Modes of DAPI banding and simultaneous in situ hybridization View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1993-05

AUTHORS

Henry H. Q. Heng, Lap-Chee Tsui

ABSTRACT

By controlling the degree of chromatin denaturation through formamide incubation, or by heat treatment and/or by high pH, three types of high quality 4',6-diamidino-2-phenylindole (DAPI) bands can be produced sequentially on the same set of 5-bromo-2'-deoxyuridine (BrdU)-incorporated chromosomes: first DAPI multibanding (the equivalent of Q-banding), then partial C-banding including distamycin A (DA)/DAPI banding, and finally C-banding pattern. It is assumed that the different DAPI-chromatin interactions following these treatments reflect the different chromatin structures at the chromosomal sites. Since the DAPI banding protocol is compatible with in situ hybridization, the combination of fluorescent in situ hybridization (FISH) with DAPI banding allows the simultaneous detection of signals from the DNA probes and the identification of the chromosomal band location of the probe. We demonstrate this useful application with the localization of the cystic fibrosis and Duchenne muscular dystrophy gene probes to their appropriate bands. More... »

PAGES

325-332

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00661275

DOI

http://dx.doi.org/10.1007/bf00661275

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045339873

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8325164


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Banding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cystic Fibrosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorescent Dyes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Formamides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hot Temperature", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrogen-Ion Concentration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Situ Hybridization, Fluorescence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscular Dystrophies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nucleic Acid Denaturation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hospital for Sick Children", 
          "id": "https://www.grid.ac/institutes/grid.42327.30", 
          "name": [
            "Department of Molecular and Medical Genetics, University of Toronto, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada", 
            "Department of Genetics, Hospital for Sick Children, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heng", 
        "givenName": "Henry H. Q.", 
        "id": "sg:person.01264600044.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264600044.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital for Sick Children", 
          "id": "https://www.grid.ac/institutes/grid.42327.30", 
          "name": [
            "Department of Molecular and Medical Genetics, University of Toronto, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada", 
            "Department of Genetics, Hospital for Sick Children, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsui", 
        "givenName": "Lap-Chee", 
        "id": "sg:person.01243057047.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243057047.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.87.19.7757", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006031318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/6.11.3519", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006439783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(88)90159-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007864148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4827(78)90177-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011385999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00194638", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011644077", 
          "https://doi.org/10.1007/bf00194638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000132547", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012183963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00333988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015897948", 
          "https://doi.org/10.1007/bf00333988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.16.6223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016569093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000132684", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019013534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0027-5107(88)90246-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024715752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/16.9.3951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025317570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.5.1695", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026233740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0888-7543(92)90412-l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026828048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4827(76)90450-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027962472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00292840", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031861142", 
          "https://doi.org/10.1007/bf00292840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/1050-3862(91)90005-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033890655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/1050-3862(91)90005-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033890655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.88.17.7557", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045690887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00197258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045995476", 
          "https://doi.org/10.1007/bf00197258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.20.9509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048809875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00330407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049948932", 
          "https://doi.org/10.1007/bf00330407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1251198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062469856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2294592", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062530794"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2772657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062558148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078924719", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1993-05", 
    "datePublishedReg": "1993-05-01", 
    "description": "By controlling the degree of chromatin denaturation through formamide incubation, or by heat treatment and/or by high pH, three types of high quality 4',6-diamidino-2-phenylindole (DAPI) bands can be produced sequentially on the same set of 5-bromo-2'-deoxyuridine (BrdU)-incorporated chromosomes: first DAPI multibanding (the equivalent of Q-banding), then partial C-banding including distamycin A (DA)/DAPI banding, and finally C-banding pattern. It is assumed that the different DAPI-chromatin interactions following these treatments reflect the different chromatin structures at the chromosomal sites. Since the DAPI banding protocol is compatible with in situ hybridization, the combination of fluorescent in situ hybridization (FISH) with DAPI banding allows the simultaneous detection of signals from the DNA probes and the identification of the chromosomal band location of the probe. We demonstrate this useful application with the localization of the cystic fibrosis and Duchenne muscular dystrophy gene probes to their appropriate bands.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00661275", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1312277", 
        "issn": [
          "0009-5915", 
          "1432-0886"
        ], 
        "name": "Chromosoma", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "102"
      }
    ], 
    "name": "Modes of DAPI banding and simultaneous in situ hybridization", 
    "pagination": "325-332", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d7f90487605feb46a5ca482bbe747e2b30c2ee06162284a646fb08cb99010093"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8325164"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "2985138R"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00661275"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1045339873"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00661275", 
      "https://app.dimensions.ai/details/publication/pub.1045339873"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:18", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000372_0000000372/records_117100_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00661275"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00661275'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00661275'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00661275'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00661275'


