Ontology type: schema:ScholarlyArticle
1971-12
AUTHORS ABSTRACTThe technique of the double sucrose gap was used to perform voltage clamp experiments on small segments of isolated auricular trabeculae of the frog heart. The voltage dependence and kinetics of the delayed rectification current were analyzed. The total outward current could be dissociated into two components: one component is defined as leakage current (Il) and shows inward rectification; a second component is the delayed rectification current (IK). The activation ofIKcan be described by a Hodgkin and Huxley type of kinetical model. The rate constants are found to be smaller by a factor of about 103 than those described in the giant axon of the squid.The results are used to compute the activation of the delayed rectification current and the total outward current during a normal action potential. More... »
PAGES321-331
http://scigraph.springernature.com/pub.10.1007/bf00588003
DOIhttp://dx.doi.org/10.1007/bf00588003
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/5316323
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