Protection from ifosfamide-induced alopecia by topical thiols in young rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-07

AUTHORS

Jurij Stekar, Peter Hilgard, Wilfried Holtei, Uwe Riemer

ABSTRACT

An animal model for testing substances that might prevent alopecia induced by oxazaphosphorines has been developed. It is based on the fact that the rat pups experience virtually total hair loss following administration of oxazaphosphorines. Using this model, we showed that epicutaneous treatment with sodium thioglycollate prevented ifosfamide-induced hair loss on the treated area. These experiments indicate that prevention of oxazaphosphorine-induced alopecia in man may be achieved by topical thiols. More... »

PAGES

306-307

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00684892

DOI

http://dx.doi.org/10.1007/bf00684892

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003245849

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2295118


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