 

This table displays all metadata directly associated to this object as RDF triples.

205 TRIPLES      21 PREDICATES      66 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00661275 schema:about N058df6de19724d59b54a7d3b9a25f383
2 N1376ba289f374508b74f845b867a5c31
3 N13d05e8025a44da88b8cdaa15a72624a
4 N2819f4526b474e5ab2e648a478c4d7d0
5 N290d744be14349b0a6450c1b0a487cdc
6 N345eba710f6b4295acb662948e497cd0
7 N394fe3394a394343b9900f57f3ad8b27
8 N641d79d214b3495bbe95a3a007682ec3
9 N691d7d78dc924a5fb9f20ee32cc4884d
10 N887baabf20cd4b6199a1b29e4ccd7afd
11 Naedb12f5f35843fc9f94220989b99b9d
12 Nb0e33e0b9bf044928668e508489bace4
13 Nb259b0c30c964596bccd64d84d62ce5c
14 anzsrc-for:06
15 anzsrc-for:0604
16 schema:author Nf86ffec9b2c241e88eecc7c264d22a65
17 schema:citation sg:pub.10.1007/bf00194638
18 sg:pub.10.1007/bf00197258
19 sg:pub.10.1007/bf00292840
20 sg:pub.10.1007/bf00330407
21 sg:pub.10.1007/bf00333988
22 https://app.dimensions.ai/details/publication/pub.1078924719
23 https://doi.org/10.1016/0014-4827(76)90450-x
24 https://doi.org/10.1016/0014-4827(78)90177-5
25 https://doi.org/10.1016/0027-5107(88)90246-1
26 https://doi.org/10.1016/0092-8674(88)90159-6
27 https://doi.org/10.1016/0888-7543(92)90412-l
28 https://doi.org/10.1016/1050-3862(91)90005-c
29 https://doi.org/10.1073/pnas.87.16.6223
30 https://doi.org/10.1073/pnas.87.19.7757
31 https://doi.org/10.1073/pnas.88.17.7557
32 https://doi.org/10.1073/pnas.89.20.9509
33 https://doi.org/10.1073/pnas.89.5.1695
34 https://doi.org/10.1093/nar/16.9.3951
35 https://doi.org/10.1093/nar/6.11.3519
36 https://doi.org/10.1126/science.1251198
37 https://doi.org/10.1126/science.2294592
38 https://doi.org/10.1126/science.2772657
39 https://doi.org/10.1159/000132547
40 https://doi.org/10.1159/000132684
41 schema:datePublished 1993-05
42 schema:datePublishedReg 1993-05-01
43 schema:description By controlling the degree of chromatin denaturation through formamide incubation, or by heat treatment and/or by high pH, three types of high quality 4',6-diamidino-2-phenylindole (DAPI) bands can be produced sequentially on the same set of 5-bromo-2'-deoxyuridine (BrdU)-incorporated chromosomes: first DAPI multibanding (the equivalent of Q-banding), then partial C-banding including distamycin A (DA)/DAPI banding, and finally C-banding pattern. It is assumed that the different DAPI-chromatin interactions following these treatments reflect the different chromatin structures at the chromosomal sites. Since the DAPI banding protocol is compatible with in situ hybridization, the combination of fluorescent in situ hybridization (FISH) with DAPI banding allows the simultaneous detection of signals from the DNA probes and the identification of the chromosomal band location of the probe. We demonstrate this useful application with the localization of the cystic fibrosis and Duchenne muscular dystrophy gene probes to their appropriate bands.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf N55e72dd1f86a4befaa597257e9a11165
48 N83c81260740e4b0892cb71ce4e0b96e0
49 sg:journal.1312277
50 schema:name Modes of DAPI banding and simultaneous in situ hybridization
51 schema:pagination 325-332
52 schema:productId N050756804f7d44009b30ca6b01547daf
53 N34cdf04e49724ec18128f5b9badceb84
54 N7fbf0b73732a4eecad29fde4ed45bed9
55 Nacff9fc968ab460890766771e6c284dc
56 Nc0dec86b35684d7c8c814b8d242d3cfb
57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045339873
58 https://doi.org/10.1007/bf00661275
59 schema:sdDatePublished 2019-04-11T14:18
60 schema:sdLicense https://scigraph.springernature.com/explorer/license/
61 schema:sdPublisher N6e4508bb1d6a4ac58129ce681cb9cd19
62 schema:url http://link.springer.com/10.1007/BF00661275
63 sgo:license sg:explorer/license/
64 sgo:sdDataset articles
65 rdf:type schema:ScholarlyArticle
