Transient hypoxia: Ventilatory response after vagotomy and during artificial phasic inflation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1979-02

AUTHORS

S. Delpierre, C. Guillot, M. Fornaris, Y. Jammes, C. Grimaud

ABSTRACT

The early ventilatory response to transient hypoxia was examined in the anaesthetized rabbit. In intact spontaneously breathing animals, an increase in tidal volume (VT) with an accompanying slight increase in inspiratory duration (TI) and a decrease in the expiratory duration (TE) was observed. After vagotomy, the ventilatory response was distinguished by a greater increase in VT and a significant decrease in TI and TE. In another group of artificially ventilated rabbits, an increase in inspiratory volume with a simultaneous decrease in breathing frequency was found to involve a smaller reflex increase in phrenic inspiratory discharge after onset of transient hypoxia. These observations suggest that afferents from pulmonary vagal stretch receptors inhibit those from arterial chemoreceptors. More... »

PAGES

53-57

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00622905

DOI

http://dx.doi.org/10.1007/bf00622905

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030952022

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34825


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