Kinetics of Na inactivation in frog atria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1971-06

AUTHORS

H. G. Haas, R. Kern, H. M. Einwächter, M. Tarr

ABSTRACT

In frog atria, time and voltage dependence of inactivation and reactivation of fast transient Na current were studied using the sucrose-gap voltage clamp technique. Experiments were done at 4–7° C.Fast inward current inactivated by conditioning depolarizing clamps. The relation between steady-state inactivation and membrane potential is represented by an S-shaped curve similar to that observed in squid axon. At the resting level the availability of the Na-carrying system is about 60–70%.During depolarizing clamps inactivation of Na current follows an approximately exponential time course with time constants between 1.5 and 8 msec.Recovery from inactivation (reactivation) is much slower than development of inactivation. Time constants between 100 and 600 msec were observed during the recovery process following a repolarization or a hyperpolarization.A ratio between the time constants of inactivation and reactivation in the order of 1∶50 was found when the two processes were studied at the same potential level.In the frog atrial action potential the slow reactivation of the Na system is reflected by a relative refractory period reaching far beyond full repolarization.Assuming that the slow course of Na reactivation is an inherent feature of Na kinetics, the inactivation variable (h) of the Hodgkin-Huxley theory (1952d) seems inadequate to describe the inactivation-reactivation process in frog atria. Formally fast inactivation and slow reactivation could be accounted for by replacing the variableh with two variables which both decrease on depolarization but largely differ in the rate constants. More... »

PAGES

141-157

References to SciGraph publications

  • 1970-06. Voltage and time dependence of excitatory sodium current in cooled sheep Purkinje fibres in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1969-01. Two components of inward current in myocardial muscle fibers in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1968-06. Voltage clamp experiments on frog atrial heart muscle fibres with the sucrose gap technique in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1970-12. Electrical activity and metabolism in cardiac tissue: An experimental and theoretical study in THE JOURNAL OF MEMBRANE BIOLOGY
  • 1966-09. Excitatory membrane current in heart muscle (Purkinje fibers) in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1965-09. Nachweis von zwei Komponenten in der Anstiegsphase des Aktionspotentials von Froschmyokardfasern in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1969-06. Existence and role of a slow inward current during the frog atrial action potential in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00586445