66 N050756804f7d44009b30ca6b01547daf schema:name doi
67 schema:value 10.1007/bf00661275
68 rdf:type schema:PropertyValue
69 N058df6de19724d59b54a7d3b9a25f383 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Chromosome Banding
71 rdf:type schema:DefinedTerm
72 N1376ba289f374508b74f845b867a5c31 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Cells, Cultured
74 rdf:type schema:DefinedTerm
75 N13d05e8025a44da88b8cdaa15a72624a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Cystic Fibrosis
77 rdf:type schema:DefinedTerm
78 N2819f4526b474e5ab2e648a478c4d7d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Muscular Dystrophies
80 rdf:type schema:DefinedTerm
81 N290d744be14349b0a6450c1b0a487cdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name In Situ Hybridization, Fluorescence
83 rdf:type schema:DefinedTerm
84 N345eba710f6b4295acb662948e497cd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Formamides
86 rdf:type schema:DefinedTerm
87 N34cdf04e49724ec18128f5b9badceb84 schema:name nlm_unique_id
88 schema:value 2985138R
89 rdf:type schema:PropertyValue
90 N394fe3394a394343b9900f57f3ad8b27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Humans
92 rdf:type schema:DefinedTerm
93 N55e72dd1f86a4befaa597257e9a11165 schema:issueNumber 5
94 rdf:type schema:PublicationIssue
95 N641d79d214b3495bbe95a3a007682ec3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Fluorescent Dyes
97 rdf:type schema:DefinedTerm
98 N691d7d78dc924a5fb9f20ee32cc4884d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Hot Temperature
100 rdf:type schema:DefinedTerm
101 N6e4508bb1d6a4ac58129ce681cb9cd19 schema:name Springer Nature - SN SciGraph project
102 rdf:type schema:Organization
103 N74cb263ca4dd49eb881590a87ddd3b9f rdf:first sg:person.01243057047.05
104 rdf:rest rdf:nil
105 N7fbf0b73732a4eecad29fde4ed45bed9 schema:name pubmed_id
106 schema:value 8325164
107 rdf:type schema:PropertyValue
108 N83c81260740e4b0892cb71ce4e0b96e0 schema:volumeNumber 102
109 rdf:type schema:PublicationVolume
110 N887baabf20cd4b6199a1b29e4ccd7afd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Indoles
112 rdf:type schema:DefinedTerm
113 Nacff9fc968ab460890766771e6c284dc schema:name readcube_id
114 schema:value d7f90487605feb46a5ca482bbe747e2b30c2ee06162284a646fb08cb99010093
115 rdf:type schema:PropertyValue
116 Naedb12f5f35843fc9f94220989b99b9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Nucleic Acid Denaturation
118 rdf:type schema:DefinedTerm
119 Nb0e33e0b9bf044928668e508489bace4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Lymphocytes
121 rdf:type schema:DefinedTerm
122 Nb259b0c30c964596bccd64d84d62ce5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Hydrogen-Ion Concentration
124 rdf:type schema:DefinedTerm
125 Nc0dec86b35684d7c8c814b8d242d3cfb schema:name dimensions_id
126 schema:value pub.1045339873
127 rdf:type schema:PropertyValue
128 Nf86ffec9b2c241e88eecc7c264d22a65 rdf:first sg:person.01264600044.49
129 rdf:rest N74cb263ca4dd49eb881590a87ddd3b9f
130 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
131 schema:name Biological Sciences
132 rdf:type schema:DefinedTerm
133 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
134 schema:name Genetics
135 rdf:type schema:DefinedTerm
136 sg:journal.1312277 schema:issn 0009-5915
137 1432-0886
138 schema:name Chromosoma
139 rdf:type schema:Periodical
140 sg:person.01243057047.05 schema:affiliation https://www.grid.ac/institutes/grid.42327.30
141 schema:familyName Tsui
142 schema:givenName Lap-Chee
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243057047.05
144 rdf:type schema:Person
145 sg:person.01264600044.49 schema:affiliation https://www.grid.ac/institutes/grid.42327.30
146 schema:familyName Heng
147 schema:givenName Henry H. Q.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264600044.49
