A controlled trial of intermittent oral acetylcysteine in the long-term treatment of chronic bronchitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-09

AUTHORS

C. Grassi, G. C. Morandini

ABSTRACT

In 69 out-patients with chronic bronchitis in 6 centres the effects of acetylcysteine 600 mg daily, 3 days a week for 6 months, and a placebo have been compared in a double-blind controlled trial. Thirty-five patients were treated with the mucolytic and 34 with the dummy preparation. In the former the clinical course of the chronic bronchitis improved to a greater extent and a significantly lower number of exacerbations was observed. The advantages of long-term oral treatment with the mucolytic in chronic bronchitis suggest that it may be useful as an alternative to long-term antibiotic prophylaxis, or to complement brief courses of antibiotics, in addition to the usual physiotherapy. More... »

PAGES

393-396

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00606554

DOI

http://dx.doi.org/10.1007/bf00606554

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040116365

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/786665


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