038/359295a0
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1038/359328a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036861399
    293 https://doi.org/10.1038/359328a0
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1038/362847a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032575717
    296 https://doi.org/10.1038/362847a0
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1038/362849a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000557273
    299 https://doi.org/10.1038/362849a0
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1038/362857a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008690526
    302 https://doi.org/10.1038/362857a0
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/366701a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020218634
    305 https://doi.org/10.1038/366701a0
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/371072a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026622134
    308 https://doi.org/10.1038/371072a0
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/bjc.1987.186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021906241
    311 https://doi.org/10.1038/bjc.1987.186
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/bjc.1993.40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043219900
    314 https://doi.org/10.1038/bjc.1993.40
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/ng0593-42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042763763
    317 https://doi.org/10.1038/ng0593-42
    318 rdf:type schema:CreativeWork
    319 https://app.dimensions.ai/details/publication/pub.1077647141 schema:CreativeWork
    320 https://app.dimensions.ai/details/publication/pub.1077881311 schema:CreativeWork
    321 https://app.dimensions.ai/details/publication/pub.1079159747 schema:CreativeWork
    322 https://app.dimensions.ai/details/publication/pub.1079893701 schema:CreativeWork
    323 https://app.dimensions.ai/details/publication/pub.1081678137 schema:CreativeWork
    324 https://app.dimensions.ai/details/publication/pub.1082566623 schema:CreativeWork
    325 https://app.dimensions.ai/details/publication/pub.1082659220 schema:CreativeWork
    326 https://app.dimensions.ai/details/publication/pub.1082659570 schema:CreativeWork
    327 https://app.dimensions.ai/details/publication/pub.1082680104 schema:CreativeWork
    328 https://app.dimensions.ai/details/publication/pub.1082683288 schema:CreativeWork
    329 https://app.dimensions.ai/details/publication/pub.1082720599 schema:CreativeWork
    330 https://app.dimensions.ai/details/publication/pub.1082720608 schema:CreativeWork
    331 https://app.dimensions.ai/details/publication/pub.1082720611 schema:CreativeWork
    332 https://app.dimensions.ai/details/publication/pub.1082752373 schema:CreativeWork
    333 https://app.dimensions.ai/details/publication/pub.1082757421 schema:CreativeWork
    334 https://app.dimensions.ai/details/publication/pub.1082771074 schema:CreativeWork
    335 https://app.dimensions.ai/details/publication/pub.1082774653 schema:CreativeWork
    336 https://app.dimensions.ai/details/publication/pub.1082775988 schema:CreativeWork
    337 https://app.dimensions.ai/details/publication/pub.1082785753 schema:CreativeWork
    338 https://app.dimensions.ai/details/publication/pub.1082791863 schema:CreativeWork
    339 https://app.dimensions.ai/details/publication/pub.1082824617 schema:CreativeWork
    340 https://app.dimensions.ai/details/publication/pub.1082835276 schema:CreativeWork
    341 https://doi.org/10.1002/j.1460-2075.1991.tb08018.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1078039711
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1002/j.1460-2075.1992.tb05183.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1075491014
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1002/j.1460-2075.1992.tb05270.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1077078713
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1002/j.1460-2075.1993.tb05678.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082807455
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1002/j.1460-2075.1993.tb05941.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1082762184
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1002/jcb.240450108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020771147
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1006/excr.1994.1063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032649061
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1016/0016-5085(93)90017-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027056662
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1016/0092-8674(79)90293-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003247971
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1016/0092-8674(90)90113-s schema:sameAs https://app.dimensions.ai/details/publication/pub.1014490539
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1016/0092-8674(91)90361-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026298033
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1016/0092-8674(91)90560-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1028955720
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1016/0092-8674(92)90123-t schema:sameAs https://app.dimensions.ai/details/publication/pub.1049919165
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1016/0092-8674(92)90243-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039400395
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1016/0092-8674(92)90244-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014811237
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1016/0092-8674(92)90421-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047527074
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1016/0092-8674(92)90593-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014799709
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1016/0092-8674(92)90644-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1045937824
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1016/0092-8674(93)90499-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1034836400
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1016/0092-8674(93)90500-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1038576682
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1016/0092-8674(93)90508-n schema:sameAs https://app.dimensions.ai/details/publication/pub.1030931670
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1016/0092-8674(93)90509-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1043118200
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1016/0092-8674(93)90719-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037459188
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1016/0092-8674(94)90379-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020595973
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1016/0092-8674(94)90534-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040104577
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1016/s0092-8674(85)80070-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001046047
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1073/pnas.76.5.2420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024273914
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1073/pnas.89.16.7491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015184889
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1073/pnas.90.24.11623 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041670639
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1073/pnas.90.8.3221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052253459
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1073/pnas.90.8.3516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036741856
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1073/pnas.91.12.5320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045383596
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1073/pnas.91.6.2026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018482128
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1073/pnas.91.7.2684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012480709
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1073/pnas.91.9.3602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001514552
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1073/pnas.91.9.3754 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052456868
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1080/09553008514552591 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039516320
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1093/jnci/66.6.1192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082102830
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1093/nar/20.22.5947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046565739
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1101/gad.5.2.151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049561499
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1101/gad.7.4.535 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013372391
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1101/gad.7.4.546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004309332
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1101/gad.7.7a.1126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009683263
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1101/gad.7.8.1572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007024026
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1101/gad.8.11.1285 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006728154
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1101/gad.8.6.666 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035976884
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1126/science.1411535 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062480839
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1126/science.1589764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062493032
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1126/science.1905840 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062512950
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1126/science.1978757 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062515832
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1126/science.2047879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062519699
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1126/science.2144057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062524133
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1126/science.2144363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062524134
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1126/science.2144364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062524135
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1126/science.2554494 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062543708
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1126/science.2683079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062550422
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1126/science.3291120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062604910
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1126/science.7973727 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062650847
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1126/science.8023157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652004
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1126/science.8108732 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652819
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1126/science.8266092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062653900
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1128/mcb.10.11.5772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053488905
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1128/mcb.12.6.2866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038446565
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1128/mcb.13.1.301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022312785
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1128/mcb.13.7.4242 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006063841
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.1128/mcb.14.3.1815 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049773993
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1128/mcb.14.4.2361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047629092
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.2307/3574634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070377650
    476 rdf:type schema:CreativeWork
    477 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
    478 schema:name The Johns Hopkins Oncology Center, Baltimore, Madison, USA
    479 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...