149 rdf:type schema:Person
150 sg:pub.10.1007/bf00194638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011644077
151 https://doi.org/10.1007/bf00194638
152 rdf:type schema:CreativeWork
153 sg:pub.10.1007/bf00197258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045995476
154 https://doi.org/10.1007/bf00197258
155 rdf:type schema:CreativeWork
156 sg:pub.10.1007/bf00292840 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031861142
157 https://doi.org/10.1007/bf00292840
158 rdf:type schema:CreativeWork
159 sg:pub.10.1007/bf00330407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049948932
160 https://doi.org/10.1007/bf00330407
161 rdf:type schema:CreativeWork
162 sg:pub.10.1007/bf00333988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015897948
163 https://doi.org/10.1007/bf00333988
164 rdf:type schema:CreativeWork
165 https://app.dimensions.ai/details/publication/pub.1078924719 schema:CreativeWork
166 https://doi.org/10.1016/0014-4827(76)90450-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027962472
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/0014-4827(78)90177-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011385999
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/0027-5107(88)90246-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024715752
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/0092-8674(88)90159-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007864148
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/0888-7543(92)90412-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1026828048
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/1050-3862(91)90005-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1033890655
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1073/pnas.87.16.6223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016569093
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1073/pnas.87.19.7757 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006031318
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1073/pnas.88.17.7557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045690887
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1073/pnas.89.20.9509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048809875
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1073/pnas.89.5.1695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026233740
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1093/nar/16.9.3951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025317570
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1093/nar/6.11.3519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006439783
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1126/science.1251198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062469856
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1126/science.2294592 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062530794
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1126/science.2772657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062558148
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1159/000132547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012183963
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1159/000132684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019013534
201 rdf:type schema:CreativeWork
202 https://www.grid.ac/institutes/grid.42327.30 schema:alternateName Hospital for Sick Children
203 schema:name Department of Genetics, Hospital for Sick Children, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada
204 Department of Molecular and Medical Genetics, University of Toronto, 555 University Avenue, M5G 1H8, Toronto, Ontario, Canada
205 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...