    DOI

    http://dx.doi.org/10.1007/bf00586445

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1031535848

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/5101235


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1116", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical Physiology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Action Potentials", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA", 
              "id": "http://www.grid.ac/institutes/grid.412016.0", 
              "name": [
                "I. Physiologisches Institut der Universit\u00e4t, Akademiestr. 3, BRD-6900, Heidelberg, Germany", 
                "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Haas", 
            "givenName": "H. G.", 
            "id": "sg:person.0113537423.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0113537423.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA", 
              "id": "http://www.grid.ac/institutes/grid.412016.0", 
              "name": [
                "I. Physiologisches Institut der Universit\u00e4t, Akademiestr. 3, BRD-6900, Heidelberg, Germany", 
                "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kern", 
            "givenName": "R.", 
            "id": "sg:person.051570563.62", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.051570563.62"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA", 
              "id": "http://www.grid.ac/institutes/grid.412016.0", 
              "name": [
                "I. Physiologisches Institut der Universit\u00e4t, Akademiestr. 3, BRD-6900, Heidelberg, Germany", 
                "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Einw\u00e4chter", 
            "givenName": "H. M.", 
            "id": "sg:person.010374753724.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010374753724.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA", 
              "id": "http://www.grid.ac/institutes/grid.412016.0", 
              "name": [
                "I. Physiologisches Institut der Universit\u00e4t, Akademiestr. 3, BRD-6900, Heidelberg, Germany", 
                "Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tarr", 
            "givenName": "M.", 
            "id": "sg:person.01031353706.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031353706.47"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf00412938", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046873590", 
              "https://doi.org/10.1007/bf00412938"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00586657", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039250880", 
              "https://doi.org/10.1007/bf00586657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00362729", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009268455", 
              "https://doi.org/10.1007/bf00362729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00587018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011512209", 
              "https://doi.org/10.1007/bf00587018"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00592084", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051667322", 
              "https://doi.org/10.1007/bf00592084"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00362740", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032527445", 
              "https://doi.org/10.1007/bf00362740"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01868015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010604945", 
              "https://doi.org/10.1007/bf01868015"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1971-06", 
        "datePublishedReg": "1971-06-01", 
        "description": "In frog atria, time and voltage dependence of inactivation and reactivation of fast transient Na current were studied using the sucrose-gap voltage clamp technique. Experiments were done at 4\u20137\u00b0 C.Fast inward current inactivated by conditioning depolarizing clamps. The relation between steady-state inactivation and membrane potential is represented by an S-shaped curve similar to that observed in squid axon. At the resting level the availability of the Na-carrying system is about 60\u201370%.During depolarizing clamps inactivation of Na current follows an approximately exponential time course with time constants between 1.5 and 8 msec.Recovery from inactivation (reactivation) is much slower than development of inactivation. Time constants between 100 and 600 msec were observed during the recovery process following a repolarization or a hyperpolarization.A ratio between the time constants of inactivation and reactivation in the order of 1\u223650 was found when the two processes were studied at the same potential level.In the frog atrial action potential the slow reactivation of the Na system is reflected by a relative refractory period reaching far beyond full repolarization.Assuming that the slow course of Na reactivation is an inherent feature of Na kinetics, the inactivation variable (h) of the Hodgkin-Huxley theory (1952d) seems inadequate to describe the inactivation-reactivation process in frog atria. Formally fast inactivation and slow reactivation could be accounted for by replacing the variableh with two variables which both decrease on depolarization but largely differ in the rate constants.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/bf00586445", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1005222", 
            "issn": [
              "0031-6768", 
              "1432-2013"
            ], 
            "name": "Pfl\u00fcgers Archiv - European Journal of Physiology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "323"
          }
        ], 
        "keywords": [
          "frog atrium", 
          "sucrose gap voltage clamp technique", 
          "atrial action potential", 
          "steady-state inactivation", 
          "relative refractory period", 
          "voltage-clamp technique", 
          "transient Na", 
          "slow course", 
          "clamp technique", 
          "action potentials", 
          "refractory period", 
          "full repolarization", 
          "development of inactivation", 
          "atrium", 
          "Na current", 
          "exponential time course", 
          "time course", 
          "repolarization", 
          "slow reactivation", 
          "reactivation", 
          "membrane potential", 
          "fast inactivation", 
          "inactivation variable", 
          "msec", 
          "Na kinetics", 
          "Na inactivation", 
          "NA system", 
          "inactivation", 
          "voltage dependence", 
          "course", 
          "hyperpolarization", 
          "levels", 
          "depolarization", 
          "clamp", 
          "potential level", 
          "time constants", 
          "Hodgkin-Huxley theory", 
          "period", 
          "recovery", 
          "recovery process", 
          "variables", 
          "conditioning", 
          "potential", 
          "Na", 
          "development", 
          "ratio", 
          "time", 
          "curves", 
          "features", 
          "availability", 
          "system", 
          "relation", 
          "technique", 
          "kinetics", 
          "process", 
          "current", 
          "order", 
          "experiments", 
          "inherent features", 
          "squid", 
          "rate constants", 
          "dependence", 
          "constants", 
          "theory"
        ], 
        "name": "Kinetics of Na inactivation in frog atria", 
        "pagination": "141-157", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1031535848"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf00586445"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "5101235"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf00586445", 
          "https://app.dimensions.ai/details/publication/pub.1031535848"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T15:45", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_138.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/bf00586445"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00586445'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00586445'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00586445'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00586445'


     

    This table displays all metadata directly associated to this object as RDF triples.

