Measurements of the criticalPO2 of renal mitochondria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1971-09

AUTHORS

W. Stolp, V. Thiemann, D. Weber, Ch. Weiss

ABSTRACT

The criticalPO2 of isolated mitochondria from the cortex and outer medullary region of the rat kidney was polarographically measured using the O2-platinum-electrode. With succinate for substrate at 37°C and 25°C mean criticalPO2-values of 1.54 Torr (SD±0.58) and 1.01 Torr (SD±0.46) were found resp. Using malate for substrate the corresponding mean values were 0.92 Torr (SD±0.28 and 0.65 Torr (SD±0.25). A positive linear relationship between O2-uptake and criticalPO2 was observed. The results are compared with data on the O2-consumption of rat and dog renal cortex in situ and withPO2-values measured in the same organs. On the basis of the results here presented with regard to the lowestPO2-values found in the renal cortex of the dog an additional explanation of the flow limitation of the renal O2-consumption is developed. More... »

PAGES

250-257

References to SciGraph publications

  • 1955-06. A Simple and Rapid Assay of Oxidative Phosphorylation in NATURE
  • 1960-01. Beziehungen des O2-Verbrauchs der Niere zu Durchblutung und Glomerulusfiltrat bei Änderung des arteriellen Druckes in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1960-05. Hämodynamik des Nierenmarks in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1969-12. The oxygen supply of the rat kidney: Measurements of intrarenalpO2 in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1961-11. Die Abhängigkeit des O2-Verbrauchs der Niere von der Na-Rückresorption in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00586387

    DOI

    http://dx.doi.org/10.1007/bf00586387

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1006712663

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/5101957


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