Hypotensive and peripheral vascular effects in healthy volunteers of repeated oral administration of pinacidil View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-09

AUTHORS

J. L. Saumet, F. Dubois, P. Girard, A. Geloen, J. P. Boissel

ABSTRACT

The hypotensive and peripheral vascular effects of two different oral formulations of pinacidil were investigated in twelve healthy male volunteers.Arterial blood pressure, heart rate and calf blood flow were measured on Days 1 and 7. The vasodilator activity of both formulations was confirmed by a significant increase in calf blood flow on both days, which was correlated with a significant decrease in diastolic blood pressure.There was no differences between the tablet and the pellet. More... »

PAGES

527-529

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00558137

DOI

http://dx.doi.org/10.1007/bf00558137

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006121695

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2598994


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