    183 TRIPLES      21 PREDICATES      99 URIs      84 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf00586445 schema:about Ncde5df85a6cd427992a2c1f73731dd23
    2 Neb365ec5f85c4dc79b898746fa531879
    3 anzsrc-for:11
    4 anzsrc-for:1116
    5 schema:author Ndd513cf7baba4b41a83ceeb97fe73bc6
    6 schema:citation sg:pub.10.1007/bf00362729
    7 sg:pub.10.1007/bf00362740
    8 sg:pub.10.1007/bf00412938
    9 sg:pub.10.1007/bf00586657
    10 sg:pub.10.1007/bf00587018
    11 sg:pub.10.1007/bf00592084
    12 sg:pub.10.1007/bf01868015
    13 schema:datePublished 1971-06
    14 schema:datePublishedReg 1971-06-01
    15 schema:description In frog atria, time and voltage dependence of inactivation and reactivation of fast transient Na current were studied using the sucrose-gap voltage clamp technique. Experiments were done at 4–7° C.Fast inward current inactivated by conditioning depolarizing clamps. The relation between steady-state inactivation and membrane potential is represented by an S-shaped curve similar to that observed in squid axon. At the resting level the availability of the Na-carrying system is about 60–70%.During depolarizing clamps inactivation of Na current follows an approximately exponential time course with time constants between 1.5 and 8 msec.Recovery from inactivation (reactivation) is much slower than development of inactivation. Time constants between 100 and 600 msec were observed during the recovery process following a repolarization or a hyperpolarization.A ratio between the time constants of inactivation and reactivation in the order of 1∶50 was found when the two processes were studied at the same potential level.In the frog atrial action potential the slow reactivation of the Na system is reflected by a relative refractory period reaching far beyond full repolarization.Assuming that the slow course of Na reactivation is an inherent feature of Na kinetics, the inactivation variable (h) of the Hodgkin-Huxley theory (1952d) seems inadequate to describe the inactivation-reactivation process in frog atria. Formally fast inactivation and slow reactivation could be accounted for by replacing the variableh with two variables which both decrease on depolarization but largely differ in the rate constants.
    16 schema:genre article
    17 schema:isAccessibleForFree false
    18 schema:isPartOf N791aace40a0b4c07be8761247ff6e5c3
    19 Nefbcfed4d5ce4431889883ae753d8d50
    20 sg:journal.1005222
    21 schema:keywords Hodgkin-Huxley theory
    22 NA system
    23 Na
    24 Na current
    25 Na inactivation
    26 Na kinetics
    27 action potentials
    28 atrial action potential
    29 atrium
    30 availability
    31 clamp
    32 clamp technique
    33 conditioning
    34 constants
    35 course
    36 current
    37 curves
    38 dependence
    39 depolarization
    40 development
    41 development of inactivation
    42 experiments
    43 exponential time course
    44 fast inactivation
    45 features
    46 frog atrium
    47 full repolarization
    48 hyperpolarization
    49 inactivation
    50 inactivation variable
    51 inherent features
    52 kinetics
    53 levels
    54 membrane potential
    55 msec
    56 order
    57 period
    58 potential
    59 potential level
    60 process
    61 rate constants
    62 ratio
    63 reactivation
    64 recovery
    65 recovery process
    66 refractory period
    67 relation
    68 relative refractory period
    69 repolarization
    70 slow course
    71 slow reactivation
    72 squid
    73 steady-state inactivation
    74 sucrose gap voltage clamp technique
    75 system
    76 technique
    77 theory
    78 time
    79 time constants
    80 time course
    81 transient Na
    82 variables
    83 voltage dependence
    84 voltage-clamp technique
    85 schema:name Kinetics of Na inactivation in frog atria
    86 schema:pagination 141-157
    87 schema:productId N15accac31b0c4305a89ba86d182aeb87
    88 N92081ff464f54ff2ba1e4d4c02628f78
    89 Nf387edd528194473b08d1fa888a82c57
    90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031535848
    91 https://doi.org/10.1007/bf00586445
    92 schema:sdDatePublished 2022-09-02T15:45
    93 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    94 schema:sdPublisher Na470b5cb8cfa44efae927b0f1f87bee4
    95 schema:url https://doi.org/10.1007/bf00586445
    96 sgo:license sg:explorer/license/
    97 sgo:sdDataset articles
    98 rdf:type schema:ScholarlyArticle
    99 N15accac31b0c4305a89ba86d182aeb87 schema:name dimensions_id
    100 schema:value pub.1031535848
    101 rdf:type schema:PropertyValue
    102 N5270473561e143efaf98f90c374c87d6 rdf:first sg:person.010374753724.53
    103 rdf:rest N8f489e48005f4b999e3186cddaad130f
    104 N791aace40a0b4c07be8761247ff6e5c3 schema:issueNumber 2
    105 rdf:type schema:PublicationIssue
    106 N8f489e48005f4b999e3186cddaad130f rdf:first sg:person.01031353706.47
    107 rdf:rest rdf:nil
    108 N92081ff464f54ff2ba1e4d4c02628f78 schema:name doi
    109 schema:value 10.1007/bf00586445
    110 rdf:type schema:PropertyValue
    111 Na470b5cb8cfa44efae927b0f1f87bee4 schema:name Springer Nature - SN SciGraph project
    112 rdf:type schema:Organization
    113 Ncde5df85a6cd427992a2c1f73731dd23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    114 schema:name Action Potentials
    115 rdf:type schema:DefinedTerm
    116 Ndd513cf7baba4b41a83ceeb97fe73bc6 rdf:first sg:person.0113537423.28
    117 rdf:rest Neec42892afe346d69b2a56558a55156a
    118 Neb365ec5f85c4dc79b898746fa531879 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    119 schema:name Animals
    120 rdf:type schema:DefinedTerm
    121 Neec42892afe346d69b2a56558a55156a rdf:first sg:person.051570563.62
    122 rdf:rest N5270473561e143efaf98f90c374c87d6
    123 Nefbcfed4d5ce4431889883ae753d8d50 schema:volumeNumber 323
    124 rdf:type schema:PublicationVolume
    125 Nf387edd528194473b08d1fa888a82c57 schema:name pubmed_id
    126 schema:value 5101235
    127 rdf:type schema:PropertyValue
    128 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    129 schema:name Medical and Health Sciences
    130 rdf:type schema:DefinedTerm
    131 anzsrc-for:1116 schema:inDefinedTermSet anzsrc-for:
    132 schema:name Medical Physiology
    133 rdf:type schema:DefinedTerm
    134 sg:journal.1005222 schema:issn 0031-6768
    135 1432-2013
    136 schema:name Pflügers Archiv - European Journal of Physiology
    137 schema:publisher Springer Nature
    138 rdf:type schema:Periodical
    139 sg:person.01031353706.47 schema:affiliation grid-institutes:grid.412016.0
    140 schema:familyName Tarr
    141 schema:givenName M.
    142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031353706.47
    143 rdf:type schema:Person
    144 sg:person.010374753724.53 schema:affiliation grid-institutes:grid.412016.0
    145 schema:familyName Einwächter
    146 schema:givenName H. M.
    147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010374753724.53
    148 rdf:type schema:Person
    149 sg:person.0113537423.28 schema:affiliation grid-institutes:grid.412016.0
    150 schema:familyName Haas
    151 schema:givenName H. G.
    152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0113537423.28
    153 rdf:type schema:Person
    154 sg:person.051570563.62 schema:affiliation grid-institutes:grid.412016.0
    155 schema:familyName Kern
    156 schema:givenName R.
    157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.051570563.62
    158 rdf:type schema:Person
    159 sg:pub.10.1007/bf00362729 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009268455
    160 https://doi.org/10.1007/bf00362729
    161 rdf:type schema:CreativeWork
    162 sg:pub.10.1007/bf00362740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032527445
    163 https://doi.org/10.1007/bf00362740
    164 rdf:type schema:CreativeWork
    165 sg:pub.10.1007/bf00412938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046873590
    166 https://doi.org/10.1007/bf00412938
    167 rdf:type schema:CreativeWork
    168 sg:pub.10.1007/bf00586657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039250880
    169 https://doi.org/10.1007/bf00586657
    170 rdf:type schema:CreativeWork
    171 sg:pub.10.1007/bf00587018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011512209
    172 https://doi.org/10.1007/bf00587018
    173 rdf:type schema:CreativeWork
    174 sg:pub.10.1007/bf00592084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051667322
    175 https://doi.org/10.1007/bf00592084
    176 rdf:type schema:CreativeWork
    177 sg:pub.10.1007/bf01868015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010604945
    178 https://doi.org/10.1007/bf01868015
    179 rdf:type schema:CreativeWork
    180 grid-institutes:grid.412016.0 schema:alternateName Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA
    181 schema:name Department of Physiology, University of Kansas Medical Center, Rainbow Boulevard, 66103, Kansas City, Kansas, USA
    182 I. Physiologisches Institut der Universität, Akademiestr. 3, BRD-6900, Heidelberg, Germany
    183 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...